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Genetic Instability: De Palma
Explores genetic instability in cancer, multi-step progression, repair mechanisms, and cancer stem cells.
DNA Mutations: Mechanisms and Consequences
Explores DNA mutation mechanisms, including replication errors and induced mutations by mutagens, emphasizing their role in genetic diversity.
Multi-step Tumor Progression: De Palma
Explores the multi-step progression of tumors, from cancer incidence rates to tumor initiators and promoters.
DNA Replication and Cancer
Explores the link between DNA replication, DNA repair mechanisms, and cancer development.
Molecular Evolution: Mutations and Genetic Diversity
Explores mutations, genetic diversity, and horizontal gene transfer, emphasizing the impact of errors during replication and exposure to mutagens.
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