Publications related to Regulation

Kidney-Specific Membrane-Bound Serine Proteases CAP1/Prss8 and CAP3/St14 Affect ENaC Subunit Abundances but Not Its Activity

The serine proteases CAP1/Prss8 and CAP3/St14 are identified as ENaC channel-activating proteases in vitro, highly suggesting that they are required for proteolytic activation of ENaC in vivo. The present study tested whether CAP3/St14 is relevant for rena ...

MDPI2023

Improved Network-Calculus Nodal Delay-Bounds in Time-Sensitive Networks

Jean-Yves Le Boudec, Eleni Stai, Ehsan Mohammadpour

In time-sensitive networks, bounds on worst-case delays are typically obtained by using network calculus and assuming that flows are constrained by bit-level arrival curves. However, in IEEE TSN or IETF DetNet, source flows are constrained on the number of ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2023

Politics of Urban Planning : The Making and Unmaking of the Mumbai Development Plan 2014-2034

Luca Giovanni Pattaroni

This book offers an interdisciplinary and dynamic account of the politicization of urban planning in Mumbai, India. It presents a unique perspective on the tensions and conflicts pervading the development and regulation of contemporary cities in the wider ...

Springer2022

Nine recommendations for the governance of AI systems

Marie-Valentine Renée Agnès Florin

Some governance functions traditionally performed by humans are increasingly informed and sometimes automatically executed by machine learning algorithms (governance by machine learning) to benefit society. Therefore, it is necessary to think also about th ...

EPFL2022

Essays in Banking and Financial Regulation

Susanne Johanna Petronella Léonie Vissers

This thesis examines how banks choose their optimal capital structure and cash reserves in the presence of regulatory measures. The first chapter, titled Bank Capital Structure and Tail Risk, presents a bank capital structure model in which bank assets ...

EPFL2021

Price-based regulation of oligopolistic markets under discrete choice models of demand

Michel Bierlaire, Virginie Janine Camille Lurkin, Stefano Bortolomiol

We propose a framework to find optimal price-based policies to regulate markets characterized by oligopolistic competition and in which consumers make a discrete choice among a finite set of alternatives. The framework accommodates general discrete choice ...

2022

Fluid flow-induced left-right asymmetric decay of Dand5 mRNA in the mouse embryo requires a Bicc1-Ccr4 RNA degradation complex

Daniel Constam, Benjamin Marcel Daniel Rothé

Molecular left-right (L-R) asymmetry is established at the node of the mouse embryo as a result of the sensing of a leftward fluid flow by immotile cilia of perinodal crown cells and the consequent degradation of Dand5 mRNA on the left side. We here examin ...

Nature Portfolio2021

Die multiplen Rechenschaftspflichten von öffentlichen Unternehmen gegenüber dem Staat - Eine empirische Typologie der Entstehung und des Managements inkohärenter Erwartungen

Fabian Liechti

State-owned enterprises (SOEs) provide important services such as power supply, postal services and public transportation. In doing this, SOEs operate at the intersection of political/regulatory and economic expectations. Therefore, SOEs are commonly consi ...

EPFL2019

Three Problems of Liquidity under Asymmetric Information

Sylvain Jean Pascal Carré

This thesis develops models for three problems of liquidity under asymmetric information. In the chapter "Disclosures, Rollover Risk, and Debt Runs" I build a model of dynamic debt runs without perfect information in order to understand the impact of asset ...

EPFL2019

A Theory of Traffic Regulators for Deterministic Networks With Application to Interleaved Regulators

Jean-Yves Le Boudec

We introduce Pi-regulation, a new definition of traffic regulation which extends both the arrival curves of network calculus and Chang's max-plus g-regulation, and also includes new types of regulation, such as packet rate limitations. We provide a new exa ...

2018

A roadmap for the development of precision medicine

Marie-Valentine Renée Agnès Florin, Gérard Escher

The purpose of the roadmap proposed by IRGC is to recommend a structured process that organisations can follow in their transition towards the development of precision medicine. The process is adaptable, and each organisation should further develop it to a ...

International Risk Governance Center (IRGC)2017

Transatlantic Patterns of Risk Regulation: Implications for International Trade and Cooperation

Marie-Valentine Renée Agnès Florin

This report presents a study commissioned by the European Parliament to compare regulatory standards in the EU and the US in four key sectors (food safety, automobiles, chemicals, and pharmaceuticals), chosen for their relevance both to consumer protection ...

International Risk Governance Council2017

Meta-analysis of real-time fMRI neurofeedback studies using individual participant data: How is brain regulation mediated?

Dimitri Nestor Alice Van De Ville, Rotem Roza Kopel, Kirsten Emmert

An increasing number of studies using real-time fMRI neurofeedback have demonstrated that successful regulation of neural activity is possible in various brain regions. Since these studies focused on the regulated region(s), little is known about the targe ...

Elsevier2016

Regulatory Institutions and Governance Costs : The Case of the Postal Sector

Martin Maegli

In recent decades, the European postal industry has undergone profound reforms, which aim to promote competition while simultaneously maintaining a high level of universal services for consumers. It is often put forth that market opening and the emergence ...

EPFL2012

Integration of sustainability issues into the design process of a temporary event infrastructure

Loïc Vivien Fumeaux, Emmanuel Rey

Within the frame of temporary events, having recourse to the model of the tent corresponds to usual experiences. When the model offers advantages of fast assembly and certain flexibility, it has some significant disadvantages at the same time, especially r ...

2012

Regulatory Uncertainty and Nonmarket Capabilities : An Investigation of the Electricity Generation Sector

Bastian Wolfgang Schwark

In 2005, the Economist Intelligence Unit conducted a survey with Chief Risk Officers worldwide across all industries and asked about the biggest threat to their businesses. Interestingly, regulatory risk ranked first. It dominated all other types of risk, ...

EPFL2011

Regulation of PGC-1 alpha, a nodal regulator of mitochondrial biogenesis

Johan Auwerx, Pablo Jose Fernandez Marcos

Mechanisms responsible for energy management in the cell and in the whole organism require a complex network of transcription factors and cofactors. Peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1 alpha) has emerged as a master ...

2011

Regulatory Governance Costs in Network Industries: Observations in Postal Regulation

Matthias Finger

The various actors in the regulated industries relate to each other within a broader institutional framework, i.e., by way of formal and informal rules. An important role in the implementation of liberalization processes is given to regulation and thus to ...

2010

Postal Markets and Electronic Substitution: What is the Impact of Intermodal Competition on Regulatory Practices and Institutions

Martin Maegli

This increasing convergence between postal products and telecom applications is a new phenomenon in the communications environment: Postal operators provide new services on telecom infrastructures, telecom infrastructures are likely to substitute last mile ...

2010

Postal Markets and Electronic Substitutions: What is the Impact of Intermodal Competition on Regulatory Practices and Institutions

Martin Maegli

This increasing convergence between postal products and telecom applications is a new phenomenon in the communications environment: Postal operators provide new services on telecom infrastructures, telecom infrastructures are likely to substitute last mile ...

2010