Covers posttranslational modifications, focusing on phosphorylation and protein phosphatases, and explains kinase specificity assays and the optimal phosphorylation consensus.
Explores the activation, signalling cascades, and regulatory mechanisms of receptor tyrosine kinases, with a focus on disease implications and therapeutic strategies.
Explores kinase inhibitors, their types, mechanisms, and experimental evaluation, emphasizing the significance of covalent drugs in modern pharmaceutical research.
Covers sustaining proliferation in cancer cells, growth factors, receptor tyrosine kinases, signal transduction, viral oncogenes, and therapeutic opportunities.
Analyzes a mutant DDX3 enzyme's ATPase activity and inhibitor development, covering RNA chaperones, crystal structures, and mass spectrometry-based protein profiling.
Covers proteomic applications in neuroscience, focusing on targeted analysis of cortical neurons and their developmental interactions with striatal neurons.
Explores receptors, ligands, and their role in signal transduction, including the activation of the immune system and the significance of multivalency in receptor-ligand interactions.
