Publications related to Clinical officer

Resource-Efficient Continual Learning for Personalized Online Seizure Detection

David Atienza Alonso, Giovanni Ansaloni, José Angel Miranda Calero, Jonathan Dan, Amirhossein Shahbazinia, Flavio Ponzina

Epilepsy, a major neurological disease, requires careful diagnosis and treatment. However, the detection of epileptic seizures remains a significant challenge. Current clinical practice relies on expert analysis of EEG signals, a process that is time-consu ...

IEEE2024

Development and clinical validation of computational imaging biomarkers for neurodegenerative diseases

Veronica Lily Ravano

Neurodegenerative and neuroinflammatory disorders often involve complex pathophysiological mechanisms that are â to this date â only partially understood. A more comprehensive understanding of those microstructural processes and their characterization ...

EPFL2024

Machine learning and its impact on psychiatric nosology: Findings from a qualitative study among German and Swiss experts

The increasing integration of Machine Learning (ML) techniques into clinical care, driven in particular by Deep Learning (DL) using Artificial Neural Nets (ANNs), promises to reshape medical practice on various levels and across multiple medical fields. Mu ...

2023

Cortical lesions, central vein sign, and paramagnetic rim lesions in multiple sclerosis: Emerging machine learning techniques and future avenues

Jean-Philippe Thiran, Meritxell Bach Cuadra, Tobias Kober, Francesco La Rosa, Cristina Granziera, Maxence Charles F Wynen

The current diagnostic criteria for multiple sclerosis (MS) lack specificity, and this may lead to misdiagnosis, which remains an issue in present-day clinical practice. In addition, conventional biomarkers only moderately correlate with MS disease progres ...

ELSEVIER SCI LTD2022

Re-focusing explainability in medicine

Using artificial intelligence to improve patient care is a cutting-edge methodology, but its implementation in clinical routine has been limited due to significant concerns about understanding its behavior. One major barrier is the explainability dilemma a ...

2022

Toward an objective assessment of mobility in clinical and daily activity settings

Arash Atrsaei

Quantification of mobility is the key to monitor the progression of mobility disorders as well as the effect of an intervention. Inertial measurement units (IMUs) with dedicated algorithms can quantify postural transitions and gait as the two key aspects o ...

EPFL2021

GA4GH: International policies and standards for data sharing across genomic research and healthcare

Jean-Pierre Hubaux, Jamal Nasir, Junjun Zhang

The Global Alliance for Genomics and Health (GA4GH) aims to accelerate biomedical advances by enabling the responsible sharing of clinical and genomic data through both harmonized data aggregation and federated approaches. The decreasing cost of genomic se ...

Elsevier2021

Clinical Neuroimaging Using 7 T MRI: Challenges and Prospects

Rolf Gruetter, Lijing Xin, Özlem Ipek, Pascal Martelli, François Lazeyras

The aim of this article is to illustrate the principal challenges, from the medical and technical point of view, associated with the use of ultrahigh field (UHF) scanners in the clinical setting and to present available solutions to circumvent these limita ...

2018

Multispectral Near-Infrared Optical Tomography for Cancer Hypoxia Study in Mice

Scott Anthony Lindner, Matthias Wolf, Jingjing Jiang, Markus Rudin

Oxygenation of a tumor is one of the most important predictive factors: hypoxia is associated with aggressive tumors and substantially lower survival rate. Despite this high relevance of tumor oxygenation, there is currently no bedside technique available ...

SPRINGER INTERNATIONAL PUBLISHING AG2018

Development of a Database for Translational Spinal Cord Injury Research

Grégoire Courtine

Efforts to understand spinal cord injury (SCI) and other complex neurotrauma disorders at the pre-clinical level have shown progress in recent years. However, successful translation of basic research into clinical practice has been slow, partly because of ...

Mary Ann Liebert2014

Immunoisolated xenogenic chromaffin cell therapy for chronic pain. Initial clinical experience

Patrick Aebischer, Julien Favre

BACKGROUND: Chromaffin cells from the adrenal gland secrete a mixture of compounds that have a strong analgesic effect, especially when administered intrathecally. Many studies in animal models have shown that discordant xenogeneic cell isolates, including ...

1996