Rolf GruetterAwards:
1999 Young Investigator Award Plenary Lectureship
, International Society for Neurochemistry
2011 Fellow
, ESMRMB
2011 Teaching Award
, Section Sciences de la Vie, EPFL
Jean-Philippe ThiranJean-Philippe Thiran was born in Namur, Belgium, in August 1970. He received the Electrical Engineering degree and the PhD degree from the Université catholique de Louvain (UCL), Louvain-la-Neuve, Belgium, in 1993 and 1997, respectively. From 1993 to 1997, he was the co-ordinator of the medical image analysis group of the Communications and Remote Sensing Laboratory at UCL, mainly working on medical image analysis. Dr Jean-Philippe Thiran joined the Signal Processing Institute (ITS) of the Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland, in February 1998 as a senior lecturer. He was promoted to Assistant Professor in 2004, to Associate Professor in 2011 and is now a Full Professor since 2020. He also holds a 20% position at the Department of Radiology of the University of Lausanne (UNIL) and of the Lausanne University Hospital (CHUV) as Associate Professor ad personam. Dr Thiran's current scientific interests include
Computational medical imaging: acquisition, reconstruction and analysis of imaging data, with emphasis on regularized linear inverse problems (compressed sensing, convex optimization). Applications to medical imaging: diffusion MRI, ultrasound imaging, inverse planning in radiotherapy, etc.Computer vision & machine learning: image and video analysis, with application to facial expression recognition, eye tracking, lip reading, industrial inspection, medical image analysis, etc.
Lothar HelmLothar Helm was born in Gernsbach (Germany) in 1952. He studied physics at the University of Karlsruhe (Germany) and obtained his diploma degree in 1977. He remained in Karlsruhe for his Ph.D. research with Prof. H. G. Hertz and received his degree in physical chemistry in 1980. In 1980 he joined the laboratories of Prof. André Merbach at the University of Lausanne, Switzerland. From 1983 to 2001 he was maître denseignement et de recherche at the Faculty of Science of the University of Lausanne. In 2001 he moved, together with the whole chemistry department, from the University of Lausanne to the Ecole Polytechnique Fédérale de Lausanne (EPFL). Since 2006 he is adjunct professor at the Institute of Chemical Sciences and Engineering at EPFL and director of the NMR services of the institute.
From 2007 to 2011 he was director of the "Conférence du corps Enseignant" at EPFL. Since 2011 he is member of the School Assembly of EPFL (AE).
MAIN RESEARCH INTERESTS:
Physico-chemical studies of contrast agents for medical magnetic resonance imaging (MRI)
Study of reactivity and reaction mechanisms in coordination chemistry by variable temperature and pressure nuclear magnetic resonance
Computer simulation of solvent dynamics on cations and metal complexes in solution
Professional course
Cristina Ramona CudalbuCristina Cudalbu obtained her Bachelors of Science degree in Medical Physics in 2002 and Masters of Science degree in Biophysics and Medical Physics in 2003, both from University Babes-Bolyai, Cluj-Napoca, Romania. In 2006 she obtained her PhD degree in Localized Proton MRS and time domain quantification of cerebral metabolites at 7T and 4.7T at University Lyon 1, RMN Laboratory, Villeurbanne, France.In 2007, she joined, as a Scientist, the Laboratory for Functional and Metabolic Imaging at EPFL, where she implemented new acquisition and quantification techniques for in vivo nitrogen, proton and carbon MRS for preclinical studies. Starting 2012, Cristina Cudalbu was appointed as Research Staff Scientist and 9.4T MRI Operational Manager at Centre d’Imagerie Biomédicale (CIBM) at EPFL. She is now developing new research lines at CIBM, being oriented towards new acquisition and quantification techniques for in vivo proton, phosphorous, carbon, nitrogen MRS and fast MRSI, diffusion weighted spectroscopy and brain macromolecules quantification. She is now applying these developments on chronic hepatic encephalopathy, a research area that she developed at CIBM (https://actu.epfl.ch/news/when-liver-disease-affects-the-brain/), and on different collaborative projects with researchers from the five partner institutions of CIBM. Lijing XinLijing Xin is a research staff scientist and 7T MR Operational Manager at the Center for Biomedical Imaging (CIBM), Ecole polytechnique fédérale de Lausanne (EPFL), Switzerland. Her research interests focus on developing cutting-edge magnetic resonance spectroscopy and imaging methods for better understanding the brain function and the pathophysiology of neurological diseases. Her journey on magnetic resonance imaging (MRI) started from her master project during 2002-2005, where she developed a gradient unit with eddy current compensation and a pulse sequence generator for MRI spectrometer, which enhanced her knowledge in MR instrumentation. Later, she obtained her PhD in physics from Ecole polytechnique fédérale de Lausanne (EPFL) in 2010, where she focused on developing various novel 1H and 13C magnetic resonance spectroscopy (MRS) acquisition and quantification methods as well as RF coils on high field preclinical MR scanners. Afterwards, she started working on the clinical MR platforms including both 3 and 7T and continued to improve and develop novel acquisition and quantification methods for 1H, 13C and 31P nuclei. She carries on interdisciplinary collaborations with different partners, particularly with clinical partners where translational strategies are performed to explore the pathophysiology of psychiatric disorders and disease biomarkers for early diagnose and intervention.
Henrik Moodysson RønnowHenrik Ronnow was born in Copenhagen in 1974. He was awarded his master's degree in physics in 1996. Having earned his doctorate in 2000, he left Denmark for training at the Laue-Langevin Institute in Grenoble. Between 2000 and 2002, he held a Marie Curie Fellowship hosted by the Atomic Energy Commission. In 2002 he was appointed as an invited researcher at the NEC Laboratories in Princeton, then at the University of Chicago's James Franck Institute. In 2003, he became a researcher at the Laboratory for Neutron Scattering (Swiss Federal Institute of Technology in Zurich) and at the Paul Scherrer Institute. In 2007 he was appointed Assistant Professor at Ecole Polytechnique federale de Lausanne (EPFL). In 2012 he was promoted to Associate Professor. Profession 2012- Associate Professor, Laboratory for Quantum Magnetism, EPFL, Switzerland 2007-2012 Assistant Professor, Laboratory for Quantum Magnetism, EPFL, Switzerland 2003-2006 Scientist, Laboratory for Neutron Scattering, ETH-Zürich & Paul Scherrer Institute, Switzerland 2002-2003 Visiting Scientist, NEC-Laboratories Inc., Princeton, and James Franck Institute, University of Chicago, USA 2000-2002 Marie Curie Fellowship funded by the EU, hosted by Commissariat à l'Energie Atomique, Grenoble, France 2000 Postdoc, Institut Laue-Langevin, Grenoble, France 1996 Research assistant, Risø National Laboratory, Denmark Education 2000 Ph.D. in Physics, Risø National Laboratory and University of Copenhagen: Aspects of quantum magnetism in one, two and three dimensions 1996 M.Sc. in Physics, University of Copenhagen: Magnetic properties of holmium-erbium alloys 1995 B.Sc in Mathematics, University of Copenhagen 1994 B.Sc in Physics, University of Copenhagen 1992 High school graduate, Natural Sciences, Scolae Academiae Sorana
André MerbachAndré Merbach was born in Lausanne in 1940. He studied at the Polytechnical School of the University of Lausanne (Pelet and A3E2PL Awards), where he obtained in 1962 his degree in Chemical Engineering with a diploma research work in organic chemistry. In 1964, the University of Lausanne awarded him a PhD for his research on quaternary solubility systems with formation of mixed crystals. He spent then a Postdoctoral Fellowship in the Lawrence Radiation Laboratory at the University of California, Berkeley, where he studied the ionisation of strong electrolytes by NMR.
Upon his return in 1965 to the Institute of Inorganic and Analytical Chemistry at the University of Lausanne, he was asked to create a research and teaching program in Coordination Chemistry. He was appointed Assistant Professor in 1971.
In 1973, the Swiss Chemical Society awarded him the Werner Prize and Medal for his research on the structure, the stability and the dynamics of metal halogen adducts by NMR and, the same year, was nominated Professor of Inorganic and Analytical Chemistry.
He was a member of the Swiss National Foundation for Scientific Research in the division of Mathematics, Natural Sciences and Engineering from 1985 until 1996. He represents Switzerland on the COST Chemistry Technical Committee (European Co-operation in the Field of Scientific and Technical Research: 35 countries and 1000 research groups in chemistry) and has chaired this Committee from 1998 to 2000. He was the Chairman of the Management Committee of the COST Action D6 on Chemical Processes and Reactions under Extreme or Non-Classic Conditions (1992-1997).
He has organised the XXIXth International Conference in Coordination Chemistry (ICCC) in Lausanne in 1992. He has been awarded an honoris causa doctorate from the Lajos Kossuth University of Debrecen (Hungary) in 1993 for his work on elucidating reaction mechanisms in coordination chemistry utilising high pressure NMR. He has been called at the presidency of the Swiss Chemical Society (2001-2004). The University of Geneva awarded him an honoris causa doctorate in 2003.
Theo LasserDe nationalité allemande, né en 1952 à Lauchheim (Baden-Württemberg). Après des études de physique à l'Université Fridericiana de Karlsruhe, il y obtient son diplôme de physique en 1978.
En 1979, il rejoint l'Institut de Recherches franco-allemand à Saint-Louis (France) comme collaborateur scientifique. En 1986, il rejoint la division de recherche de Carl Zeiss à Oberkochen (Allemagne) où il développe principalement divers systèmes laser pour des applications médicales. Dès 1990, il dirige le laboratoire laser de la division médicale. En 1993, il prend la direction de l'unité "laser d'ophtalmologie". Dès le début 1995, il est chargé de restructurer et regrouper les nombreuses activités d'ophtalmologie chez Carl Zeiss et de les transférer à Jena. Durant cette période, il réalise des nouveaux instruments de réfraction, des biomicroscopes et des caméras rétiniennes.
Dès janvier 1998, il dirige la recherche de Carl Zeiss à Jena où il initie de nouveaux projets en microscopie, en microtechnique et en recherche médicale. En juillet 1998, il est nommé professeur ordinaire en optique biomédicale à l'Institut d'optique appliquée. Au sein du Département de microtechnique, son activité de recherche porte sur la photonique biomédicale. Il participe à l'enseignement d'optique et d'instrumentation biomédicale.
Short CV
1972 Physics University of Karlsruhe (Germany)
1979 l'Institut de Recherches franco-allemand à Saint-Louis (France)
1986 central research division Carl Zeiss, Oberkochen (Germany)
1990 Med - Division, ophthalmic lasers
1994 Ophthalmology division, Carl Zeiss Jena
1998 Head of Central research Carl Zeiss Jena
1998 full Professor Ecole Polytechnique Federale Lausanne, Switzerland
Mor-Miri MishkovskyI am a chemist, graduated Cum Laude in 2002 from Tel Aviv University in Israel. I obtained a PhD in Physical Chemistry from the Weizmann Institute of Science in Israel on the development of new technology for rapid detection of nuclear magnetic resonance (NMR) spectroscopic data aiming at reducing the measurement time from hours to a fraction of second with Prof. Lucio Frydman. My thesis “Methodological Developments in Ultrafast Multidimensional NMR” granted me the Auto Swartz excellence award in 2007. Since 2009 I am working with the Laboratory of Functional and Metabolic Imaging at the École Polytechnique Fédérale de Lausanne (EPFL), Switzerland, on the development of hyperpolarized (HP) magnetic resonance spectroscopy (MRS) methodologies for monitoring biochemical processes in real-time.My research is focused on the development of Magnetic Resonance (MR) Molecular Imaging by dissolution dynamic nuclear polarization (dDNP). HP agents to interrogate biochemical processes in real-time are applied in vivo in the healthy brain and disease models, aiming at improving our understanding of cerebral function and metabolism toward better clinical diagnostics and therapy.
