Publications related to Conservation genetics

The SNP-Based Profiling of Montecristo Feral Goat Populations Reveals a History of Isolation, Bottlenecks, and the Effects of Management

The Montecristo wild goat is an endangered feral population that has been on the homonymous island in the Tuscan Archipelago since ancient times. The origins of Montecristo goats are still debated, with authors dating their introduction either back to Neol ...

MDPI2022

Naming CHO cells for bio-manufacturing: Genome plasticity and variant phenotypes of cell populations in bioreactors question the relevance of old names

Florian Maria Wurm

Chinese Hamster Ovary [CHO] cells are the workhorse for production of modern biopharmaceuticals. They are however immortalized cells with a high propensity for genetic change. Judging from published culture records, CHO cell populations have undergone hund ...

2021

The Least Cost Path From Landscape Genetics to Landscape Genomics: Challenges and Opportunities to Explore NGS Data in a Spatially Explicit Context

Stéphane Joost

Ecosystems are the stage on which the play of evolution is acted. Inferring evolutionary processes from the spatial and temporal genetic patterns they produce in populations is challenging because ecosystems are highly complex, spatially structured, and te ...

2018

Two sides of the same coin: A population genetics perspective on lethal mutagenesis and mutational meltdown

Jeffrey David Jensen, Claudia Bank, Sebastian Matuszewski, Nicky Louise Ormond

The extinction of RNA virus populations upon application of a mutagenic drug is frequently referred to as evidence for the existence of an error threshold, above which the population cannot sustain the mutational load. To explain the extinction process aft ...

Oxford Univ Press2017

Persistence of butterfly populations in fragmented habitats along urban density gradients: motility helps

Stéphane Joost, Estelle Rochat, Ivo Widmer

In a simulation study of genotypes conducted over 100 generations for more than 1600 butterfly’s individuals, we evaluate how the increase of anthropogenic fragmentation and reduction of habitat size along urbanisation gradients (from 7% to 59% of impervio ...

Nature Publishing Group2017

The evolution of phenotypic plasticity under global change

Emma Mary Gibbin

Marine ecosystems are currently in a state of flux, with ocean warming and acidification occurring at unprecedented rates. Phenotypic plasticity underpins acclimatory responses by shifting the mean phenotype in a population, which may buffer the negative e ...

Springer Nature2017

Coalescent inferences in conservation genetics: should the exception become the rule?

Valeria Montano

Genetic estimates of effective population size (Ne) are an established means to develop informed conservation policies. Another key goal to pursue the conservation of endangered species is keeping the connectivity across fragmented environments, to which g ...

Royal Soc2016

Assessing Recent Selection and Functionality at Long Noncoding RNA Loci in the Mouse Genome

Anamaria Necsulea

Long noncoding RNAs (lncRNAs) are one of the most intensively studied groups of noncoding elements. Debate continues over what proportion of lncRNAs are functional or merely represent transcriptional noise. Although characterization of individual lncRNAs h ...

Oxford Univ Press2015

Multi-scale landscape genomic models : the role of very high resolution digital elevation models in evolutionary biology

Kevin Leempoel

Environmental heterogeneity is one of the main actors of biodiversity and species adaptation as it exerts a selective pressure on observable characteristics of living organisms. Consequently, local adaptation favours certain genetic variants and, by doing ...

EPFL2015

Neutral and Adaptive Drivers of Microgeographic Genetic Divergence within Continuous Populations: The Case of the Neotropical Tree Eperua falcata (Aubl.)

Matthieu Foll

Background In wild plant populations, genetic divergence within continuous stands is common, sometimes at very short geographical scales. While restrictions to gene flow combined with local inbreeding and genetic drift may cause neutral differentiation amo ...

Public Library of Science2015

Three-dimensional microstructural mapping of poisoning phases in the Neodymium Nickelate solid oxide fuel cell cathode

Jan Van Herle, Josef Andreas Schuler, Henning Lübbe, Jun Wang

Nd-Nickelate (NNO), Nd1.95NiO4+delta, an alternative solid oxide fuel cell cathode material, has been imaged and mapped in 3D using synchrotron-based x-ray nanotomography. The NNO cathode material, which suffered from silicon contamination during fabricati ...

Elsevier Science Bv2013

A multiscale landscape genomics analytical framework to identify local adaptive variation in the Buckler Mustard

Stéphane Joost, Kevin Leempoel

The question of finding an appropriate scale to study adaptation emerged only recently in landscape genomics, while in landscape ecology its components (extent and resolution or grain) have been addressed in many papers. In fact, in landscape genetics only ...

2013

Relatedness and scale dependency in very high resolution digital elevation models derivatives

Stéphane Joost, Kevin Leempoel

In the field of landscape genetics, environmental variables are needed to assess the influence of the environment on the spatial distribution of the genetic information of animals or plants. However, measuring variables (e.g. temperature, precipitation) at ...

Lulu.com2012

Promoting collaboration between livestock and wildlife conservation genetics communities

Stéphane Joost, Pierre Taberlet

The collaboration between livestock and wildlife conservation genetics communities has the potential to help promote shared priorities, with respect to emerging technologies and new analytical approaches such as next generation sequencing incorporating ada ...

Springer Netherlands2011

Perspectives on the use of landscape genetics to detect genetic adaptive variation in the field

Stéphane Joost

Understanding the genetic basis of species adaptation in the context of global change poses one of the greatest challenges of this century. Although we have begun to understand the molecular basis of adaptation in those species for which whole genome seque ...

Wiley-Blackwell2010

The Interplay between Cytidine Deaminases, HIV and Domesticated Genetic Parasites

"There is more virus in us than us in us". John Coffin's famous sentence illustrates that particular nucleic acid sequences related to exogenous viruses, called retrotransposons, constitute almost half of the human genome and largely exceeds the amount of ...

EPFL2010

The geographical dimension of genetic diversity : a GIScience contribution for the conservation of animal genetic resources

Stéphane Joost

In its natural framework, genetic information is embedded within a geographic context. Plants and animals are directly influenced by the specific characteristics of their surrounding environment. Therefore, spatial information is a potentially important el ...

EPFL2006