Publications related to Unilateral hearing loss

Unraveling behavior and cortical signals to guide the development of soft neuroprostheses for auditory restoration and spreading depolarization

Neuroprostheses have been used clinically for decades, to help restore or preserve brain functions, when pharmaceutical treatments are inefficient. Although great progress in the field has been made over the years to interface with the nervous system, surf ...

EPFL2024

Long-Term Hearing Outcome After Radiosurgery for Vestibular Schwannoma: A Systematic Review and Meta-Analysis

Constantin Tuleasca, Adrien Jean Régis Maurice Hilaire

BACKGROUND: Stereotactic radiosurgery (SRS) is one of the main treatment options in the management of small to medium size vestibular schwannomas (VSs), because of high tumor control rate and low cranial nerves morbidity. Series reporting long-term hearing ...

LIPPINCOTT WILLIAMS & WILKINS2023

Bone conduction facilitates self-other voice discrimination

Olaf Blanke, Nathan Quentin Faivre, Oliver Alan Kannape, Pavo Orepic

One's own voice is one of the most important and most frequently heard voices. Although it is the sound we associate most with ourselves, it is perceived as strange when played back in a recording. One of the main reasons is the lack of bone conduction tha ...

2023

Get More for Less in Decentralized Learning Systems

Anne-Marie Kermarrec, Rafael Pereira Pires, Akash Balasaheb Dhasade, Rishi Sharma, Milos Vujasinovic, Jeffrey Wigger

Decentralized learning (DL) systems have been gaining popularity because they avoid raw data sharing by communicating only model parameters, hence preserving data confidentiality. However, the large size of deep neural networks poses a significant challeng ...

IEEE2023

Human Head Yaw Estimation based on Two 3-axis Accelerometers

Hervé Lissek, Gilles André Courtois, Vincent Pierre Olivier Grimaldi

The estimation of the orientation of an object, and a human head in particular, can be defined by the Euler angles: the yaw, pitch and roll. The robust and drift-free estimation of those angles is usually achieved with the data from several sensors such as ...

2022

Auditory externalization of a remote microphone signal

Vincent Pierre Olivier Grimaldi

A remote microphone (RM) system can be used in combination with wearable binaural communication devices, such as hearing aids (HAs), to improve speech intelligibility. Typically, a speaker is equipped with a body-worn microphone which enables to pick up th ...

EPFL2022

Lower glutamate and GABA levels in auditory cortex of tinnitus patients: a 2D-JPRESS MR spectroscopy study

Thorsten Kleinjung, Patrick Karl Alois Neff

We performed magnetic resonance spectroscopy (MRS) on healthy individuals with tinnitus and no hearing loss (n = 16) vs. a matched control group (n = 17) to further elucidate the role of excitatory and inhibitory neurotransmitters in tinnitus. Two-dimensio ...

Nature Research2022

Conformable neural interfaces : from engineering stretchability at the micro-scale to translational applications

Florent-Valéry Coen

Recently, flexible and soft bioelectronic interfaces have been proposed as a solution to improve existing neural interfaces that currently present mechanical mismatch with the soft tissue. These are devices fabricated with thin polymeric or elastomeric bac ...

EPFL2022

Fabrication and validation of an intraneural interface tailored for optic nerve stimulation

Eleonora Borda

Technological progress in materials science and microengineering along with new discoveries in neuroscience have contributed to restore lost or impaired sensory functions by closely interfacing with the nervous system. Electronic devices have begun to be i ...

EPFL2022

Repeat stereotactic radiosurgery for progressive vestibular schwannomas after previous radiosurgery: a systematic review and meta-analysis

Constantin Tuleasca, Adrien Jean Régis Maurice Hilaire

Vestibular schwannomas (VS) are slow-growing intracranial extraaxial benign tumors, developing from the vestibular part of the eight cranial nerves. Stereotactic radiosurgery (SRS) has now a long-term scientific track record as first intention treatment fo ...

SPRINGER2021

Variants in USP48 encoding ubiquitin hydrolase are associated with autosomal dominant non-syndromic hereditary hearing loss

Nicolas Jean Philippe Guex

Non-Syndromic Hereditary Hearing Loss (NSHHL) is a genetically heterogeneous sensory disorder with about 120 genes already associated. Through exome sequencing (ES) and data aggregation, we identified a family with six affected individuals and one unrelate ...

Oxford University Press2021

EEG Spatiotemporal Patterns Underlying Self-other Voice Discrimination

Olaf Blanke, Pavo Orepic, Sixto Luis Alcoba Banqueri, Giannina Rita Iannotti, Thomas Koenig

There is growing evidence showing that the representation of the human “self” recruits special systems across different functions and modalities. Compared to self-face and self-body representations, few studies have investigated neural underpinnings specif ...

2021

Dissecting self-voice perception: From bone conduction to robotically-induced self-other voice misattribution in healthy listeners

Pavo Orepic

Inspired by the prominent theory suggesting that auditory-verbal hallucinations (AVH) - the sensation of hearing voices without present speakers - arise as misattribution of inner speech towards external agents, my thesis revolved around self-voice percept ...

EPFL2020

Smaller, Faster & Lighter KNN Graph Constructions

Rachid Guerraoui, Anne-Marie Kermarrec, Olivier Ruas

We propose GoldFinger, a new compact and fast-to-compute binary representation of datasets to approximate Jaccard’s index. We illustrate the effectiveness of GoldFinger on the emblematic big data problem of K-Nearest-Neighbor (KNN) graph construction and s ...

2020

Breathing affect self-other voice discrimination in a bodily state with increased otherness

Olaf Blanke, Nathan Quentin Faivre, Giulio Rognini, Hyeongdong Park, Pavo Orepic

A growing number of studies have focused on identifying cognitive processes that are modulated by interoceptive signals. Here we investigated whether interoception affects self-processing, by assessing changes in self-voice perception as a function of resp ...

2020

Perception of Auditory Distance in Normal-Hearing and Moderate-to-Profound Hearing-Impaired Listeners

Hervé Lissek, Gilles André Courtois, Vincent Pierre Olivier Grimaldi

The auditory system allows the estimation of the distance to sound-emitting objects using multiple spatial cues. In virtual acoustics over headphones, a prerequisite to render auditory distance impression is sound externalization, which denotes the percept ...

2019

Inner ear cellular imaging through scattering bone

Demetri Psaltis, Marilisa Romito

Inner ear imaging is important for the assessment of hearing disorders. A major cause of hearing loss is the damage to the sensory hair cells, which are located inside the cochlea, a spiral-shaped bone in the inner ear. Imaging of intracochear hair cells i ...

SPIE-INT SOC OPTICAL ENGINEERING2019

Delivery of CRISPR/Cas9 using AAV-PHP.B in the inner ear leads to allele-specific inactivation of the mutated Tmc1 allele and protects auditory function in Beethoven mice

Bernard Schneider, Paola Andrea Solanes Vega, Sofia Carmen Suzanne Spataro

Hearing Loss (HL) is the most prevalent sensorineural disorder, affecting 360 million people worldwide. As genetic causes lead to 50% of pre-lingual deafness, gene therapy is considered as a potential therapeutic strategy. Mutations in the TMC1 gene are li ...

MARY ANN LIEBERT, INC2019

Fingerprinting Big Data: The Case of KNN Graph Construction

Rachid Guerraoui, Anne-Marie Kermarrec, Olivier Ruas

We propose fingerprinting, a new technique that consists in constructing compact, fast-to-compute and privacy-preserving binary representations of datasets. We illustrate the effectiveness of our approach on the emblematic big data problem of K-Nearest-Nei ...

2019

Circadian Regulation of Cochlear Sensitivity to Noise by Circulating Glucocorticoids

Frédéric Bruno Martin Gachon, Benjamin Dieter Weger

The cochlea possesses a robust circadian clock machinery that regulates auditory function. How the cochlear clock is influenced by the circadian system remains unknown. Here, we show that cochlear rhythms are system driven and require local Bmal1 as well a ...

2019