Publications related to Balance disorder

Out-of-body illusion induced by visual-vestibular stimulation

Olaf Blanke, Bruno Herbelin, Hsin-Ping Wu, Sophie Jacqueline Andrée Betka, Florian Lance, Estelle Nakul

Out-of-body experiences (OBEs) are characterized by the subjective feeling of being located outside one's physical body and perceiving one's own body from an elevated perspective looking downwards. OBEs have been correlated with abnormal integration of bod ...

Cell Press2023

Microgravity induces overconfidence in perceptual decision-making

Leyla Loued-Khenissi, Davide Scaramuzza, Christian Pfeiffer

Does gravity affect decision-making? This question comes into sharp focus as plans for interplanetary human space missions solidify. In the framework of Bayesian brain theories, gravity encapsulates a strong prior, anchoring agents to a reference frame via ...

Nature Portfolio2023

Simulating the progression of brain structural alterations in Parkinson's disease

Chang-Hyun Park

Considering brain structural alterations as neurodegenerative consequences of Parkinson's disease (PD), we sought to infer the progression of PD via the ordering of brain structural alterations from cross-sectional MRI observations. Having measured cortica ...

NATURE PORTFOLIO2022

Variants in USP48 encoding ubiquitin hydrolase are associated with autosomal dominant non-syndromic hereditary hearing loss

Nicolas Jean Philippe Guex

Non-Syndromic Hereditary Hearing Loss (NSHHL) is a genetically heterogeneous sensory disorder with about 120 genes already associated. Through exome sequencing (ES) and data aggregation, we identified a family with six affected individuals and one unrelate ...

Oxford University Press2021

Repeat stereotactic radiosurgery for progressive vestibular schwannomas after previous radiosurgery: a systematic review and meta-analysis

Constantin Tuleasca, Adrien Jean Régis Maurice Hilaire

Vestibular schwannomas (VS) are slow-growing intracranial extraaxial benign tumors, developing from the vestibular part of the eight cranial nerves. Stereotactic radiosurgery (SRS) has now a long-term scientific track record as first intention treatment fo ...

SPRINGER2021

Exploring the Contribution of Proprioceptive Reflexes to Balance Control in Perturbed Standing

Auke Ijspeert, Anne Daniëlle Koelewijn

Humans control balance using different feedback loops involving the vestibular system, the visual system, and proprioception. In this article, we focus on proprioception and explore the contribution of reflexes based on force and length feedback to standin ...

FRONTIERS MEDIA SA2020

Postural Control and Consciousness and Their Applications to Lower-Limb Exoskeletons

Jemina Fasola

Human postural control requires high coordination and is distributed over the whole musculoskeletal and nervous systems. Hence, postural balance can be impaired due to various pathologies. Efficient rehabilitation programs and technological solutions are t ...

EPFL2020

One the effect of the Vertical Axis Alignment on Cybersickness and Game Experience in Supine Posture

Ronan Boulic, Nana Tian, Louis Philippe Simoes Lopes

Cybersickness is still an inevitable adverse effect when using VR systems, resulting in different levels of discomfort, and potentially breaking the immersive experience. To date, few studies have focused on exploring VR experience in the supine posture. R ...

IEEE2020

Flight of mind: Sensorimotor and multisensory embodiment with aviation robotics, flight simulator, and virtual reality

Myeong Seop Song

Normally, humans experience an 'I' as residing in one's body and as the agent of one's actions. In other words, the self is experienced as being inside the body (self-location), as having a body (self-identification), and as being able to control the perso ...

EPFL2020

Efficient viral transduction in mouse inner ear hair cells with utricle injection and AAV9-PHP.B

Bernard Schneider, Paola Andrea Solanes Vega

Viral delivery of exogenous coding sequences into the inner ear has the potential for therapeutic benefit for patients suffering genetic or acquired hearing loss. To devise improved strategies for viral delivery, we investigated two injection techniques, r ...

2020

Error Augmentation Improves Visuomotor Adaptation during a Full-Body Balance Task

Olaf Blanke, Hannes Bleuler, Mohamed Bouri, Oliver Alan Kannape, Jemina Fasola

Visual amplification of kinematic errors has successfully been applied to improve performance for upper limb movements. In this study, we investigated whether visual error augmentation can promote faster adaptation during a full-body balance task. Healthy ...

IEEE2019

Effects of repeated waist-pull perturbations on gait stability in subjects with cerebellar ataxia

Silvestro Micera

Background: Damage to the cerebellum can affect neural structures involved in locomotion, causing gait and balance disorders. However, the integrity of cerebellum does not seem to be critical in managing sudden and unexpected environmental changes such as ...

BioMed Central2019

Non-invasive, Brain-controlled Functional Electrical Stimulation for Locomotion Rehabilitation in Individuals with Paraplegia

Mohamed Bouri, Solaiman Shokur, Miguel Nicolelis

Spinal cord injury (SCI) impairs the flow of sensory and motor signals between the brain and the areas of the body located below the lesion level. Here, we describe a neurorehabilitation setup combining several approaches that were shown to have a positive ...

Nature Research2019

An Event-Driven Closed-Loop System for Real-Time FES Control

Silvestro Micera, Andrea Crema, Danilo Demarchi

Active functional rehabilitation procedures, exoskeleton application and prosthesis employment are essential tools for the society life reinstatement of subjects affected by neuromuscular disorders or victims of serious physical accident. In this paper we ...

IEEE2019

Modulation of vection latencies in the full-body illusion

Olaf Blanke, Bruno Herbelin, Alessandro Nesti, Giulio Rognini

Current neuroscientific models of bodily self-consciousness (BSC) argue that inaccurate integration of sensory signals leads to altered states of BSC. Indeed, using virtual reality technology, observers viewing a fake or virtual body while being exposed to ...

2018

Preliminary Study: Effects of Visual Distortion on Standing Balance Motion Amplitude and Visual Dependency on an Unstable Surface

Olaf Blanke, Hannes Bleuler, Mohamed Bouri, Jemina Fasola

Visual feedback is a common method to enhance motor learning and is widely used in rehabilitation institutes. Although balance training with visual feedback has shown positive results, the most effective way to provide the feedback is still open to researc ...

2018

Pretherapeutic resting-state fMRI profiles are associated with MR signature volumes after stereotactic radiosurgical thalamotomy for essential tremor

Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, Meritxell Bach Cuadra, Thomas William Arthur Bolton, Constantin Tuleasca, Adrien Jean Régis Maurice Hilaire, Elena Najdenovska

OBJECTIVE Essential tremor (ET) is the most common movement disorder. Drug-resistant ET can benefit from standard stereotactic deep brain stimulation or radiofrequency thalamotomy or, alternatively, minimally invasive techniques, including stereotactic rad ...

AMER ASSOC NEUROLOGICAL SURGEONS2018

Differential effects of vestibular processing on orienting exogenous and endogenous covert visual attention

Olaf Blanke, Mariia Kaliuzhna, Andrea Serino, Steve Michel Berger

Recent research highlights the overwhelming role of vestibular information for higher order cognition. Central to body perception, vestibular cues provide information about self-location in space, self-motion versus object motion, and modulate the percepti ...

2019

Bodily self-consciousness and its disorders, The Parietal Lobe

Olaf Blanke, Roberta Ronchi, Hyeongdong Park

Research in clinical and human neuroscience indicates that important brain mechanisms of self-consciousness are based on the integration of multisensory bodily signals (i.e., bodily self-consciousness: BSC), including signals coming from outside our body ( ...

2018

Multisensory interactions in peripersonal space and their contributions to bodily self-consciousness

Petr Grivaz

What is the relevance of the body and body-transformed sensory information for subjective experience? In the last two decades, paradigms from cognitive neuroscience have demonstrated that the subjective sensations of possessing a body (body ownership, BO), ...

EPFL2017