Publications related to Human tooth development

Customized modular multi-material mouthguard and method of making the same

Dominique Pioletti, Naser Nasrollahzadeh Mamaghani, Martin Broome

There is described a mouthguard comprising an externally exposed impact protective region defined by a first material property and configured to cover a front tooth, an internally exposed occlusional cushioning region defined by a second material property ...

2024

Design of Customized Mouthguards with Superior Protection Using Digital-Based Technologies and Impact Tests

Dominique Pioletti, Naser Nasrollahzadeh Mamaghani, Martin Broome

Background In contact sports, an impact on the jaw can generate destructive stress on the tooth-bone system. Mouthguards can be beneficial in reducing the injury risk by changing the dynamics of the trauma. The material properties of mouthguards and their ...

Springer2024

Evidence of a transient phase during the hydrolysis of calcium-deficient hydroxyapatite

Jacques Lemaître

In the present paper, calcium deficient hydroxyapatite (Ca-def OHAP) has been examined in a transmission electron microscope. During the observation, the initial Ca-def OHAP was seen to transform first into a transient intermediate phase, then to a final, ...

WALTER DE GRUYTER GMBH2022

Scaffold requirements for periodontal regeneration with enamel matrix derivative proteins

John Christopher Plummer, Laurent Mirko Dejace, Matteo Gregorio Modesto Marascio, Alessandra Apicella, Peter Fischer

Periodontitis affects the attachment of natural teeth, and infection or inflammation associated with periodontitis may affect peri-implant tissues. Enamel matrix derivative (EMD) proteins provide stimulation for self-regeneration of the damaged tissue when ...

Elsevier Science Bv2017

Molecular dynamics simulations of the intrinsically disordered protein amelogenin

John Christopher Plummer, Matteo Gregorio Modesto Marascio, Alessandra Apicella, Vincenzo Colangelo

Amelogenin refers to a class of intrinsically disordered proteins that are the major constituents of enamel matrix derivative (EMD), an extract of porcine fetal teeth used in regenerative periodontal therapy. Modifications in molecular conformation induced ...

Taylor & Francis Inc2017

The merits of ion cyclotron heating schemes for sawtooth control in tokamak plasmas

Jonathan Graves, Jonathan Marc Philippe Faustin

JET experiments have compared the efficacy of low-and high field side ion cyclotron resonance heating (ICRH) as an actuator to deliberately minimise the sawtooth period. It is found that low-field side ICRH with low minority concentration is optimal for sa ...

Cambridge University Press2015

Strontium hydroxyapatite and strontium carbonate as templates for the precipitation of calcium-phosphates in the absence and presence of fluoride

Janet Gordon Hering, Michèle Bernadette Heeb

The heterogeneous precipitation of calcium phosphates on calcium hydroxyapariLe (Ca-10(PO4)(4)OH)(2) or HAP) in the presence arid absence of fluoride is important in the formation of bone and teeth, protection against tooth decay, dental and skeletal fluor ...

Elsevier Science Bv2014

Sputtered titanium oxynitride coatings for endosseous applications: Physical and chemical evaluation and first bioactivity assays

Rosendo Sanjines, Alessandro Pontearso

Titanium oxynitride coatings (TiNxO3,) are considered a promising material for applications in dental implantology due to their high corrosion resistance, their biocompatibility and their superior hardness. Using the sputtering technique, TiNxO3, films wit ...

Elsevier Science Bv2014

Detection and Strain Typing of Ancient Mycobacterium leprae from a Medieval Leprosy Hospital

Stewart Cole, Pushpendra Singh

Nine burials excavated from the Magdalen Hill Archaeological Research Project (MHARP) in Winchester, UK, showing skeletal signs of lepromatous leprosy (LL) have been studied using a multidisciplinary approach including osteological, geochemical and biomole ...

Public Library of Science2013

Surface Modification of Biomaterials for Conjugation with Human Fetal Osteoblasts

Sandrine Gerber, Davide Städler, Françoise Borcard, Céline Marie Anne Journot, Phally Kong

Surface functionalization of hydroxyapatite (HA) and β-tricalcium phosphate (TCP) bioceramics with chemical ligands containing a pyrrogallol moiety was developed to improve the adhesion of bone cell precursors to the biomaterials. Fast and biocompatible co ...

Swiss Chemical Soc2013

Patterning and shaping the endoderm in vivo and in culture

Anne Grapin-Botton, Marine Marie Kraus

The definitive endoderm (DE) was first defined as the innermost germ layer found in all metazoan embryos. During development, it gives rise to a vast array of specialized epithelial cell types lining the respiratory and digestive systems, and contributes t ...

Elsevier2012

Functionalization of microstructured open-porous bio-ceramic scaffolds with human fetal cells

Sandrine Gerber, Corinne Scaletta, Davide Städler, Françoise Borcard

Bone substitute materials allowing trans-scaffold migration and in-scaffold survival of human bone-derived cells are mandatory for development of cell-engineered permanent implants to repair bone defects. In this study, we evaluated the influence on human ...

American Chemical Society2012

Immobilizing device for a toothed wheel

Simon Nessim Henein, Fabiano Colpo

The invention relates to an immobilizing device for a toothed wheel suitable for the field of horology where it can be part of a direct- or indirect-impulse escapement, in particular in a wristwatch. This immobilizing device (1, 2, 3, 4, 5, 6) comprises: — ...

European Patent Office2011

Covalent cell surface functionalization of human fetal osteoblasts for tissue engineering

Sandrine Gerber, Corinne Scaletta, Davide Städler, Aurélien Godinat, Françoise Borcard

The chemical functionalization of cell-surface proteins of human primary fetal bone cells with hydrophilic bioorthogonal intermediates was investigated. Toward this goal, chemical pathways were developed for click reaction-mediated coupling of alkyne deriv ...

2011

Three-dimensional morphometry of strained bovine periodontal ligament using synchrotron radiation-based tomography

John Botsis, Joël Cugnoni, Marzio Bergomi, Marco Stampanoni, Philipp Schneider

The periodontal ligament (PDL) is a highly vascularized soft connective tissue. Previous studies suggest that the viscous component of the mechanical response may be explained by the deformation-induced collapse and expansion of internal voids (i.e. chiefl ...

2010

Mechanical response of periodontal ligament: Effects of specimen geometry, preconditioning cycles and time lapse

John Botsis, Marzio Bergomi

This study was conducted as part of research line addressing the mechanical response of periodontal ligament (PDL) to tensile-compressive sinusoidal loading The aim of the present project was to determine the effect of three potential sources of variabilit ...

2009

Experimental and numerical investigations on the fluid contribution to the tensile-compressive mechanical behavior of the bovine periodontal ligament

Marzio Bergomi

Orthodontic treatments are all based on the experimental evidence that teeth can be forced to move in the dental arch by means of applied mechanical forces. Since it allows for prediction of dental mobility, the mechanical characterization of the tissues i ...

EPFL2008

Regional structural characteristics of bovine periodontal ligament samples and their suitability for biomechanical tests

Marzio Bergomi

Mechanical testing of the periodontal ligament requires a practical experimental model. Bovine teeth are advantageous in terms of size and availability, but information is lacking as to the anatomy and histology of their periodontium. The aim of this study ...

2008

Control of thrombin signaling through PI3K is a mechanism underlying plasticity between hair follicle dermal sheath and papilla cells

Yann Barrandon

In hair follicles, dermal papilla (DP) and dermal sheath (DS) cells exhibit striking levels of plasticity, as each can regenerate both cell types. Here, we show that thrombin induces a phosphoinositide 3-kinase (PI3K)-Akt pathway-dependent acquisition of D ...

Company of Biologists2008

An exact formula for "tooth-to-tooth" permeance

Yves Perriard, Marcel Jufer, Miroslav Markovic

We present a new, completely original exact method to determine the permeance between two opposing iron teeth. This configuration is important because it is often encountered in electrical machines and apparatus. The method is based on conformal mapping. T ...

Institute of Electrical and Electronics Engineers2005