Publications related to Post-traumatic seizure

Resource-Efficient Continual Learning for Personalized Online Seizure Detection

David Atienza Alonso, Giovanni Ansaloni, José Angel Miranda Calero, Jonathan Dan, Amirhossein Shahbazinia, Flavio Ponzina

Epilepsy, a major neurological disease, requires careful diagnosis and treatment. However, the detection of epileptic seizures remains a significant challenge. Current clinical practice relies on expert analysis of EEG signals, a process that is time-consu ...

IEEE2024

Hardware Implementation of Digital Signal Processing Algorithms for Programmable Epilepsy Control Systems

Keyvan Farhang Razi

Epilepsy is a common chronic neurological disorder that causes recurring seizures and affects more than 50 million people worldwide. Implantable medical devices (IMDs) are regarded as effective tools to cure patients who suffer from refractory epilepsy. Se ...

EPFL2023

Prediction of post-stroke motor recovery benefits from measures of sub-acute widespread network damages

Dimitri Nestor Alice Van De Ville, Maria Giulia Preti, Elvira Pirondini, Cyprien Alban Félicien Rivier

Rivier et al. report that global measures of brain connectivity estimated by introducing virtual lesions in healthy structural connectomes significantly increase the accuracy of motor recovery prediction in stroke patients when added to focal and clinical ...

OXFORD UNIV PRESS2023

How I became myself after merging with a computer: Does human-machine symbiosis raise human rights issues?

Marcello Ienca

Novel usages of brain stimulation combined with artificially intelligent (AI) systems promise to address a large range of diseases. These new conjoined technologies, such as brain-computer interfaces (BCI), are increasingly used in experimental and clinica ...

ELSEVIER SCIENCE INC2023

Approximate Zero-Crossing: A new interpretable, highly discriminative and low-complexity feature for EEG and iEEG seizure detection

David Atienza Alonso, Tomas Teijeiro Campo, Una Pale, Renato Zanetti

Objective: Long-term monitoring of people with epilepsy based on electroencephalography (EEG) and intracranial EEG (iEEG) has the potential to deliver key clinical information for personalised epilepsy treatment. More specifically, in outpatient settings, ...

2022

Cerebral Metabolic Dysfunction at the Acute Phase of Traumatic Brain Injury Correlates with Long-Term Tissue Loss

Adriano Bernini, Ricardo Alberto Corredor Jerez, Neil Graham

Following traumatic brain injury (TBI), cerebral metabolic dysfunction, characterized by an elevated cerebral microdialysis (CMD) lactate/pyruvate (LP) ratio, is associated with poor outcome. However, the exact pathophysiological mechanisms underlying this ...

MARY ANN LIEBERT, INC2022

Personalized seizure signature: An interpretable approach to false alarm reduction for long‐term epileptic seizure detection

David Atienza Alonso, Amir Aminifar, Tomas Teijeiro Campo, Dionisije Sopic

Objective Long-term automatic detection of focal seizures remains one of the major challenges in epilepsy due to the unacceptably high number of false alarms from state-of-the-art methods. Our aim was to investigate to what extent a new patient-specific ap ...

2022

Multi-Centroid Hyperdimensional Computing Approach for Epileptic Seizure Detection

David Atienza Alonso, Tomas Teijeiro Campo, Una Pale

Long-term monitoring of patients with epilepsy presents a challenging problem from the engineering perspective of real-time detection and wearable devices design. It requires new solutions that allow continuous unobstructed monitoring and reliable detectio ...

2022

An EEG-based methodology for the estimation of functional brain connectivity networks: Application to the analysis of newborn EEG seizure

Amir Hossein Omidvarnia

This study presents a new methodology for obtaining functional brain networks (FBNs) using multichannel scalp EEG recordings. The developed methodology extracts pair-wise phase synchrony between EEG electrodes to obtain FBNs at delta, theta, and alpha-band ...

ELSEVIER SCI LTD2021

Two-stage Hardware-Friendly Epileptic Seizure Detection Method with a Dynamic Feature Selection

Alexandre Schmid, Keyvan Farhang Razi

A novel low-complexity method of detecting epileptic seizures from intracranial encephalography (iEEG) signals is presented. In the proposed algorithm, coastline, energy and nonlinear energy features of iEEG signals are extracted in a patient-specific two- ...

IEEE2021

Interpreting deep learning models for epileptic seizure detection on EEG signals

David Atienza Alonso, Marina Zapater Sancho, Tomas Teijeiro Campo, Valentin Alexandre Guy Gabeff, Leila Cammoun

While Deep Learning (DL) is often considered the state-of-the art for Artificial Intelligence-based medical decision support, it remains sparsely implemented in clinical practice and poorly trusted by clinicians due to insufficient interpretability of neur ...

2021

Transient Neurovascular Interface for Minimally Invasive Neural Recording and Stimulation

Diego Ghezzi, Philippe Reymond, Laura Ferlauto, Adele Fanelli, Elodie Geneviève Zollinger

Neural interfaces are used to mitigate the burden of traumatic injuries, neurodegenerative diseases, and mental disorders. However, the transient or permanent placement of an interface in close contact with the neural tissue requires invasive surgery, pote ...

Wiley2021

Noninvasive detection of focal seizures in ambulatory patients

David Atienza Alonso, Leila Cammoun

Reliably detecting focal seizures without secondary generalization during daily life activities, chronically, using convenient portable or wearable devices, would offer patients with active epilepsy a number of potential benefits, such as providing more re ...

2020

Monitoring of Cardiovascular and Neurological Diseases Using Wearable Devices

Dionisije Sopic

In this thesis, I focus on monitoring of patients suffering from cardiovascular and neurological diseases through the use of wearable devices. The main diseases considered in this thesis are atrial fibrillation (AF), myocardial infarction (MI), and epileps ...

EPFL2020

Noise-Resilient and Interpretable Epileptic Seizure Detection

David Atienza Alonso, Amir Aminifar, Anthony Hitchcock Thomas

Deep convolutional neural networks have recently emerged as a state-of-the art tool in detection of seizures. Such models offer the ability to extract complex nonlinear representations of an electroencephalogram (EEG) signal which can improve accuracy over ...

IEEE2020

Implantable Autonomous Wireless Closed-loop Bio-electronics for Epilepsy Control

Reza Ranjandish

Implantable electronic medical device (IEMD) is an emerging technology that plays an important role in the treatment of several neurological disorders such as epilepsy, especially in the cases of drug-resistant epilepsy. Recent developments and studies sho ...

EPFL2019

A Self-Learning Methodology for Epileptic Seizure Detection with Minimally Supervised Edge Labeling

David Atienza Alonso, Amir Aminifar, Damián Pascual Ortiz

Epilepsy is one of the most common neurological disorders and affects over 65 million people worldwide. Despite the continuing advances in anti-epileptic treatments, one third of the epilepsy patients live with drug resistant seizures. Besides, the mortali ...

2019

Improvement of Neuroenergetics by Hypertonic Lactate Therapy in Patients with Traumatic Brain Injury Is Dependent on Baseline Cerebral Lactate/Pyruvate Ratio

Pierre Magistretti, Reto Meuli, Luc Pellerin

Energy dysfunction is associated with worse prognosis after traumatic brain injury (TBI). Recent data suggest that hypertonic sodium lactate infusion (HL) improves energy metabolism after TBI. Here, we specifically examined whether the efficacy of HL (3h i ...

Mary Ann Liebert2016

Fingolimod protects against neonatal white matter damage and long-term cognitive deficits caused by hyperoxia

Yohan Van de Looij

Cerebral white matter injury is a leading cause of adverse neurodevelopmental outcome in prematurely born infants involving cognitive deficits in later life. Despite increasing knowledge about the pathophysiology of perinatal brain injury, therapeutic opti ...

Elsevier2016

Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI)

Sean Lewis Hill

BACKGROUND: Current classification of traumatic brain injury (TBI) is suboptimal, and management is based on weak evidence, with little attempt to personalize treatment. A need exists for new precision medicine and stratified management approaches that inc ...

Lippincott, Williams & Wilkins2015