We estimate the selection constant in the following geometric selection theorem by Pach: For every positive integer d, there is a constant such that whenever are n-element subsets of , we can find a point and subsets for every , each of size at least , suc ...
Generating matching meshes for problems with complex boundaries is often an intricate process, and the use of non-matching meshes appears as an appealing solution. Yet, enforcing boundary conditions on non-matching meshes is not a straightforward process, ...
For several computational problems in homotopy theory, we obtain algorithms with running time polynomial in the input size. In particular, for every fixed k >= 2, there is a polynomial-time algorithm that, for a 1-connected topological space X given as a f ...
We consider two basic problems of algebraic topology: the extension problem and the computation of higher homotopy groups, from the point of view of computability and computational complexity. The extension problem is the following: Given topological space ...
This paper features two main contributions. On the one hand, it gives an impressive survey on the progress on the diameter problem, including the breakthrough of the author with his disproof of the Hirsch conjecture among many other recent results. On the ...
In a seminal paper published in 1946, Erd ̋os initiated the investigation of the distribution of distances generated by point sets in metric spaces. In spite of some spectacular par- tial successes and persistent attacks by generations of mathe- maticians, ...
Bicyclic peptide ligands were found to have good binding affinity and target specificity. However, the method applied to generate bicyclic ligands based on phage-peptide alkylation is technically complex and limits its application to specialized laboratori ...