Lectures related to Oncogene | EPFL Graph Search

Cancer Biology: Hallmarks and Mechanisms

Covers the hallmarks of cancer, oncogenes, DNA repair, telomeres, viruses, cell cycle, stem cells, metastasis, and genetic instability.

Evading Growth Suppression: TGFB Signaling

Explores how cells evade growth suppression, focusing on TGFB signaling and the role of tumor suppressors like PTEN and p53.

Cancer Biology: Hallmarks and Mechanisms

Covers the hallmarks of cancer, oncogenes, tumor suppressor genes, metastasis, and genetic alterations driving tumorigenesis.

Understanding Cancer Genetics

Explores genetic and epigenetic changes in cancer cells and the impact of carcinogens.

Altered Metabolism in Cancer: Warburg Effect and MYC Regulation

Explores altered cancer metabolism, MYC regulation, Rb and p53 pathways, AKT re-activation, and protein-protein interactions.

DNA Repair Mechanisms

Explores DNA repair mechanisms, DNA damage response, and synthetic lethality in cancer.

Virus and Cell Proliferation

Delves into how viruses aid in understanding cell proliferation control mechanisms and gene expression regulation for the S phase.

DNA Damage Response and Tumor Suppressor Genes

Delves into DNA damage response, tumor suppressor genes, and mutant P53 in cancer.

Cancer Biology: p53 and DNA Repair

Explores p53's pivotal role in cellular stability, DNA repair, and tumor suppression, emphasizing TP53 mutations and DNA double-strand break repair mechanisms.

Cellular Senescence and Tumor Progression

Explores cellular senescence, oncogene activation, DNA damage response, and telomere dysfunction in cancer suppression pathways.

Cellular Senescence: Mechanisms and Implications

Explores cellular senescence mechanisms induced by mitogenic signals, DNA damage, and oncogenes, emphasizing the role of key regulatory proteins and the impact on cell division.

Metabolic Signaling: Challenges & Future Directions

Explores metabolic signaling, the Warburg effect, and pathway rewiring in proliferating cells.

Mutations and Cancer: The Role of P53 and HPV

Covers mutations, the role of P53 in cancer, and HPV's impact on tumorigenesis.

Genetic Inheritance and Molecular Analysis

Explores genetic inheritance, molecular analysis, and disorders like colorblindness.

B-Cell Receptor Signaling in Lymphoma and Leukemia

Explores B-cell receptor signaling in lymphoma and leukemia, drug resistance mechanisms, CRISPR/Cas9 gene editing, mTOR inhibitors, cell cycle inhibition, and undruggable oncogenes.

Genetic Mutations: Causes and Effects

Explores genetic mutations, chromosomal abnormalities, DNA repair, and disease implications.

Altered Pathways in Cancer: Signaling Cascades and Mutations

Explores cancer pathways, major signaling cascades, and mutations in RAS and BRAF genes.

Selective Drug Targeting Mechanisms

Explores selective drug targeting mechanisms, resistance development, tuberculosis incidence, BCR-ABL mutations, tyrosine kinase inhibitors, drug toxicity, interactions, and toxicology studies.

General Topics of Pharmacology: Mechanisms and Toxicity

Explores selective targeting in chemotherapy, drug resistance mechanisms, and drug toxicity.