Explores protein aggregation in neurodegenerative diseases, emphasizing the need to rethink treatment strategies and understand the role of post-translational modifications.
Explores Tau pathologies in Alzheimer's and related disorders, covering hyperphosphorylation, propagation, genetic associations, and therapeutic interventions.
Explores Alzheimer's disease, anxiety, pain, and the renin-angiotensin system, including the development of the first renin inhibitor for clinical treatment.
Covers Parkinson's disease, its symptoms, diagnosis challenges, and current treatment options, emphasizing the need for early biomarkers and disease-modifying therapies.
Delves into protein aggregation mechanisms using C. elegans, covering misfolding, aggregation pathways, kinetics, chaperones, and stochastic nucleation.
Explores the principles and programming of Deep Brain Stimulation for neurological disorders, focusing on therapeutic window adjustments and pulse width alterations.
Explores the evolution, principles, and applications of Deep Brain Stimulation, focusing on its history, mechanisms, electrode configurations, and future prospects.