Pulmonary fibrosis

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Related publications (30)

Optimized Steerable Wavelets for Texture Analysis of Lung Tissue In 3-D CT: Classification of Usual Interstitial Pneumonia

Michaël Unser, Adrien Raphaël Depeursinge, Pedram Pad

Our aim is to optimize wavelet-based feature extraction for differentiating between the classical versus atypical pattern of usual interstitial pneumonia (UIP) in volumetric CT. Our proposal is to act on the bandwidth of steerable wavelets while maintainin ...

IEEE2015

Development of Implantable Electrodes Based on Polymer Derived Ceramics

Jonas Grossenbacher

The invention of heart pacemakers in the 50's aims to help patients to overcome heart strokes, which represent the first cause of death worldwide. In Europe and in the USA, more than 3000 pacemakers are implanted every day. Despite the constant evolution o ...

EPFL2015

Thymic stromal lymphopoietin plays divergent roles in murine models of atopic and nonatopic airway inflammation

Nicola Harris, Benjamin John Marsland, Ilaria Mosconi

BackgroundThymic stromal lymphopoietin (TSLP) is a cytokine primarily produced by epithelial cells, which has been shown to be a potent inducer of T-helper 2 (Th2)-type responses. However, TSLP has pleiotropic effects upon immune cells, and although extens ...

Wiley-Blackwell2014

Expression of the leptin receptor outside of bone marrow-derived cells regulates tuberculosis control and lung macrophage MHC expression

John McKinney

Leptin is a pleiotropic hormone proposed to link nutritional status to the development of strong Th1 immunity. Because Mycobacterium tuberculosis control is affected by starvation and diabetes, we studied the role of the leptin receptor in regulating disti ...

American Association of Immunologists ; Oxford University Press2011

RC time constant of single lung equals that of both lungs together: a study in chronic thromboembolic pulmonary hypertension

Nikolaos Stergiopoulos, Nico Westerhof

The product of resistance, R, and compliance, C (RC time), of the entire pulmonary circulation is constant. It is unknown if this constancy holds for individual lungs. We determined R and C in individual lungs in chronic thromboembolic pulmonary hypertensi ...

2009

Lung Tissue Classification Using Wavelet Frames

Michaël Unser, Daniel Sage, Adrien Raphaël Depeursinge

We describe a texture classification system that identifies lung tissue patterns from high-resolution computed tomography (HRCT) images of patients affected with interstitial lung diseases (ILD). This pattern recognition task is part of an image-based diag ...

IEEE2007

Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix

Jean-Jacques Meister, Boris Hinz, Pierre Jean Arnould Wipff

The conjunctive presence of mechanical stress and active transforming growth factor beta1 (TGF-beta1) is essential to convert fibroblasts into contractile myofibroblasts, which cause tissue contractures in fibrotic diseases. Using cultured myofibroblasts a ...

Rockefeller University Press2007

The myofibroblast: one function, multiple origins

Boris Hinz

The crucial role played by the myofibroblast in wound healing and pathological organ remodeling is well established; the general mechanisms of extracellular matrix synthesis and of tension production by this cell have been amply clarified. This review disc ...

American Society for Investigative Pathology2007

Extracellular Matrix Remodeling by Dynamic Strain in a 3D Tissue Engineered Human Airway Wall Model

Melody Swartz

Airway wall remodeling is a hallmark of asthma, characterized by subepithelial thickening and extracellular matrix (ECM) remodeling. Mechanical stress due to hyperresponsive smooth muscle cells may contribute to this remodeling, but its extent and relevanc ...

2006

Sniff nasal pressure: a sensitive respiratory test to assess progression of amyotrophic lateral sclerosis

Patrick Aebischer

Impairment of pulmonary function is a major prognostic indicator in amyotrophic lateral sclerosis (ALS). Forced vital capacity (FVC) and maximal voluntary ventilation (MVV) decline linearly and are commonly used to assess disease progression. The aim of th ...

1999

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