Publications related to Obstructive sleep apnea

Robust tunable acoustic impedance control on electroacoustic resonators for aircraft noise reduction

Air traffic noise emissions are responsible for a significant part of the overall environmental noise, especially in the vicinity of airports. Exposure to environmental noise is known to negatively impact health and to be associated with cardiovascular dis ...

EPFL2023

Novel Methods For Detection And Analysis Of Atypical Aspects In Speech

Julian David Fritsch

Atypical aspects in speech concern speech that deviates from what is commonly considered normal or healthy. In this thesis, we propose novel methods for detection and analysis of these aspects, e.g. to monitor the temporary state of a speaker, diseases tha ...

EPFL2023

Associations between urinary biomarkers of oxidative stress and biomarkers of tobacco smoke exposure in smokers

Florian Frédéric Vincent Breider, Dominique Grandjean, Nicolas Sambiagio

Oxidative stress can contribute to the development of diseases, and may originate from exposures to toxicants commonly found in air pollution and cigarette smoke such as polycyclic aromatic hydrocarbons (PAHs) and volatile organic compounds (VOCs). Yet, as ...

Elsevier2022

Genetic selection for low glucocorticoid responsiveness recapitulates PTSD-related phenotypes: a behavioral, neuroimaging and sleep-physiology study

Silvia Monari

Humans show inter-individual differences in vulnerability to develop post-traumatic stress disorder (PTSD) following exposure to trauma. Several critical biobehavioral features have been consistently described in PTSD patients, including blunted cortisol l ...

EPFL2022

Contactless Sleep Monitoring for Early Detection of Health Deteriorations in Community-Dwelling Older Adults: Exploratory Study

Daniel Gatica-Perez, Philipp Buluschek, Bruno Pais

Background: Population aging is posing multiple social and economic challenges to society. One such challenge is the social and economic burden related to increased health care expenditure caused by early institutionalizations. The use of modern pervasive ...

JMIR PUBLICATIONS, INC2021

Sleep disturbance-related depressive symptom and brain volume reduction in shift-working nurses

Chang-Hyun Park

Disturbed sleep is the most common effect of shift work. A large corpus of research indicates an association between sleep disturbance and depressive symptom in shift workers. In this study, we proposed the mediating role of grey matter (GM) structure in t ...

Nature Research2020

Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans

Johan Auwerx, Richardus Houtkooper

Background: Nicotinamide riboside (NR) is an NAD(+) precursor that boosts cellular NAD(+) concentrations. Preclinical studies have shown profound metabolic health effects after NR supplementation. ...

OXFORD UNIV PRESS2020

Mechanisms of the breathing contribution to bodily self‐consciousness in healthy humans: Lessons from machine‐assisted breathing?

Olaf Blanke, Bruno Herbelin, Oliver Alan Kannape, Javier Bello Ruiz, Elisa Canzoneri, Sophie Jacqueline Andrée Betka

Previous studies investigated bodily self‐consciousness (BSC) by experimentally exposing subjects to multisensory conflicts (i.e., visuo‐tactile, audio‐tactile, visuo‐cardiac) in virtual reality (VR) that involve the participant's torso in a paradigm known ...

Wiley2020

Non-invasive pulmonary artery pressure estimation by electrical impedance tomography in a controlled hypoxemia study in healthy subjects

Jean-Philippe Thiran, Mathieu Lemay, Fabian Braun, Martin Proença

Pulmonary hypertension is a hemodynamic disorder defined by an abnormal elevation of pulmonary artery pressure (PAP). Current options for measuring PAP are limited in clinical practice. The aim of this study was to evaluate if electrical impedance tomograp ...

NATURE RESEARCH2020

Low Power Sensing and Processing in Wearable Biomedical Devices for Personalized Health Monitoring

Grégoire Casimir Joseph Surrel

Whether it is for personal use or for medical application, wearable sensors are becoming more and more widespread. This is the industry answer to two parallel trends. First, the public show a wish to collect data about their own lifestyle. This rather new ...

EPFL2019

Sleep-wake-driven and circadian contributions to daily rhythms in gene expression and chromatin accessibility in the murine cortex

Felix Naef, Maxime Jan, Jake Yeung, Ioannis Xenarios

The timing and duration of sleep results from the interaction between a homeostatic sleep-wake-driven process and a periodic circadian process, and involves changes in gene regulation and expression. Unraveling the contributions of both processes and their ...

National Academy of Sciences2019

Online Obstructive Sleep Apnea Detection on Medical Wearable Sensors

David Atienza Alonso, Amir Aminifar, Francisco Javier Rincon Vallejos, Srinivasan Murali, Grégoire Casimir Joseph Surrel

Obstructive Sleep Apnea (OSA) is one of the main under-diagnosed sleep disorder. It is an aggravating factor for several serious cardiovascular diseases, including stroke. There is, however, a lack of medical devices for long-term ambulatory monitoring of ...

2018

Spatial clusters of daytime sleepiness and association with nighttime noise levels in a Swiss general population (GeoHypnoLaus)

Stéphane Joost, Idris Guessous, Rebecca Himsl

INTRODUCTION: Daytime sleepiness is highly prevalent in the general adult population and has been linked to an increased risk of workplace and vehicle accidents, lower professional performance and poorer health. Despite the established relationship between ...

2018

Can Daytime Napping Assist the Process of Skills Acquisition After Stroke?

Friedhelm Christoph Hummel, Winifried Backhaus

Acquisition and reacquisition of skills is a main pillar of functional recovery after stroke. Nighttime sleep has a positive influence on motor learning in healthy individuals, whereas the effect of daytime sleep on neuro-rehabilitative training and relear ...

2018

Signal Processing Approaches for Cardio-Respiratory Biosignals with an Emphasis on Mobile Health Applications

Leila Mirmohamadsadeghi

We humans are constantly preoccupied with our health and physiological status. From precise measurements such as the 12-lead electrocardiograms recorded in hospitals, we have moved on to mobile acquisition devices, now as versatile as smart-watches and sma ...

EPFL2017

Bright Light Delights: Effects of Daily Light Exposure on Emotions, Rest-activity Cycles, Sleep and Melatonin Secretion in Severely Demented Patients

Jean-Louis Scartezzini

Objective: We tested whether the effects of a dynamic lighting system are superior to conventional lighting on emotions, agitation behaviour, quality of life, melatonin secretion and circadian restactivity cycles in severely demented patients. As a compari ...

Bentham Science Publ Ltd2017

Sleep Disordered Breathing During Live High-Train Low in Normobaric Versus Hypobaric Hypoxia

Jean-Marc Vesin, Sibylle Fallet, Grégoire Millet, Mattia Bertschi

The present study aimed to compare sleep disordered breathing during live high-train low (LHTL) altitude camp using normobaric hypoxia (NH) and hypobaric hypoxia (HH). Sixteen highly trained triathletes completed two 18-day LHTL camps in a crossover design ...

Mary Ann Liebert, Inc2016

Sleep fragmentation alters brain energy metabolism without modifying hippocampal electrophysiological response to novelty exposure

Pierre Magistretti, Jean-Marie Petit, Maxime Olivier Baud

Sleep is viewed as a fundamental restorative function of the brain, but its specific role in neural energy budget remains poorly understood. Sleep deprivation dampens brain energy metabolism and impairs cognitive functions. Intriguingly, sleep fragmentatio ...

Wiley-Blackwell2016

On the Impact of Integration of Non-Image Forming (NIF) Effect of Light on Electrical Lighting Control in Non-Residential Buildings

Jean-Louis Scartezzini, Ali Motamed, Marta Benedetti

Lighting has an impact on the visual as well as cognitive performance of people in non-residential buildings. Light is the most powerful time cue for resetting the circadian pacemaker and ensuring correct synchronization of the internal clock with the envi ...

2016

Sustained Sleep Fragmentation Induces Sleep Homeostasis in Mice

Pierre Magistretti, Jean-Marie Petit, Maxime Olivier Baud

Study Objectives: Sleep fragmentation (SF) is an integral feature of sleep apnea and other prevalent sleep disorders. Although the effect of repetitive arousals on cognitive performance is well documented, the effects of long-term SF on electroencephalogra ...

American Academy of Sleep Medicine2015