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Related lectures (32)

Delves into the fundamentals of medicinal chemistry, emphasizing the interrogation of Structure-Activity Relationships (SAR) in drug design.

Interrogating SAR: Medicinal Chemistry

Covers medicinal chemistry basics, high-throughput screening, lead discovery milestones, and compound selectivity in drug optimization.

Fragment-Based Drug Discovery: Concepts & Technologies

Covers the concepts and technologies of fragment-based drug discovery, exploring hit identification, lead optimization, and screening methods.

Pharmacodynamics: Ligand-Receptor Binding and Drug Effects

Explores ligand-receptor binding, drug effects, efficacy, potency, and biased agonism in pharmacodynamics.

Chemical Biology: High-Throughput and High-Content Screening

Covers Chemical Biology, high-throughput screening, RNA interference, CRISPR-Cas9, and organoid differentiation for drug discovery.

Drug Discovery: Computational Approaches

Explores the EXSCALATE4COV project, focusing on computational drug discovery for COVID-19 treatments and the collaboration between academia and industry.

Fragment-Based Drug Discovery: Concepts & Technologies

Covers the concepts and technologies of fragment-based drug discovery, hit identification methods, and its application in target-based drug discovery.

The ClpXP Proteolytic Complex: Basic Principles to Drug Discovery

Explores the ClpXP proteolytic complex, its drug targeting potential, and antimicrobial applications through compound screening.

Pharmacodynamics: Ligand-Receptor Interactions and Drug Effects

Explores ligand-receptor interactions, drug effects, modulation mechanisms, and factors influencing drug responses.

Pharmacodynamics: Ligand Concentration, Binding, and Effect

Explores the relationship between ligand concentration, binding, and effect, focusing on allosteric modulators and types of pharmacological antagonists.

DNA-Encoded Libraries

Explores DNA-encoded libraries for drug discovery, covering synthesis techniques, pros and cons, and diverse DEL methods.

Synthetic Biology: Therapeutic Advancement

Introduces synthetic biology for disease treatment, covering RNA therapeutics, drug discovery, and gene circuits.

Deep Generative Models in Drug Discovery

Explores the application of deep generative models in drug discovery, focusing on designing small molecules and optimizing molecular structures.

Kidney-on-a-Chip Technologies

Covers the state-of-the-art kidney-on-chip technologies aiming to facilitate pharmaceutical research and eliminate animal testing.

Pharmacodynamics exercises

Covers the analysis of binding measurements and toxin kinetics in pharmacodynamics.

Protein Engineering & In vitro Evolution

Explores protein engineering, screening methods, scaffold properties, computational design, and continuous evolution of biomolecules.

Identifying Drug Targets: Safety and Efficacy

Delves into identifying drug targets, ensuring efficacy, and maintaining safety in medical chemistry, covering genetic tests, chirality, stereochemistry, drug resistance, and drug-likeness rules.

Predicting COVID-19 Therapeutic Mechanisms

Explores computational methods to predict COVID-19 therapeutic mechanisms through drug repurposing and machine learning.

Total Synthesis: Regidins and Ecteinascidin-743

Explores the total synthesis of Regidins and Ecteinascidin-743, along with the unique structure of (+)-Peganumine A.

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