Explores DNA repair mechanisms, including BER, MMR, NER, and repair of double-strand breaks, as well as the impact of UV-induced lesions and resistance to PARP inhibitors.
Covers mutations, classification, causes, and repair mechanisms of DNA, including spontaneous and induced mutations, replication errors, and DNA damage.
Explores the applications of CRISPR-Cas in genome editing, focusing on engineering bacterial genomes, curing genetic diseases, guide RNA simplicity, Cas9 specificity, DNA damage mechanisms, and base editing.