People for the Ethical Treatment of AnimalsPeople for the Ethical Treatment of Animals (PETA; ˈpiːtə) is an American animal rights nonprofit organization based in Norfolk, Virginia, and led by Ingrid Newkirk, its international president. PETA reports that PETA entities have more than 9 million members globally. Founded in March 1980 by Newkirk and animal rights activist Alex Pacheco, the organization first caught the public's attention in the summer of 1981 during what became known as the Silver Spring monkeys case.
Animal rightsAnimal rights is the philosophy according to which many or all sentient animals have moral worth independent of their utility to humans, and that their most basic interests—such as avoiding suffering—should be afforded the same consideration as similar interests of human beings. Broadly speaking, and particularly in popular discourse, the term "animal rights" is often used synonymously with "animal protection" or "animal liberation".
ToxicologyToxicology is a scientific discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosing and treating exposures to toxins and toxicants. The relationship between dose and its effects on the exposed organism is of high significance in toxicology. Factors that influence chemical toxicity include the dosage, duration of exposure (whether it is acute or chronic), route of exposure, species, age, sex, and environment.
In vivoStudies that are in vivo (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism. This is not to be confused with experiments done in vitro ("within the glass"), i.e., in a laboratory environment using test tubes, Petri dishes, etc.
VivisectionVivisection () is surgery conducted for experimental purposes on a living organism, typically animals with a central nervous system, to view living internal structure. The word is, more broadly, used as a pejorative catch-all term for experimentation on live animals but the term is rarely used by practising scientists. Human vivisection, such as live organ procurement, has been perpetrated as a form of torture.
ZebrafishThe zebrafish (Danio rerio) is a freshwater fish belonging to the minnow family (Cyprinidae) of the order Cypriniformes. Native to India and South Asia, it is a popular aquarium fish, frequently sold under the trade name zebra danio (and thus often called a "tropical fish" although both tropical and subtropical). It is also found in private ponds. The zebrafish is an important and widely used vertebrate model organism in scientific research, for example in drug development, in particular pre-clinical development.
Medical researchMedical research (or biomedical research), also known as experimental medicine, encompasses a wide array of research, extending from "basic research" (also called bench science or bench research), – involving fundamental scientific principles that may apply to a preclinical understanding – to clinical research, which involves studies of people who may be subjects in clinical trials. Within this spectrum is applied research, or translational research, conducted to expand knowledge in the field of medicine.
Cruelty to animalsCruelty to animals, also called animal abuse, animal neglect or animal cruelty, is the infliction by omission (neglect) or by commission by humans of suffering or harm upon non-human animals. More narrowly, it can be the causing of harm or suffering for specific achievements, such as killing animals for entertainment; cruelty to animals sometimes encompasses inflicting harm or suffering as an end in itself, referred to as zoosadism. Divergent approaches to laws concerning animal cruelty occur in different jurisdictions throughout the world.
African clawed frogThe African clawed frog (Xenopus laevis), also known as simply Xenopus, African clawed toad, African claw-toed frog or the Platanna) is a species of African aquatic frog of the family Pipidae. Its name is derived from the short black claws on its feet. The word Xenopus means 'strange foot' and laevis means 'smooth'. The species is found throughout much of Sub-Saharan Africa (Nigeria and Sudan to South Africa), and in isolated, introduced populations in North America, South America, Europe, and Asia.
Model organismA model organism (often shortened to model) is a non-human species that is extensively studied to understand particular biological phenomena, with the expectation that discoveries made in the model organism will provide insight into the workings of other organisms. Model organisms are widely used to research human disease when human experimentation would be unfeasible or unethical. This strategy is made possible by the common descent of all living organisms, and the conservation of metabolic and developmental pathways and genetic material over the course of evolution.
Animal disease modelAn animal model (short for animal disease model) is a living, non-human, often genetic-engineered animal used during the research and investigation of human disease, for the purpose of better understanding the disease process without the risk of harming a human. Although biological activity in an animal model does not ensure an effect in humans, many drugs, treatments and cures for human diseases are developed in part with the guidance of animal models.
Animal welfareAnimal welfare is the well-being of non-human animals. Formal standards of animal welfare vary between contexts, but are debated mostly by animal welfare groups, legislators, and academics. Animal welfare science uses measures such as longevity, disease, immunosuppression, behavior, physiology, and reproduction, although there is debate about which of these best indicate animal welfare. Respect for animal welfare is often based on the belief that nonhuman animals are sentient and that consideration should be given to their well-being or suffering, especially when they are under the care of humans.
VeterinarianA veterinarian (vet) is a medical professional who practices veterinary medicine. They manage a wide range of health conditions and injuries in non-human animals. Along with this, veterinarians also play a role in animal reproduction, health management, conservation, husbandry and breeding and preventive medicine like nutrition, vaccination and parasitic control as well as biosecurity and zoonotic disease surveillance and prevention.
AlbinismAlbinism is the congenital absence of melanin in an animal or plant resulting in white hair, feathers, scales and skin and reddish pink or blue eyes. Individuals with the condition are referred to as albinos. Varied use and interpretation of the terms mean that written reports of albinistic animals can be difficult to verify. Albinism can reduce the survivability of an animal; for example, it has been suggested that albino alligators have an average survival span of only 24 hours due to the lack of protection from UV radiation and their lack of camouflage to avoid predators.
Animal Liberation FrontThe Animal Liberation Front (ALF) is an international, leaderless, decentralized political and social resistance movement that advocates and engages in what it calls non-violent direct action in protest against incidents of animal cruelty. It originated in the 1970s from the Bands of Mercy. Participants state it is a modern-day Underground Railroad, removing animals from laboratories and farms, destroying facilities, arranging safe houses, veterinary care and operating sanctuaries where the animals subsequently live.
Pharmaceutical industryThe pharmaceutical industry discovers, develops, produces, and markets pharmaceutical drugs for the use as medications to be administered to patients (or self-administered), with the aim to cure and prevent diseases, or alleviate symptoms. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy using drug testing and marketing of drugs. The global pharmaceuticals market produced treatments worth $1,228.
Drug discoveryIn the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered by identifying the active ingredient from traditional remedies or by serendipitous discovery, as with penicillin. More recently, chemical libraries of synthetic small molecules, natural products or extracts were screened in intact cells or whole organisms to identify substances that had a desirable therapeutic effect in a process known as classical pharmacology.
Animal euthanasiaAnimal euthanasia (euthanasia from εὐθανασία; "good death") is the act of killing an animal humanely, most commonly with injectable drugs. Reasons for euthanasia include incurable (and especially painful) conditions or diseases, lack of resources to continue supporting the animal, or laboratory test procedures. Euthanasia methods are designed to cause minimal pain and distress. Euthanasia is distinct from animal slaughter and pest control. In domesticated animals, this process is commonly referred to by euphemisms such as "put down" or "put to sleep".
In vitroIn vitro (meaning in glass, or in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology and its subdisciplines are traditionally done in labware such as test tubes, flasks, Petri dishes, and microtiter plates.
Guinea pigThe guinea pig or domestic guinea pig (Cavia porcellus), also known as the cavy or domestic cavy ('keɪvi ), is a species of rodent belonging to the genus Cavia in the family Caviidae. Breeders tend to use the word cavy to describe the animal, while in scientific and laboratory contexts, it is far more commonly referred to by the common name guinea pig. Despite their common name, guinea pigs are not native to Guinea, nor are they closely related biologically to pigs, and the origin of the name is still unclear.
