Publications related to Optic neuritis

Fabrication and validation of an intraneural interface tailored for optic nerve stimulation

Technological progress in materials science and microengineering along with new discoveries in neuroscience have contributed to restore lost or impaired sensory functions by closely interfacing with the nervous system. Electronic devices have begun to be i ...

EPFL2022

A machine-learning algorithm correctly classifies cortical evoked potentials from both visual stimulation and electrical stimulation of the optic nerve

Diego Ghezzi, Eleonora Borda, Vivien Gaillet, Elodie Geneviève Zollinger

Objective. Optic nerve's intraneural stimulation is an emerging neuroprosthetic approach to provide artificial vision to totally blind patients. An open question is the possibility to evoke individual non-overlapping phosphenes via selective intraneural op ...

IOP PUBLISHING LTD2021

Clinical and Genetic Findings of Autosomal Recessive Bestrophinopathy (ARB)

Imen Habibi

Mutations in BEST1 cause several phenotypes including autosomal dominant (AD) Best vitelliform macular dystrophy type 2 (BVMD), AD vitreo-retino-choroidopathy (ADVIRC), and retinitis pigmentosa-50 (RP50). A rare subtype of Bestrophinopathy exists with bial ...

2019

Personalized Anatomic Eye Model From T1-Weighted Volume Interpolated Gradient Echo Magnetic Resonance Imaging of Patients With Uveal Melanoma

Meritxell Bach Cuadra, Raphael Sznitman, Alessia Pica

Purpose: We present a 3-dimensional patient-specific eye model from magnetic resonance imaging (MRI) for proton therapy treatment planning of uveal melanoma (UM). During MRI acquisition of UM patients, the point fixation can be difficult and, together with ...

ELSEVIER SCIENCE INC2018

Comparison of acute non-visual bright light responses in patients with optic nerve disease, glaucoma and healthy controls

Lorette Leon

This study examined the effect of optic nerve disease, hence retinal ganglion cell loss, on nonvisual functions related to melanopsin signalling. Test subjects were patients with bilateral visual loss and optic atrophy from either hereditary optic neuropat ...

Nature Publishing Group2015

Automatic Segmentation of the Eye in 3D Magnetic Resonance Imaging: A Novel Statistical Shape Model for Treatment Planning of Retinoblastoma

Jean-Philippe Thiran, Meritxell Bach Cuadra, Raphael Sznitman, Carlos Ciller, Alessia Pica

Purpose: Proper delineation of ocular anatomy in 3-dimensional (3D) imaging is a big challenge, particularly when developing treatment plans for ocular diseases. Magnetic resonance imaging (MRI) is presently used in clinical practice for diagnosis confirma ...

Elsevier Science Inc2015

Retinal prostheses: progress toward the next generation implants

Diego Ghezzi

In the last decade, various clinical trials proved the capability of visual prostheses, in particular retinal implants, to restore a useful form of vision. These encouraging results promoted the emerging of several strategies for neuronal stimulation aimin ...

Frontiers Research Foundation2015

Landmark Detection for Fusion of Fundus and MRI Toward a Patient-Specific Multimodal Eye Model

Meritxell Bach Cuadra, Carlos Ciller

Ophthalmologists typically acquire different image modalities to diagnose eye pathologies. They comprise, e.g., Fundus photography, optical coherence tomography, computed tomography, and magnetic resonance imaging (MRI). Yet, these images are often complem ...

Ieee-Inst Electrical Electronics Engineers Inc2015

Pupil responses derived from outer and inner retinal photo reception are normal in patients with hereditary optic neuropathy

Mirjam Münch, Lorette Leon

We compared the pupil responses originating from outer versus inner retinal photoreception between patients with isolated hereditary optic neuropathy (HON, n = 8) and healthy controls (n = 8). Three different testing protocols were used. For the first two ...

Academic Press Ltd- Elsevier Science Ltd2014

Chiasmatic Infiltration Secondary to Late Malignant Transformation of Retinoma

Alessia Pica

Purpose: To report the lethal course of malignant transformation of retinoma in an adult. Methods: Case report. A 40-year-old patient presented with retinoma in his right eye and retinoblastoma in his left eye. Enucleation was recommended but refused and t ...

Informa Healthcare2012

Tomographie en cohérence optique dans le domaine de Fourier appliquée aux tissus humains

Roland Michaely

Fourier Domain Optical Coherence Tomography FDOCT is a recent imaging technique based on the principle of Low Coherence Interferometry. In FDOCT cross-sectional images of diffusing objects are synthesised from a measure of backscattered light. The main adv ...

EPFL2008

Vectorial retinal blood flow and optical vessel vivisection for 3D angiography with high resolution resonant Doppler OCT

Theo Lasser, Martin Villiger, Rainer Leitgeb, Cédric Blatter, Adrian Bachmann, Roland Michaely

PURPOSE: To perform high speed and completely non-invasive 3D angiography at the optic nerve head region and to reconstruct vectorial 3D blood flow from optically segmented blood vessel structure as a pre-requisite for testing retinal function and physiolo ...

2007