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Related publications (30)

Segregated Algorithms for the Numerical Simulation of Cardiac Electromechanics in the Left Human Ventricle

Alfio Quarteroni

We propose and numerically assess three segregated ( partitioned) algorithms for the numerical solution of the coupled electromechanics problem for the left human ventricle. We split the coupled problem into its core mathematical models and we proceed to t ...

SPRINGER INTERNATIONAL PUBLISHING AG2020

Endothelial extracellular vesicles contain protective proteins and rescue ischemia-reperfusion injury in a human heart-on-chip

Maartje Martina Cornelia Bastings

Extracellular vesicles (EVs) derived from various stem cell sources induce cardioprotective effects during ischemia-reperfusion injury (IRI). These have been attributed mainly to the antiapoptotic, proangiogenic, microRNA (miRNA) cargo within the stem cell ...

AMER ASSOC ADVANCEMENT SCIENCE2020

Active Force Generation in Cardiac Muscle Cells: Mathematical Modeling and Numerical Simulation of the Actin-Myosin Interaction

Alfio Quarteroni, Luca Dede', Francesco Regazzoni

Cardiac in silico numerical simulations are based on mathematical models describing the physical processes involved in the heart function. In this review paper, we critically survey biophysically-detailed mathematical models describing the subcellular mech ...

SPRINGER SINGAPORE PTE LTD2021

Virtual High-Framerate Microscopy of the Beating Heart via Sorting of Still Images

Michael Stefan Daniel Liebling, Olivia Mariani

Microscopy of the beating heart in embryos provides key insights for the study of its development. However, achieving a sufficiently high framerate is difficult with conventional cameras. Here, we present a method to reconstruct an image sequence covering ...

Idiap2019

Cylindrical Dielectric Elastomer Actuator for Cardiac Assist Device

Jonathan André Jean-Marie Chavanne

This work has been triggered because of the need for a new way to relieve the heart. Current solutions are based on invasive systems. The main problem of such assistance is infectious risks. State of the art to define an alternative has allowed highlightin ...

EPFL2019

Characterization of a radial cylindrical spring using an electromechanical test bench

Yves Perriard, Yoan René Cyrille Civet, Jonathan André Jean-Marie Chavanne, David Moser

The Center for Artificial Muscles of EPFL in Neuchâtel focuses his research on designing a less invasive cardiac assist device based on a dielectric elastomer actuator. The idea is to place a ring around the aorta and activate it to help failing heart pump ...

2019

A monolithic algorithm for the simulation of cardiac electromechanics in the human left ventricle

Alfio Quarteroni, Luca Dede', Antonello Gerbi

In this paper, we propose a monolithic algorithm for the numerical solution of the electromechanics model of the left ventricle in the human heart. Our coupled model integrates the monodomain equation with the Bueno-Orovio minimal model for electrophysiolo ...

2018

Method and Device for Non-Invasive Blood Pressure Measurement

David Atienza Alonso, Francisco Javier Rincon Vallejos, Srinivasan Murali, Alair Dias Junior

A system for measuring blood pressure of a user that comprises an ElectroCardioGram (ECG) circuit with at least two ECG electrodes configured to obtain an electrical activity of a heart of the user by measuring the electrical signals detected at the at lea ...

2017

A Variable Stiffness Catheter Controlled with an External Magnetic Field

Dario Floreano, Alice Tonazzini

Remote magnetic navigation of catheters is a technique used to perform radiofrequency ablation of heart tissue in order to treat cardiac arrhythmias. The flexible magnetic catheters used in this context are in some cases not sufficiently dexterous to navig ...

IEEE2017

Isogeometric approximation of cardiac electrophysiology models on surfaces: An accuracy study with application to the human left atrium

Alfio Quarteroni, Luca Dede', Toni Mikael Lassila, Alessandro Samuele Patelli, Andrea Bartezzaghi

We consider Isogeometric Analysis in the framework of the Galerkin method for the spatial approximation of cardiac electrophysiology models defined on NURBS surfaces; specifically, we perform a numerical comparison between basis functions of degree p >= 1 ...

Elsevier2017

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