Publications related to Mass spectral interpretation

Adding Color to Mass Spectra of Biopolymers: Charge Determination Analysis (CHARDA) Assigns Charge State to Every Ion Peak

Yury Tsybin, Natalia Gasilova, Laure Menin, Anton Kozhinov, Konstantin Nagornov

Traditionally, mass spectrometry (MS) output is the ion abundance plotted versus the ionic mass-to-charge ratio m/z. While employing only commercially available equipment, Charge Determination Analysis (CHARDA) adds a third dimension to MS, estimating for ...

Amer Chemical Soc2024

Device, system, and method for ion fragmentation by use of an ion mobility device and messenger tagging

Thomas Rizzo, Ahmed Ben Faleh, Stephan Warnke

A device for fragmenting ions by collision induced dissociation, the device intended to be used together with a planar ion mobility apparatus, the device including a first conductive grid having a plurality of first openings, the first conductive grid conf ...

2023

Identification of human milk oligosaccharide positional isomers by combining IMS-CID-IMS and cryogenic IR spectroscopy

Thomas Rizzo, Ahmed Ben Faleh, Stephan Warnke, Ali H Abikhodr, Vasyl Yatsyna

High-resolution ion mobility spectrometry (IMS) coupled with cryogenic infrared spectroscopy has proven to be a powerful technique for the identification of oligosaccharides. However, the need for an extensive database, combined with the scarcity of pure s ...

2023

Electron spectrometer calibration method

Tobias Kippenberg, Fabrizio Carbone, Alexey Sapozhnik, Yujia Yang, Thomas La Grange, Arslan Sajid Raja

The present invention concerns an energy dispersion calibration method for calibrating an electron spectrometer of an electron spectrometer system including at least one electron emission source, electron optics and the electron spectrometer. The method co ...

2023

Predictive modeling of Alfvén eigenmode stability in inductive scenarios in JT-60SA

Javier García Hernández, Matteo Vallar, Antonio José Pereira de Figueiredo

The JT-60SA device offers unique conditions before ITER for the study of the interaction of energetic particles with plasma waves. With similar dimensions to JET, e.g., a major radius but with a slightly more elongated plasma volume, JT-60SA is used as a h ...

Frontiers Media Sa2023

Sheath collapse at critical shallow angle due to kinetic effects

Alessandro Geraldini

The Debye sheath is known to vanish completely in magnetised plasmas for a sufficiently small electron gyroradius and small angle between the magnetic field and the wall. This angle depends on the current onto the wall. When the Debye sheath vanishes, ther ...

IOP Publishing Ltd2022

Gentle nano-electrospray ion source for reliable and efficient generation of microsolvated ions

Oleg Boyarkine, Andrei Zviagin, Vladimir Kopysov

We present herein the design of a nano-electrospray ion source capable of reliable generation of large quantities of microsolvated ions. The source is based on a triple molecular skimmer scheme and can be quickly tuned to generate bare ions or their ionic ...

AIP Publishing2022

Fragment ion-functional group relationships in organic aerosols using aerosol mass spectrometry and mid-infrared spectroscopy

Satoshi Takahama, Amir Yazdani, Imad El Haddad, Nikunj Dudani

Aerosol mass spectrometry (AMS) and mid-infrared spectroscopy (MIR) are two analytical methods for characterizing the chemical composition of OM. While AMS provides high-temporal-resolution bulk measurements, the extensive fragmentation during the electron ...

2022

Coincidence imaging spectroscopy of extreme-ultraviolet photoionisation processes in molecules and clusters

Andrew Daniel Bonnar Clark

Presented here is the design, construction and commissioning of a coincidence imaging spectroscopy endstation coupled to the Harmonium high-harmonic generation (HHG) extreme-ultraviolet photon source at the Lausanne Centre for Ultrafast Science. The endsta ...

EPFL2021

Nonlinear kinetic simulation study of the ion-ion streaming instability in single- and multi-ion species plasmas

Stephan Brunner

The nonlinear evolution of the ion-ion streaming instability (IISI) is studied using numerical techniques novel to this problem that afford direct insight into the evolution of the particle distributions of each species. During the linear phase of the inst ...

2021

Drug-to-Antibody Ratio Estimation via Proteoform Peak Integration in the Analysis of Antibody-Oligonucleotide Conjugates with Orbitrap Fourier Transform Mass Spectrometry

Yury Tsybin, Natalia Gasilova, Laure Menin, Anton Kozhinov, Konstantin Nagornov

The therapeutic efficacy and pharmacokinetics of antibody-drug conjugates (ADCs) in general, and antibody-oligonucleotide conjugates (AOCs) in particular, depend on the drug-to-antibody ratio (DAR) distribution and average value. The DAR is considered a cr ...

AMER CHEMICAL SOC2021

Numerics and computation in gyrokinetic simulations of electromagnetic turbulence with global particle-in-cell codes

Laurent Villard, Alberto Bottino, Emmanuel Lanti

Electromagnetic turbulence is addressed in tokamak and stellarator plasmas with the global gyrokinetic particle-in-cell codes ORB5 (E Lanti et al, Comp. Phys. Comm., 251, 107072 (2020)) and EUTERPE (V Kornilov et al, Phys. Plasmas, 11, 3196 (2004)). The la ...

2021

Nighttime chemistry of biomass burning emissions in urban areas: A dual mobile chamber study

Athanasios Nenes, Spyros Pandis

Residential biomass burning for heating purposes is an important source of air pollutants during winter. Here we test the hypothesis that significant secondary organic aerosol production can take place even during winter nights through oxidation of the emi ...

Copernicus GmbH2021

Toward High-Throughput Cryogenic IR Fingerprinting of Mobility-Separated Glycan Isomers

Thomas Rizzo, Ahmed Ben Faleh, Stephan Warnke

Infrared (IR) spectroscopy is a powerful tool used to infer detailed structural information on molecules, often in conjunction with quantum-chemical calculations. When applied to cryogenically cooled ions, IR spectra provide unique fingerprints that can be ...

2021

Time-resolved formation of excited atomic and molecular states in XUV-induced nanoplasmas in ammonia clusters

Marcel Drabbels, Andrew Daniel Bonnar Clark, Verónica Oliver Álvarez de Lara

High intensity XUV radiation from a free-electron laser (FEL) was used to create a nanoplasma inside ammonia clusters with the intent of studying the resulting electron-ion interactions and their interplay with plasma evolution. In a plasma-like state, ele ...

ROYAL SOC CHEMISTRY2020

Bootstrapping massive quantum field theories

Denis Karateev, João Miguel Augusto Penedones Fernandes

We propose a new non-perturbative method for studying UV complete unitary quantum field theories (QFTs) with a mass gap in general number of spacetime dimensions. The method relies on unitarity formulated as positive semi-definiteness of the matrix of inne ...

Springer Nature2020

First Observation of Excited Omega(-)(b) States

Olivier Schneider, Aurelio Bay, Yiming Li, Guido Haefeli, Frédéric Blanc, Christoph Frei, Tatsuya Nakada, Michel De Cian, Luca Pescatore, Elena Graverini, Veronica Sølund Kirsebom, François Fleuret, Matthieu Philippe Luther Marinangeli, Minh Tâm Tran, Chitsanu Khurewathanakul, Pietro Marino, Federico Leo Redi, Renato Quagliani, Plamen Hristov Hopchev, Federico Betti, Maxime Schubiger, Guido Andreassi, Aravindhan Venkateswaran, Violaine Bellée, Luis Miguel Garcia Martin, Maria Vieites Diaz, Vitalii Lisovskyi, Olivier Göran Girard, Axel Kuonen, Jian Wang, Mingkui Wang, Preema Rennee Pais, Zhirui Xu, Pavol Stefko, Yi Zhang, Tara Nanut, Maria Elena Stramaglia, Lei Zhang, Vladimir Macko, Jessica Prisciandaro, Guillaume Max Pietrzyk, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

Observation of a new baryon state in the Lambda(0)(b)pi(+)pi(-) mass spectrum

Olivier Schneider, Aurelio Bay, Yiming Li, Guido Haefeli, Frédéric Blanc, Christoph Frei, Tatsuya Nakada, Michel De Cian, Luca Pescatore, Elena Graverini, Chitsanu Khurewathanakul, François Fleuret, Veronica Sølund Kirsebom, Matthieu Philippe Luther Marinangeli, Minh Tâm Tran, Pietro Marino, Renato Quagliani, Federico Leo Redi, Federico Betti, Plamen Hristov Hopchev, Maxime Schubiger, Aravindhan Venkateswaran, Guido Andreassi, Luis Miguel Garcia Martin, Violaine Bellée, Vitalii Lisovskyi, Olivier Göran Girard, Axel Kuonen, Jian Wang, Mingkui Wang, Preema Rennee Pais, Zhirui Xu, Pavol Stefko, Yi Zhang, Tara Nanut, Maria Elena Stramaglia, Lei Zhang, Vladimir Macko, Jessica Prisciandaro, Guillaume Max Pietrzyk, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

Observation of New Xi(0)(c) Baryons Decaying to Lambda K-+(c)-

Lesya Shchutska, Olivier Schneider, Aurelio Bay, Yiming Li, Guido Haefeli, Frédéric Blanc, Christoph Frei, Tatsuya Nakada, Michel De Cian, Elena Graverini, Veronica Sølund Kirsebom, François Fleuret, Matthieu Philippe Luther Marinangeli, Minh Tâm Tran, Pietro Marino, Renato Quagliani, Federico Leo Redi, Federico Betti, Plamen Hristov Hopchev, Violaine Bellée, Aravindhan Venkateswaran, Maria Vieites Diaz, Vitalii Lisovskyi, Preema Rennee Pais, Pavol Stefko, Elisabeth Maria Niel, Tara Nanut, Jian Wang, Maria Elena Stramaglia, Mingkui Wang, Vladimir Macko, Guillaume Max Pietrzyk, Zhirui Xu, Yi Zhang, Sebastian Schulte, Lino Ferreira Lopes, Lei Zhang, Surapat Ek-In, Ho Ling Li, Carina Trippl, Mark Tobin, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

Nonlinear Gyrokinetic Coulomb Collision Operator

Paolo Ricci, Rogério Manuel Cabete De Jesus Jorge, Baptiste Jimmy Frei

A gyrokinetic Coulomb collision operator is derived, which is particularly useful to describe the plasma dynamics at the periphery region of magnetic confinement fusion devices. The derived operator is able to describe collisions occurring in distribution ...

Cambridge University Press2019