Publications related to Hemiparesis

Context-Aware Monitoring of Hand Motor Primitives in Daily Life Activities: A Pathway to Objectively Assess Rehabilitation of Patients with Upper-Limb Neurological Impairment

The hands, our silent performers in daily life, face overwhelming challenges when neurological impairments disrupt the simple tasks that compose our daily symphony. This thesis unveils a comprehensive framework for the objective monitoring of upper-limb re ...

EPFL2024

Immediate effect of ankle exoskeleton on spatiotemporal parameters and center of pressure trajectory after stroke

Silvestro Micera, Mohamed Bouri, Solaiman Shokur, Mouhamed Zorkot

Gait impairments is a common condition in post-stroke subjects. We recently presented a wearable ankle exoskeleton called G-Exos, which showed that the device assisted in the ankle's dorsiflexion and inversion/reversion movements. The aim of the current pi ...

IEEE2023

Neurophysiological underpinnings of an intensive protocol for upper limb motor recovery in subacute and chronic stroke patients

Silvestro Micera, Matteo Vissani, Michael Lassi

ABS T R A C T BACKGROUND: Upper limb (UL) motor impairment following stroke is a leading cause of functional limitations in activities of daily living. Robot-assisted therapy supports rehabilitation, but how its efficacy and the underlying neural mechanism ...

Edizioni Minerva Medica2023

Longitudinal evaluation of the mechanisms supporting post-stroke motor recovery using TMS-EEG coupling

Andéol Geoffroy Cadic-Melchior

Stroke is the main source of long-lasting disability, affecting dominantly motor functions. The extent and course of recovery are highly heterogeneous between patients, with a minority of patients fully recovering from their initial impairments, leaving 85 ...

EPFL2023

Movement-Related Cortical Potentials in Embodied Virtual Mirror Visual Feedback

Gangadhar Garipelli, Tamara Rossy

Background: Mirror therapy is thought to drive interhemispheric communication, resulting in a balanced activation. We hypothesized that embodied virtual mirror visual feedback (VR-MVF) presented on a computer screen may produce a similar activation. In thi ...

FRONTIERS MEDIA SA2021

Reply to: “1.5 Dissociation” of somatoparaphrenia for the upper limb and neglect for the lower limb following a thalamic stroke presenting as flaccid hemiparesis: rehabilitation applications and neuroscience implications

Olaf Blanke

This interesting case study reports on a patient who subsequent to a right thalamic hematoma developed a left hemiparesis, left extrapersonal and personal hemineglect and somatoparaphrenia, but only for the arm not the leg. It is not specifically mentioned ...

2019

Neurotechnology-aided interventions for upper limb motor rehabilitation in severe chronic stroke

José del Rocio Millán Ruiz, Silvestro Micera, Friedhelm Christoph Hummel, Maximilian Jonas Wessel, Martina Coscia, John Donoghue

Upper limb motor deficits in severe stroke survivors often remain unresolved over extended time periods. Novel neurotechnologies have the potential to significantly support upper limb motor restoration in severely impaired stroke individuals. Here, we revi ...

2019

Wearable technology in stroke rehabilitation: towards improved diagnosis and treatment of upper-limb motor impairment

Friedhelm Christoph Hummel, Pablo Maceira Elvira, Traian Popa, Anne-Christine Schmid

Stroke is one of the main causes of long-term disability worldwide, placing a large burden on individuals and society. Rehabilitation after stroke consists of an iterative process involving assessments and specialized training, aspects often constrained by ...

BioMed Central2019

Electromyographic indices of muscle fatigue of a severely paralyzed chronic stroke patient undergoing upper limb motor rehabilitation

Modern approaches to motor rehabilitation of severe upper limb paralysis in chronic stroke decode movements from electromyography for controlling rehabilitation orthoses. Muscle fatigue is a phenomenon that influences these neurophysiological signals and m ...

IEEE2019

Restoring Motor Functions After Stroke: Multiple Approaches and Opportunities

Friedhelm Christoph Hummel, Estelle Emeline Raffin

More than 1.5 million people suffer a stroke in Europe per year and more than 70% of stroke survivors experience limited functional recovery of their upper limb, resulting in diminished quality of life. Therefore, interventions to address upper-limb impair ...

2018

Evaluating upper limb impairments in multiple sclerosis by exposure to different mechanical environments

Martina Coscia

Multiple sclerosis is a chronic, autoimmune and neurodegenerative disease affecting multiple functional systems and resulting in motor impairments associated with muscle weakness and lack of movement coordination. We quantified upper limb motor deficits wi ...

Nature Research2018

Advantages of soft subdural implants for the delivery of electrochemical neuromodulation therapies to the spinal cord

Stéphanie Lacour, Marco Capogrosso, Grégoire Courtine, Eduardo Martin Moraud, Pavel Musienko, Ivan Rusev Minev, Nikolaus Wenger, Jérôme Gandar, Polina Shkorbatova, Nathan Antoine Greiner

Objective. We recently developed soft neural interfaces enabling the delivery of electrical and chemical stimulation to the spinal cord. These stimulations restored locomotion in animal models of paralysis. Soft interfaces can be placed either below or abo ...

2018

Brain-computer interfaces for post-stroke motor rehabilitation: a meta-analysis

José del Rocio Millán Ruiz, Gangadhar Garipelli

Brain‐computer interfaces (BCIs) can provide sensory feedback of ongoing brain oscillations, enabling stroke survivors to modulate their sensorimotor rhythms purposefully. A number of recent clinical studies indicate that repeated use of such BCIs might tr ...

2018

Electrically Assisted Movement Therapy in Chronic Stroke Patients With Severe Upper Limb Paresis: A Pilot, Single-Blind, Randomized Crossover Study

José del Rocio Millán Ruiz, Andrea Biasiucci, Silvio Ionta, Andrea Maesani, Stephanie Clarke

Objective To evaluate the effects of electrically assisted movement therapy (EAMT) in which patients use functional electrical stimulation, modulated by a custom device controlled through the patient's unaffected hand, to produce or assist task-specific up ...

Elsevier2017

Increasing upper limb training intensity in chronic stroke using embodied virtual reality: a pilot study

Olaf Blanke, José del Rocio Millán Ruiz, Andrea Serino, Gangadhar Garipelli, Thomas Schmidlin, Odile Hélène Chevalley

Background: Technology-mediated neurorehabilitation is suggested to enhance training intensity and therefore functional gains. Here, we used a novel virtual reality (VR) system for task-specific upper extremity training after stroke. The system offers inte ...

BioMed Central2017

Measuring upper limb function in children with hemiparesis with 3D inertial sensors

Kamiar Aminian, Cyntia Duc, Farzin Dadashi, Fabien Massé

Upper limb assessments in children with hemiparesis rely on clinical measurements, which despite standardization are prone to error. Recently, 3D movement analysis using optoelectronic setups has been used to measure upper limb movement, but generalization ...

Springer Verlag2017

Cortico-reticulo-spinal circuits mediate functional recovery after spinal cord contusion

Léonie Asboth

After a spinal cord injury (SCI), only half of affected individuals regain voluntary control of leg movements below the level of the lesion. Anatomical, electrophysiological and imaging data revealed that even the most severe forms of SCI usually spare a s ...

EPFL2017

Model-based variables for the kinematic assessment of upper-extremity impairments in post-stroke patients

Silvestro Micera, Elvira Pirondini

Background: Common scales for clinical evaluation of post-stroke upper-limb motor recovery are often complemented with kinematic parameters extracted from movement trajectories. However, there is no a general consensus on which parameters to use. Moreover, ...

BioMed Central2016

Robot-assisted gait training improves motor performances and modifies Motor Unit firing in post-stroke patients

Silvestro Micera

Background. Robotics and related technologies are realizing their promise to improve the delivery of rehabilitation therapy but the mechanism by which they enhance recovery is still unknown. The electromechanical-driven gait orthosis Lokomat has demonstrat ...

Edizioni Minerva Medica2015

Activating the motor system through action observation: is this an efficient approach in adults and children?

Michela Bassolino

Observing an action performed by another person to learn a new movement is a frequent experience in adult daily life, such as in sports. However, it is an especially common circumstance during the development of motor skills in childhood. Studies on health ...

Wiley-Blackwell2015