Concept

Ligand (biochemistry)

Related lectures (32)

Ligand-Receptor Interactions: Mechanisms and Quantification

Covers ligand-receptor interactions, their mechanisms, and how to quantify binding affinities in biological systems.

Receptor-Ligand Interaction: Quantification and Mechanisms

Explores methods to quantify receptor-ligand interactions, ligand-gated ion channels, and the Hill equation.

Protein-Ligand Interactions: Importance and Affinity

Explores the importance of protein-ligand interactions, focusing on binding affinities and energetic landscapes, with implications for drug development and specificity.

Receptor Tyrosine Kinases: Signalling and Regulation

Explores the activation, signalling cascades, and regulatory mechanisms of receptor tyrosine kinases, with a focus on disease implications and therapeutic strategies.

Protein Folding: Forces and Mechanisms

Explores protein folding forces, including van der Waals interactions, hydrogen bonds, and salt bridges, and their impact on stability.

Pharmacodynamics: Acid-sensing ion channels and Drug Targets

Explores acid-sensing ion channels, drug targets, and ligand-receptor binding.

Protein-Ligand Interactions

Explores the principles of protein-ligand interactions, covering methods for measuring affinity and kinetics in drug development.

Pharmacodynamics: Ligand-Receptor Binding Kinetics

Explores ligand-receptor binding kinetics, concentration-effect relationship, and drug therapy impact.

Receptor-Ligand Interaction

Explores receptor-ligand interactions, covering binding, dissociation, equilibrium, and quantification methods.

Molecular Binding Assays: Aptamers and Binders Selection

Covers selecting aptamers and binders based on binding affinities and additional properties for downstream testing.

Pharmacodynamics: Quantitative Description of Ligand-Receptor Binding

Delves into the quantitative aspects of ligand-receptor binding and receptor occupancy.

Complexation Chemistry

Covers the thermodynamics of complexation chemistry, explaining metal-ligand complexes and the role of ligands in the environment.

Protein-Ligand Interactions

Explores protein-ligand interactions, covering binding affinity, energetics, and various experimental techniques used to study them.

Pharmacodynamics: Ligand-Receptor Interactions and Drug Effects

Explores ligand-receptor interactions, drug effects, modulation mechanisms, and factors influencing drug responses.

Complexation Chemistry: Principles and Applications

Explores complexation chemistry principles, metal-ligand interactions, toxicity mechanisms, and environmental implications.

Inhibitor Design & Analysis

Covers the design and analysis of inhibitors for next-generation covalent drugs, focusing on target engagement and the importance of cysteine targeting.

Nuclear Receptors: Core Signaling

Explores nuclear receptors' core signaling and the impact of endocrine disruptors on the endocrine system, including the inhibitory effects of compounds like eugenol on the estrogen receptor.

Nucleophilic Attack on M-alkene

Covers the nucleophilic attack on M-alkene and ligand association in different reaction mechanisms.

Nuclear Receptors: Signalling and Health Implications

Explores nuclear receptors, JAK-STAT pathway, growth factors, endocrine disruptors, and estrogen receptors.

Design Optimization in ChemBio

Explores the design optimization of sensors and bioluminescent proteins for drug monitoring and metabolite visualization.