Publications related to Microelectrode

Bodily implant microelectrode and bodily implant microelectrode fabrication method

Sandro Carrara, Diego Ghezzi, Gian Luca Barbruni

The present invention concerns a bodily implantable or probe device and microelectrode fabrication method comprising providing at least one silicon substrate including an electronic device or unit; providing, on a first side of the silicon substrate, at le ...

2024

Simultaneous local sensing of two chemical properties with dual soft probe scanning electrochemical microscopy

Hubert Girault, Andreas Stephan Lesch, Gregorio Bonazza

A new method for the rapid and economic fabrication of dual soft microelectrodes for Soft-Probe-Scanning electrochemical microscopy (Soft-Probe-SECM) and their use for the simultaneous local detection of locally generated species is presented. The process ...

PERGAMON-ELSEVIER SCIENCE LTD2023

Diamond microelectrode arrays for in vitro neuronal recordings

Michele Giugliano

A novel microfabrication technique for microelectrode arrays (MEAs) with a full diamond-cell interface is demonstrated. Boron-doped nano-crystalline diamond (BNCD) is used as a conductive electrode material on metal tracks insulated by intrinsic NCD. MEAs ...

Cambridge Univ Press2017

Artificial spatiotemporal touch inputs reveal complementary decoding in neocortical neurons

Silvestro Micera

Investigations of the mechanisms of touch perception and decoding has been hampered by difficulties in achieving invariant patterns of skin sensor activation. To obtain reproducible spatiotemporal patterns of activation of sensory afferents, we used an art ...

Nature Research2017

Towards brain-on-a-chip : microfluidic and microelectrode array platforms for morphological and electrophysiological observations on the propagation of Alzheimer's disease

Yufei Ren

Since the first compartmentalized neuronal culture described by Robert B. Campenot in 1977, compartmentalized microfluidic devices have been widely used to engineer the cellular environment for cell culture. In previous research by Dr. Anja Kunze, a microf ...

EPFL2016

Whisking-Related Changes in Neuronal Firing and Membrane Potential Dynamics in the Somatosensory Thalamus of Awake Mice

Carl Petersen

The thalamus transmits sensory information to the neocortex and receives neocortical, subcortical, and neuromodulatory inputs. Despite its obvious importance, surprisingly little is known about thalamic function in awake animals. Here, using intracellular ...

Elsevier2015

Cell-type- and activity-dependent extracellular correlates of intracellular spiking

Henry Markram, Rodrigo de Campos Perin, Constantinos Anastassiou

Despite decades of extracellular action potential (EAP) recordings monitoring brain activity, the biophysical origin and inherent variability of these signals remains enigmatic. We performed whole-cell patch recordings of excitatory and inhibitory neurons ...

2015

Finger Probe Array for Topography-Tolerant Scanning Electrochemical Microscopy of Extended Samples

Hubert Girault, Andreas Stephan Lesch, Fernando Cortes Salazar, Dmitry Momotenko, Gunther Wittstock

Scanning electrochemical microscopy with soft microelectrode array probes has recently been used to enable reactivity imaging of extended areas and to compensate sample corrugation perpendicular to the scanning direction. Here, the use of a new type of mic ...

Amer Chemical Soc2014

Synaptic and Cellular Organization of Layer 1 of the Developing Rat Somatosensory Cortex

Shruti Muralidhar

In this thesis, we systematically characterised the circuitry, cellular composition and synaptic connectivity of layer 1 (L1) of the somatosensory cortex of juvenile rats (post natal days 13-16). Electrophysiological and morphological parameters were measu ...

EPFL2013

On chip cellular dielectric spectroscopy : monitoring of glucose effect on erythrocytes membrane and analysis of the physiological role of anthrax toxin receptor in endothelial cells

Ludovica Colella

In the recent years, the development of automated systems for cellular monitoring has been highly promoted in basic biological research as well as in industries and medical diagnostic. Several methods for transduction of cellular signals have been investig ...

EPFL2012

Microfabricated Multimode Bio-interface with High Density Microelectrode Array and Photonic Detectors

Mohssen Moridi

Presently, the cells' electrical activity is measured either by extracellular microelectrode array (MEA) or by microscopic fluorescence imaging methods. The MEA is a non-invasive in vitro technique which allows long-term recording at multicellular level wh ...

EPFL2011

Biosensor microprobe arrays for in vivo monitoring of neurotransmitters

Olivier Frey

Real-time monitoring of neurotransmitters is of utmost importance for understanding the functioning of the brain. Especially L-glutamate and choline play a major role in chemical signalling and are highly involved in cognitive functions such as learning, m ...

EPFL2010

in vivo Electrical Impedance Spectroscopy of Tissue Reaction to Microelectrode Arrays

Philippe Renaud, Arnaud Bertsch, André Mercanzini, Philippe Colin, Jean-Charles Bensadoun

The goal of this experiment was to determine the electrical properties of the tissue reaction to implanted microelectrode arrays. We describe a new method of analyzing electrical impedance spectroscopy data to determine the complex impedance of the tissue ...

2009

Substrate arrays of iridium oxide microelectrodes for in-vitro neuronal interfacing

Philippe Renaud, Henry Markram, Marc Olivier Heuschkel, Michele Giugliano, Shady Didier Gawad

The design of novel bidirectional interfaces for in vivo and in vitro nervous systems is an important step towards future functional neuroprosthetics. Small electrodes, structures and devices are necessary to achieve high-resolution and target-selectivity ...

2009

A benchmark test for a quantitative assessment of simple neuron models

Wulfram Gerstner, Richard Naud, Renaud Jolivet

Several methods and algorithms have recently been proposed that allow for the systematic evaluation of simple neuron models from intracellular or extracellular recordings. Models built in this way generate good quantitative predictions of the future activi ...

Elsevier2008

Internal brain state regulates membrane potential synchrony in barrel cortex of behaving mice

Carl Petersen, James Poulet

Internal brain states form key determinants for sensory perception, sensorimotor coordination and learning. A prominent reflection of different brain states in the mammalian central nervous system is the presence of distinct patterns of cortical synchrony, ...

Nature Publishing Group2008