Publications related to Sleep state misperception

Genetic selection for low glucocorticoid responsiveness recapitulates PTSD-related phenotypes: a behavioral, neuroimaging and sleep-physiology study

Humans show inter-individual differences in vulnerability to develop post-traumatic stress disorder (PTSD) following exposure to trauma. Several critical biobehavioral features have been consistently described in PTSD patients, including blunted cortisol l ...

EPFL2022

How to assess alerting effects of daylight at the workplace? Learnings from semi-controlled studies

Marilyne Andersen, Victoria Eugenia Soto Magán

Daylight, in which we evolved, is naturally rich in the blue component of the spectrum and has key properties when it comes to impacts on body functioning. Current lifestyles are driving the emergence of a 24-hour society that spends most of the time indoo ...

2019

Sleep-wake-driven and circadian contributions to daily rhythms in gene expression and chromatin accessibility in the murine cortex

Felix Naef, Maxime Jan, Jake Yeung, Ioannis Xenarios

The timing and duration of sleep results from the interaction between a homeostatic sleep-wake-driven process and a periodic circadian process, and involves changes in gene regulation and expression. Unraveling the contributions of both processes and their ...

National Academy of Sciences2019

Spatial clusters of daytime sleepiness and association with nighttime noise levels in a Swiss general population (GeoHypnoLaus)

Stéphane Joost, Idris Guessous, Rebecca Himsl

INTRODUCTION: Daytime sleepiness is highly prevalent in the general adult population and has been linked to an increased risk of workplace and vehicle accidents, lower professional performance and poorer health. Despite the established relationship between ...

2018

Distinct locomotor control and awareness in awake sleepwalkers

Olaf Blanke, Oliver Alan Kannape

Sleepwalkers’ complex nocturnal behaviors have inspired fictional characters from Shakespeare’s Lady Macbeth to Polidori’s Vampyre to Cesare, the homicidal somnambulist in The Cabinet of Dr Caligari. Yet although the underlying pathophysiology of sleepwalk ...

Elsevier2017

Sleep fragmentation alters brain energy metabolism without modifying hippocampal electrophysiological response to novelty exposure

Pierre Magistretti, Jean-Marie Petit, Maxime Olivier Baud

Sleep is viewed as a fundamental restorative function of the brain, but its specific role in neural energy budget remains poorly understood. Sleep deprivation dampens brain energy metabolism and impairs cognitive functions. Intriguingly, sleep fragmentatio ...

Wiley-Blackwell2016

Sustained Sleep Fragmentation Induces Sleep Homeostasis in Mice

Pierre Magistretti, Jean-Marie Petit, Maxime Olivier Baud

Study Objectives: Sleep fragmentation (SF) is an integral feature of sleep apnea and other prevalent sleep disorders. Although the effect of repetitive arousals on cognitive performance is well documented, the effects of long-term SF on electroencephalogra ...

American Academy of Sleep Medicine2015

Ultra-Low Power Design of Wearable Cardiac Monitoring Systems

David Atienza Alonso, Giovanni Ansaloni, Francisco Javier Rincon Vallejos, Ruben Braojos Lopez, Srinivasan Murali, Hossein Mamaghanian, Alair Dias Junior

This paper presents the system-level architecture of novel ultra-low power wireless body sensor nodes (WBSNs) for real-time cardiac monitoring and analysis, and discusses the main design challenges of this new generation of medical devices. In particular, ...

IEEE/ACM Press2014

Ultra-Low Power Design of Wearable Cardiac Monitoring Systems

David Atienza Alonso, Giovanni Ansaloni, Francisco Javier Rincon Vallejos, Ruben Braojos Lopez, Srinivasan Murali, Hossein Mamaghanian, Alair Dias Junior

This paper presents the system-level architecture of novel ultra-low power wireless body sensor nodes (WBSNs) for real-time cardiac monitoring and analysis, and discusses the main design challenges of this new generation of medical devices. In particular, ...

IEEE2014

Dual orexin receptor antagonists - promising agents in the treatment of sleep disorders

Damien Lapray

Insomnia is a serious medical and social problem, its prevalence in the general population ranges from 9 to 35% depending on the country and assessment method. Often, patients are subject to inappropriate and therefore dangerous pharmacotherapies that incl ...

Cambridge Univ Press2014

The Impact of Light Including Non-Image Forming Effects on Visual Comfort

Apiparn Borisuit

Visual comfort at workplaces has often been considered in terms of discomfort glare, luminance distribution and task visibility. Besides visual effects, the lighting environment has also impact on human physiology and behaviour. These effects of light are ...

EPFL2013

Effects of prior light exposure on early evening performance, subjective sleepiness, and hormonal secretion

Jean-Louis Scartezzini, Mirjam Münch, Friedrich Linhart, Apiparn Borisuit

In sighted humans, light intensity, timing, exposure duration, and spectral composition of light are important to entrain the endogenous circadian pacemaker to the 24-h day-night cycle. We tested the impact of two realistic office lighting conditions durin ...

American Psychological Association2012

Circadian and Wake-Dependent Effects on the Pupil Light Reflex in Response to Narrow-Bandwidth Light Pulses

Lorette Leon

PURPOSE. Nonvisual light-dependent functions in humans are conveyed mainly by intrinsically photosensitive retinal ganglion cells, which express melanopsin as photopigment. We aimed to identify the effects of circadian phase and sleepiness across 24 hours ...

Association for Research in Vision and Ophthalmology2012

Sleep paralysis in narcolepsy: more than just a motor dissociative phenomenon?

Francesco Manni

Sleep paralyses are viewed as pure motor phenomena featured by a dissociated state in which REM-related muscle atonia coexists with a wakefulness state of full consciousness. We present a 59-year-old man diagnosed with narcolepsy experiencing sleep paralys ...

2012

The Impact of Sleep Fragmentation on Sleep Homeostasis, Brain and Peripheral Energy Metabolism and Spatial Learning

Maxime Olivier Baud

The quality of sleep has recently come to the forefront of public health concerns in industrialized nations. Indeed, voluntary sleep curtailment is widespread, sleep disorders are increasingly recognized and both correlate with the current epidemiology of ...

EPFL2011

Energy-Aware Traffic Engineering

Dejan Kostic, Nedeljko Vasic

Energy consumption of the Internet is already substantial and it is likely to increase as operators deploy faster equipment to handle popular bandwidth-intensive services, such as streaming and video-on-demand. Existing work on energy saving considers loca ...

2010

Making Cluster Applications Energy-Aware

Dejan Kostic, Nedeljko Vasic, Vincent Salzgeber, Martin Barisits

Power consumption has become a critical issue in large scale clusters. Existing solutions for addressing the servers' energy consumption suggest ``shrinking'' the set of active machines, at least until the more power-proport-ional hardware devices become a ...

2009

Adaptive wake and sleep detection for wearable systems

Walter Karlen

Sleep problems and disorders have a serious impact on human health and wellbeing. The rising costs for treating sleep-related chronic diseases in industrialized countries demands efficient prevention. Low-cost, wearable sleep / wake detection systems which ...

EPFL2009

Chloramphenicol decreases brain glucose utilization and modifies the sleep-wake cycle architecture in rats

Pierre Magistretti, Jean-Marie Petit

We studied the effects of chloramphenicol on brain glucose utilization and sleep-wake cycles in rat. After slightly anaesthetized animals were injected with [18F]fluoro-2-deoxy-D-glucose, we acquired time-concentration curves from three radiosensitive beta ...

Wiley-Blackwell2005