Explores the applications of embryonic stem cells in biomedical research, disease modeling, and potential therapeutic interventions, including the types of stem cells and the challenges they face.
Delves into pioneer transcription factors, chromatin organization, and cell fate transitions, showcasing examples of reprogramming and discussing the potential applications in regenerative medicine.
Explores the requirements of materials for tissue engineering, focusing on stem cells and biomaterials' role in controlling stem-cell fate and tissue regeneration.
Explores transcription factors in reprogramming somatic cells to induced pluripotent stem cells and the correlation between Hox gene expression and morphological boundaries.
Explores challenges in isolating intact cells, differential expression between nuclear and whole cell transcriptomes, and identifying transcriptomic cell types.
Explores early embryogenesis, ES cell differentiation, disease modeling, neuronal function, genome editing, 'minibrains', in vitro retina and intestine, single-cell analysis, and lineage tracing.