Publications related to Fish disease and parasites

Identification of the trade-off between speed and efficiency in undulatory swimming using a bio-inspired robot

Auke Ijspeert, Karen Ann J Mulleners, Laura Isabel Paez Coy, Kamilo Andres Melo Becerra, Alexandros Anastasiadis, Eric Daniel Tytell

Anguilliform swimmers, like eels or lampreys, are highly efficient swimmers. Key to understanding their performances is the relationship between the body’s kinematics and resulting swimming speed and efficiency. But, we cannot prescribe kinematics to livin ...

Nature Research2023

The Bioaccumulation of Ionizable Organic Compounds in Fish Cell Lines

Fabian Gerhard Peter Balk

Bioaccumulation is defined as the enrichment of a compound in an organism relative to the surrounding water or its food, and is an important endpoint in chemical risk assessment. Under laboratory conditions, bioaccumulation is measured as bioconcentration ...

EPFL2023

Predicting exposure concentrations of chemicals with a wide range of volatility and hydrophobicity in different multi-well plate set-ups

Kristin Schirmer, Julita Maria Stadnicka-Michalak

Quantification of chemical toxicity in small-scale bioassays is challenging owing to small volumes used and extensive analytical resource needs. Yet, relying on nominal concentrations for effect determination maybe erroneous because loss processes can sign ...

NATURE RESEARCH2021

Toxicity and translocation of Ag, CuO, ZnO and TiO2 nanoparticles upon exposure to fish intestinal epithelial cells

Kristin Schirmer, Laura Sigg

Understanding the ability of fish intestinal cells to act as a barrier for nanoparticle (NP) uptake and their effects is of significance from an environmental perspective as well as for human health, for which fish serves as an important nutrient source. W ...

ROYAL SOC CHEMISTRY2021

Characterization of the ERK1/2 phosphorylation profile in human and fish liver cells upon exposure to chemicals of environmental concern

Kristin Schirmer, Jelena Petrovic

We developed phospho-ERK1/2 ELISA for human and rainbow trout liver cells, employing HepG2 and RTL-W1 cell lines as models. The assay was applied to detect changes in ERK1/2 activity for nine chemicals, added over a wide concentration range and time points ...

ELSEVIER2021

Automated flow control of a multi-lane swimming chamber for small fishes indicates species-specific sensitivity to experimental protocols

In fishes, swimming performance is considered an important metric to measure fitness, dispersal and migratory abilities. The swimming performance of individual larval fishes is often integrated into models to make inferences on how environmental parameters ...

2021

Legacy and alternative halogenated flame retardants in Lake Geneva fish

Benoît Jean Dominique Ferrari

Legacy (i.e., polybrominated diphenyl ethers (PBDEs) and hexabromocyclododecane (HBCDD)) and alternative halogenated flame retardants (HFRs) were analyzed in 31 whole fish samples from Lake Geneva in 2018. Two fish species, namely, the burbot (Lota lota) a ...

2021

Strategies to modulate zebrafish collective dynamics with a closed-loop biomimetic robotic system

Francesco Mondada, Alexey Gribovskiy, Frank Bonnet

The objective of this study is to integrate biomimetic robots into small groups of zebrafish and to modulate their collective behaviours. A possible approach is to have the robots behave like sheepdogs. In this case, the robots would behave like a differen ...

2020

Stream Temperature Evolution in Switzerland: Recent past and future

Michael Lehning, Wolf Hendrik Huwald, Adrien Michel, Bettina Schaefli, Nander Wever, Tristan Jonas Brauchli

Climate change has already affected many components of our natural environment which are well described in the literature. Water temperature has received less interest despite the fact that it is recognized as key variable for assessing water quality of fr ...

2020

Intestinal Fish Cell Barrier Model to Assess Transfer of Organic Chemicals in Vitro: An Experimental and Computational Study

Kristin Schirmer, Hannah Inka Schug, Anze Zupanic, Jenny Maner

We studied the role of the fish intestine as a barrier for organic chemicals using the epithelial barrier model built on the rainbow trout (Oncorhynchus mykiss) intestinal cell line, RTgutGC and the newly developed exposure chamber, TransFEr, specifically ...

AMER CHEMICAL SOC2019

Improving a fish intestinal barrier model by combining two rainbow trout cell lines: epithelial RTgutGC and fibroblastic RTgutF

Philippe Renaud, Kristin Schirmer, Carolin Drieschner, Hannah Inka Schug

An in vitro model of the fish intestine is of interest for research and application in diverse fields such as fish physiology, aquaculture and chemical risk assessment. The recently developed epithelial barrier model of the fish intestine relies on the RTg ...

Springer2019

Sex-specific changes in gene expression in response to estrogen pollution around the onset of sex differentiation in grayling (Salmonidae)

Oliver Michele Selmoni

The synthetic 17 alpha-ethinylestradiol (EE2) is a common estrogenic pollutant that has been suspected to affect the demography of river-dwelling salmonids. One possibility is that exposure to EE2 tips the balance during initial steps of sex differentiatio ...

2019

Fish-gut-on-chip: development of a microfluidic bioreactor to study the role of the fish intestine in vitro

Philippe Renaud, Kristin Schirmer, Sarah-Katharina Könemann, Carolin Drieschner

In this study we present the first fish-gut-on-chip model. This model is based on the reconstruction of the intestinal barrier by culturing two intestinal cell lines from rainbow trout, namely epithelial RTgutGC and fibroblastic RTgutF, in an artificial mi ...

2019

A fish intestinal barrier model to assess the interaction with chemicals in vitro

Hannah Inka Schug

The intestinal epithelium acts as vital gate keeper between the fish and its surrounding environment. A single layer of connected epithelial cells forms a selective barrier, which, among other essential functions, is important for nutrient uptake and defen ...

EPFL2019

Ecohydrological and Metacommunity Studies of Proliferative Kidney Disease Spread in Freshwater Salmonid Fish

Luca Carraro

Proliferative kidney disease (PKD) is a high-mortality pathology affecting freshwater salmonid populations in Europe and North America. Its causative agent, the myxozoan Tetracapsuloides bryosalmonae, has a complex life-cycle exploiting freshwater bryozoan ...

EPFL2018

Spread of proliferative kidney disease in fish along stream networks: A spatial metacommunity framework

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Luca Carraro, Marino Gatto

Proliferative kidney disease (PKD) is a high-mortality pathology that critically affects freshwater salmonid populations. Infection is caused by the endoparasitic myxozoan Tetracapsuloides bryosalmonae, which exploits freshwater bryozoans as primary hosts. ...

2018

What is the role of fish intestine as environment-organism barrier? Mechanistic investigations using fish intestinal cells on a chip

Carolin Drieschner

The gut of fish belongs to the most essential barriers that mark the border between the organism and its surrounding environment. The pivotal barrier function, allowing to absorb nutrients from the diet while simultaneously protecting the organism from pat ...

EPFL2018

Sex differentiation in grayling (Salmonidae) goes through an all-male stage and is delayed in genetic males who instead grow faster

Oliver Michele Selmoni

Fish populations can be threatened by distorted sex ratios that arise during sex differentiation. Here we describe sex differentiation in a wild grayling (Thymallus thymallus) population that suffers from distorted sex ratios. We verified that sex determin ...

Springer Nature2017

Dose-dependent effects of morphine on lipopolysaccharide (LPS)-induced inflammation, and involvement of multixenobiotic resistance (MXR) transporters in LPS efflux in teleost fish

Kristin Schirmer

Opioid drugs, such as morphine (MO), detected in aquatic environments worldwide, may harm fish due to their semi-persistence and ability to potently interact with molecular targets conserved across vertebrates. Here, we established a waterborne bacterial l ...

Elsevier Sci Ltd2017

Interaction of silver nanoparticles with algae and fish cells: a side by side comparison

Kristin Schirmer, Laura Sigg, Renata Behra, Yang Yue, Xiaomei Li

Background: Silver nanoparticles (AgNP) are widely applied and can, upon use, be released into the aquatic environment. This raises concerns about potential impacts of AgNP on aquatic organisms. We here present a side by side comparison of the interaction ...

Biomed Central Ltd2017