Publications related to Tunneling nanotube

Unraveling mitochondrial dynamics: exploring asymmetries and function through advanced microscopy

Still displaying characteristics of their bacterial origin, such as autonomous division, motility, and their own genome, mitochondria remain an elusive component of modern eukaryotes. They produce most of the cell's energy in the form of adenosine triphosp ...

EPFL2024

Stimulus-responsive assembly of nonviral nucleocapsids

Angela Steinauer

Controlled assembly of a protein shell around a viral genome is a key step in the life cycle of many viruses. Here we report a strategy for regulating the co-assembly of nonviral proteins and nucleic acids into highly ordered nucleocapsids in vitro. By fus ...

Nature Portfolio2024

Aeroelastic characterisation of a bio-inspired flapping membrane wing

Karen Ann J Mulleners, Alexander Gehrke, Esra Uksul, Jules Ange Philippe Richeux

Natural fliers like bats exploit the complex fluid-structure interaction between their flexible membrane wings and the air with great ease. Yet, replicating and scaling the balance between the structural and fluid-dynamical parameters of unsteady membrane ...

IOP Publishing Ltd2022

Mammalian membrane trafficking as seen through the lens of bacterial toxins

Françoise Gisou van der Goot Grunberg, Francisco De Magalhães Sarmento R De Mesquita, Oksana Andrei Sergeeva

A fundamental question of eukaryotic cell biology is how membrane organelles are organised and interact with each other. Cell biologists address these questions by characterising the structural features of membrane compartments and the mechanisms that coor ...

WILEY2020

Metabolic implications of organelle-mitochondria communication

Carlos Canto Alvarez

Cellular organelles are not static but show dynamism-a property that is likely relevant for their function. In addition, they interact with other organelles in a highly dynamic manner. In this review, we analyze the proteins involved in the interaction bet ...

WILEY2019

Miniaturized single-cell analyses for biomedical applications

Loïc Arvind Roger Arm

Numerous diseases affecting living beings have as a cause a modification of gene expression resulting in anomalous expression of proteins in up- or down-regulated fashion, with altered functions or expression of proteins that are not present in the cell in ...

EPFL2017

Connecting vesicular transport with lipid synthesis: FAPP2

Giovanni D'Angelo

Next to the protein-based machineries composed of small G-proteins, coat complexes, SNAREs and tethering factors, the lipid-based machineries are emerging as important players in membrane trafficking. As a component of these machineries, lipid transfer pro ...

2012

Mitochondrial Dysfunction in Genetic Animal Models of Parkinson's Disease

Elpida Tsika, Darren Moore, Alzbeta Trancikova

Mitochondria are highly dynamic, multifunctional organelles. Aside from their major role in energy metabolism, they are also crucial for many cellular processes including neurotransmission, synaptic maintenance, calcium homeostasis, cell death, and neurona ...

2012

Pore-forming toxins induce multiple cellular responses promoting survival

Françoise Gisou van der Goot Grunberg, Mirko Bischofberger, Rodrigo Manuel Gonzalez, Sylvia Ho

Pore-forming toxins (PFTs) are secreted proteins that contribute to the virulence of a great variety of bacterial pathogens. They inflict one of the more disastrous damages a target cell can be exposed to: disruption of plasma membrane integrity. Since thi ...

Wiley-Blackwell2011

Membrane nanotubes drawn by optical tweezers transmit electrical signals between mammalian cells over long distances

Horst Vogel, Marinela Gjoni Boillat, Pedro Pascoal, Davor Kosanic

Biological cells continuously change shape allowing essential functions such as cell motility, vesicle-mediated release/uptake of soluble and membrane components or nanotube-mediated cell–cell communications. Here we use single cell micromanipulation to in ...

Royal Society of Chemistry2010

Carbon nanotubes might improve neuronal performance by favouring electrical shortcuts

Henry Markram, Michele Giugliano, Luca Gambazzi

Carbon nanotubes have been applied in several areas of nerve tissue engineering to probe and augment cell behaviour, to label and track subcellular components, and to study the growth and organization of neural networks. Recent reports show that nanotubes ...

Nature Publishing Group2009