Explores kinase inhibitors, enzyme inhibition methods, transition state analog drugs, and the significance of covalent drugs in pharmaceutical research.
Delves into enzyme inhibition, reversible and irreversible binding, and covalent drugs, exploring drug modes of action and their impact on drug efficacy.
Covers enzyme inhibition mechanisms, drug modes of action, targeted protein degradation using PROTACs, and the bump-hole method for protein-ligand engineering.
Explores the impact of machine learning in understanding human diseases, focusing on historical significance, natural products discovery, and challenges in designer drugs.
