Concept

P53

Related lectures (15)

Evading Growth Suppression: TGFB Signaling

Explores how cells evade growth suppression, focusing on TGFB signaling and the role of tumor suppressors like PTEN and p53.

Cancer Biology: p53 and DNA Repair

Explores p53's pivotal role in cellular stability, DNA repair, and tumor suppression, emphasizing TP53 mutations and DNA double-strand break repair mechanisms.

DNA Repair Mechanisms

Explores DNA repair mechanisms, DNA damage response, and synthetic lethality in cancer.

Cancer Biology: Base Excision Repair

Covers cancer biology topics on base excision repair, cellular responses to DNA damage, p53 regulation, and apoptosis mechanisms.

Replicative Immortality

Explores replicative immortality in cancer cells, focusing on telomere erosion, telomerase activity, and the role of p53 in maintaining genomic stability.

DNA Damage Response and Tumor Suppressor Genes

Delves into DNA damage response, tumor suppressor genes, and mutant P53 in cancer.

Tumor Suppressor p53

Explores the tumor suppressor gene p53, its functions, regulation, and implications for cancer.

DNA Damage Checkpoint

Explores the DNA damage checkpoint, cell cycle regulation, repair mechanisms, and key proteins involved.

Mutations and Cancer: The Role of P53 and HPV

Covers mutations, the role of P53 in cancer, and HPV's impact on tumorigenesis.

Cellular Senescence: Mechanisms and Implications

Explores cellular senescence mechanisms induced by mitogenic signals, DNA damage, and oncogenes, emphasizing the role of key regulatory proteins and the impact on cell division.

B-Cell Receptor Signaling in Lymphoma and Leukemia

Explores B-cell receptor signaling in lymphoma and leukemia, drug resistance mechanisms, CRISPR/Cas9 gene editing, mTOR inhibitors, cell cycle inhibition, and undruggable oncogenes.

Hints of Holography

Covers hints of holography, stress tensor for AdS, and asymptotic symmetry of AdS.

Genetic Mutations: Causes and Effects

Explores genetic mutations, chromosomal abnormalities, DNA repair, and disease implications.

Lp Spaces: Introduction

Introduces Lp spaces, covering norms, inequalities, and integrability of functions.

DNA Damage and Repair

Covers DNA damage types, repair mechanisms, UV-induced damage, survival curves, NER deficiency consequences, tumor suppressor genes, and cancer prevention.