Publications related to Medical laboratory

Frictional weakening leads to unconventional singularities during dynamic rupture propagation

Marie Estelle Solange Violay, Federica Paglialunga, Mathias Alexandre David Lebihain, François Xavier Thibault Passelègue

Earthquakes i.e. frictional ruptures, are commonly described by singular solutions of shear crack motions. These solutions assume a square root singularity order around the rupture tip and a constant shear stress value behind it, implying scale-independent ...

2024

A Cavity-Microscope for Quantum Simulations with Locally-Controllable All-to-All Interactions

Nick Jacob Sauerwein

This thesis presents the development, construction, and benchmark of an experimental platform that combines cold fermionic 6Li atoms with locally controllable light-matter interactions. To enable local control, a new device, the cavity-microscope, was crea ...

EPFL2024

ERS International Congress 2022: highlights from the Respiratory Clinical Care and Physiology Assembly

Sophie Jacqueline Andrée Betka

It is a challenge to keep abreast of all the clinical and scientific advances in the field of respiratory medicine. This article contains an overview of the laboratory-based science, clinical trials and qualitative research that were presented during the 2 ...

EUROPEAN RESPIRATORY SOC JOURNALS LTD2023

A spatially multiplexed voltammetric magneto-sandwich assay involving Fe3O4/Fe-based metal-organic framework for dual liver cancer biomarkers

Hubert Girault, Milica Jovic

Voltammetric sandwich assays were constructed by integrating capture bioreceptors-conjugated magnetic nanocomposites, namely Fe3O4/MIL-101(Fe)-(NH)(CO)-COOH (FO/MOF) and alkaline phosphatase (ALP)labeled detection antibodies on an eight-well screen-printed ...

ELSEVIER SCIENCE SA2023

Monitoring of Protein and pH Levels in Human Biofluids using FD-SOI Silicon Nanowire Arrays

Luca Capua

Medical research and technological advancements are heading towards tailored healthcare approaches that prioritize individual needs, allowing for more accurate diagnoses, more effective treatments, and better patient outcomes overall. One such approach is ...

EPFL2023

Thermo-hydro-mechanical analysis of the complete lifetime of the bentonite barrier in the FEBEX in-situ test

Lyesse Laloui, Alessio Ferrari, Jose Antonio Bosch Llufriu, Yafei Qiao

The FEBEX test was a large-scale demonstration project for the deep geological disposal concept of nuclear waste involving bentonite seals that lasted 18 years. One of the objectives of the test was to evaluate the capabilities of numerical methods to prov ...

2023

Geotechnical Engineering in the Digital and Technological Innovation Era

The book collects the keynote contributions and the papers presented at the “8th Italian Conference of Researchers in Geotechnical Engineering 2023, CNRIG’23”. The conference was held on July 5–7, 2023, at the University of Palermo (Italy), and it was orga ...

Springer2023

Swelling and shrinkage of partially saturated gas shales: from laboratory tests to an effective stress framework

Jinwoo Kim

Gas shale swelling during hydraulic stimulation is one of the major challenges in unconventional gas development. It is hypothesized that the large volumetric strain upon water imbibition is a consequence of dramatic changes in capillary pressure and disjo ...

EPFL2022

Using Machine Learning to Predict Mortality for COVID-19 Patients on Day 0 in the ICU

Nahal Mansouri, Sahand Jamal Rahi

Rationale: Given the expanding number of COVID-19 cases and the potential for new waves of infection, there is an urgent need for early prediction of the severity of the disease in intensive care unit (ICU) patients to optimize treatment strategies.Objecti ...

FRONTIERS MEDIA SA2022

Rethinking protein aggregation and drug discovery in neurodegenerative diseases: Why we need to embrace complexity?

Hilal Lashuel

More than a century has passed since pathological protein aggregates were first identified in the brains of patients with neurodegenerative diseases (NDDs). Yet, we still do not have effective therapies to treat or slow the progression of these devastating ...

2021

Robustness of In-Laboratory and Daily-Life Gait Speed Measures over One Year in High Functioning 61-to 70-Year-Old Adults

Kamiar Aminian

Introduction: Gait speed is a simple and safe measure with strong predictive value for negative health outcomes in clinical practice, yet in-laboratory gait speed seems not representative for daily-life gait speed. This study aimed to investigate the inter ...

KARGER2021

Real-Time Musculoskeletal Kinematics and Dynamics Analysis Using Marker- and IMU-Based Solutions in Rehabilitation

Dimitar Yuriev Stanev

This study aims to explore the possibility of estimating a multitude of kinematic and dynamic quantities using subject-specific musculoskeletal models in real-time. The framework was designed to operate with marker-based and inertial measurement units enab ...

2021

Capacitive sensor to monitor the level of drug inside an injector pen

Sylvain Paul Fernand Joly

Diabete is a disease which is spreading faster than ever, impacting now a larger population. Patients suffering from this disease need the injection of insulin to control extracellular sugar levels. Pharmaceutical companies developed injector pens to allow ...

EPFL2021

Review of control strategies for lower-limb exoskeletons to assist gait

Auke Ijspeert, Mohamed Bouri, Ali Reza Manzoori, Romain Pierre François Baud

Background Many lower-limb exoskeletons have been developed to assist gait, exhibiting a large range of control methods. The goal of this paper is to review and classify these control strategies, that determine how these devices interact with the user. Met ...

BioMed Central2021

Institutional ELN/LIMS deployment Highly customizable ELN/LIMS platform as a cornerstone of digital transformation for life sciences research institutes

Nicolas Argento

The systematic recording and management of experimental data in academic life science research remains an open problem. EPFL engaged in a program of ELN/LIMS deployment 6 years ago, encountering a host of fundamental questions at the institutional level an ...

2020

Nanoparticle-enhanced Imaging Based Plasmonic Biosensor

Alexander Belushkin

Efficient medical care fundamentally relies on the ability to provide a timely and accurate diagnosis. Thanks to advances in biomedical research, specific molecules called diagnostic molecular biomarkers have been discovered in the human body that help ind ...

EPFL2020

Quality Evaluation Of Static Point Clouds Encoded Using MPEG Codecs

Touradj Ebrahimi, Evangelos Alexiou

This paper presents a quality evaluation study of point cloud codecs that have been recently standardised by the MPEG committee. In particular, a subjective experiment to assess their performance in terms of bitrate against visual quality is designed and r ...

IEEE2020

High Precision Capacitive Moisture Sensor for Polymers: Modeling and Experiments

Marco Mattavelli, Jean-Michel Sallese, Catherine Dehollain, Diego Ruben Barrettino

In this work a high precision capacitive moisture sensor for polymers was designed and fabricated. The device is part of a compact, fast, and economic moisture analyzer capable of reaching a similar precision than commercial moisture analyzers based on the ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2020

CMOS-Based Readout and Control Electronics for Microgrippers

Marco Mattavelli, Diego Ruben Barrettino

This paper presents the design of an application-specific integrated circuit (ASIC) with all the necessary electronic blocks to read out and control Conjugate Surfaces Flexure Hinge (CSFH) microgrippers. The ASIC was fabricated using a high-voltage 0.35 mu ...

IEEE2020

HISTOBREAST, a collection of brightfield microscopy images of Haematoxylin and Eosin stained breast tissue

Tiberiu Totu

Modern histopathology workflows rely on the digitization of histology slides. The quality of the resulting digital representations, in the form of histology slide image mosaics, depends on various specific acquisition conditions and on the image processing ...

2020