Publications related to Epilepsy

Ambulatory seizure detection

Purpose of review: To review recent advances in the field of seizure detection in ambulatory patients with epilepsy. Recent findings: Recent studies have shown that wrist or arm wearable sensors, using 3D-accelerometry, electrodermal activity or photopleth ...

2024

Resource-Efficient Continual Learning for Personalized Online Seizure Detection

David Atienza Alonso, Giovanni Ansaloni, José Angel Miranda Calero, Jonathan Dan, Amirhossein Shahbazinia, Flavio Ponzina

Epilepsy, a major neurological disease, requires careful diagnosis and treatment. However, the detection of epileptic seizures remains a significant challenge. Current clinical practice relies on expert analysis of EEG signals, a process that is time-consu ...

IEEE2024

Integrated Wireless Power, Data Communication, and Thermal Sensing System for Autonomous Multisite Brain Implants

Implanted medical devices (IMDs) have been widely developed to support the monitoring and recording of biological data inside the body or brain. Wirelessly powered IMDs, a subset of implantable electronics, have been proposed to eliminate the limitations r ...

EPFL2024

Hardware Implementation of Digital Signal Processing Algorithms for Programmable Epilepsy Control Systems

Keyvan Farhang Razi

Epilepsy is a common chronic neurological disorder that causes recurring seizures and affects more than 50 million people worldwide. Implantable medical devices (IMDs) are regarded as effective tools to cure patients who suffer from refractory epilepsy. Se ...

EPFL2023

Combined use of intraoperative MRI and awake tailored microsurgical resection to respect functional neural networks: preliminary experience

Constantin Tuleasca

INTRODUCTION: The combined use of intraoperative MRI and awake surgery is a tailored microsurgical resection to respect functional neural networks (mainly the language and motor ones). Intraoperative MRI has been classically considered to increase the exte ...

2023

Hyperdimensional computing for biosignal monitoring: Applications for epilepsy detection

Una Pale

Hyperdimensional (HD) computing is a novel approach to machine learning inspired by neuroscience, which uses vectors in a hyper-dimensional space to represent data and models. This approach has gained significant interest in recent years with applications ...

EPFL2023

Enhancing Epileptic Seizure Detection with EEG Feature Embeddings

Mahsa Shoaran, Bingzhao Zhu, Arman Zarei

Epilepsy is one of the most prevalent brain disorders that disrupts the lives of millions worldwide. For patients with drug-resistant seizures, there exist implantable devices capable of monitoring neural activity, promptly triggering neurostimulation to r ...

ArXiv2023

How I became myself after merging with a computer: Does human-machine symbiosis raise human rights issues?

Marcello Ienca

Novel usages of brain stimulation combined with artificially intelligent (AI) systems promise to address a large range of diseases. These new conjoined technologies, such as brain-computer interfaces (BCI), are increasingly used in experimental and clinica ...

ELSEVIER SCIENCE INC2023

Miniaturised, Wireless and Distributed Neural Interface Toward Cortical Visual Prosthesis

Gian Luca Barbruni

Over the last decades, implantable neural interfaces have been extensively explored and effectively deployed to address neurological and mental health disorders. The existing solutions present several limitations. Firstly, the physical size of the implanta ...

EPFL2023

Recent Developments on the Use of Nanomaterials for the Treatment of Epilepsy

Sandrine Gerber, Sara María Garcia Pedrero

Epilepsy affects more than 40 million people worldwide, constituting one of the most debilitating disorders of the Central Nervous System (CNS). It results from an imbalance in the electrical activity of neurons, which is primarily mediated by calcium ions ...

2022

Disruption of layer-specific visual processing in a model of focal neocortical epilepsy

Silvestro Micera, Matteo Vissani

The epileptic brain is the result of a sequence of events transforming normal neuronal populations into hyperexcitable networks supporting recurrent seizure generation. These modifications are known to induce fundamental alterations of circuit function and ...

OXFORD UNIV PRESS INC2022

Approximate Zero-Crossing: A new interpretable, highly discriminative and low-complexity feature for EEG and iEEG seizure detection

David Atienza Alonso, Tomas Teijeiro Campo, Una Pale, Renato Zanetti

Objective: Long-term monitoring of people with epilepsy based on electroencephalography (EEG) and intracranial EEG (iEEG) has the potential to deliver key clinical information for personalised epilepsy treatment. More specifically, in outpatient settings, ...

2022

Personalized seizure signature: An interpretable approach to false alarm reduction for long‐term epileptic seizure detection

David Atienza Alonso, Amir Aminifar, Tomas Teijeiro Campo, Dionisije Sopic

Objective Long-term automatic detection of focal seizures remains one of the major challenges in epilepsy due to the unacceptably high number of false alarms from state-of-the-art methods. Our aim was to investigate to what extent a new patient-specific ap ...

2022

INCLASS: Incremental Classification Strategy for Self-Aware Epileptic Seizure Detection

David Atienza Alonso, Giovanni Ansaloni, Tomas Teijeiro Campo, Renaud Marquis

Wearable Health Companions allow the unobtrusive monitoring of patients affected by chronic conditions. In particular, by acquiring and interpreting bio-signals, they enable the detection of acute episodes in cardiac and neurological ailments. Nevertheless ...

IEEE2022

Exploration of Hyperdimensional Computing Strategies for Enhanced Learning on Epileptic Seizure Detection

David Atienza Alonso, Tomas Teijeiro Campo, Una Pale

Wearable and unobtrusive monitoring and prediction of epileptic seizures has the potential to significantly increase the life quality of patients, but is still an unreached goal due to challenges of real-time detection and wearable devices design. Hyperdim ...

2022

M2D2: Maximum-Mean-Discrepancy Decoder for Temporal Localization of Epileptic Brain Activities

David Atienza Alonso, Amir Aminifar, Alireza Amirshahi, Anthony Hitchcock Thomas

Recent years have seen growing interest in leveraging deep learning models for monitoring epilepsy patients based on electroencephalographic (EEG) signals. However, these approaches often exhibit poor generalization when applied outside of the setting in w ...

2022

Multi-Centroid Hyperdimensional Computing Approach for Epileptic Seizure Detection

David Atienza Alonso, Tomas Teijeiro Campo, Una Pale

Long-term monitoring of patients with epilepsy presents a challenging problem from the engineering perspective of real-time detection and wearable devices design. It requires new solutions that allow continuous unobstructed monitoring and reliable detectio ...

2022

Epileptic Seizure Detection With Patient-Specific Feature and Channel Selection for Low-power Applications

Alexandre Schmid, Keyvan Farhang Razi

An accurate epileptic seizure detector using intracranial electroencephalography (iEEG) recordings, suitable for low-power wearable/implantable applications, is presented. Eleven time-domain features with low hardware complexity are employed in the feature ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2022

Hardware-Friendly Random Forest Classification of iEEG Signals for Implantable Seizure Detection

Alexandre Schmid, Keyvan Farhang Razi

Early and accurate detection of epileptic seizures is an extremely important therapeutic goal due to the severity of complications it can prevent. To this end, a low-power machine learning-based seizure detection implemented on an FPGA is proposed in this ...

IEEE2022

Low-Intensity Electrostimulation Enhances Neuroregeneration and Improves Erectile Function in a Rat Model of Cavernous Nerve Injury

Nikolaos Stergiopoulos, Mikaël Nils Sturny, Rodrigo Araujo Fraga Da Silva

Background: Neurogenic erectile dysfunction (ED) following radical prostatectomy (RP) is a frequent complication often leading to erectile tissue remodeling and permanent ED. Low-intensity electrostimulation (LIES) has been shown to enhance peripheral nerv ...

ELSEVIER SCI LTD2022