Publications related to Vegetative state

Sensory-Motor Neurostimulation to Enhance Exosuit Performance

Silvestro Micera, Andrea Crema, Stanisa Raspopovic, Giacomo Valle

Exosuits typically provide limited mechanical support and rely on a user's residual functional ability. However, people with neurological impairments often suffer from both motor and sensory deficits that limit the assistance an exosuit can provide. To ove ...

IEEE2023

Brain Fingerprinting Using Fmri Spectral Signatures On High-Resolution Cortical Graphs

Dimitri Nestor Alice Van De Ville, Maria Giulia Preti, Hamid Behjat, Stefano Moia, Carlo Ferritto

Resting-state fMRI has proven to entail subject-specific signatures that can serve as a fingerprint to identify individuals. Conventional methods are based on building a connectivity matrix based on correlation between the average time course of pairs of b ...

IEEE2023

Longitudinal evaluation of the mechanisms supporting post-stroke motor recovery using TMS-EEG coupling

Andéol Geoffroy Cadic-Melchior

Stroke is the main source of long-lasting disability, affecting dominantly motor functions. The extent and course of recovery are highly heterogeneous between patients, with a minority of patients fully recovering from their initial impairments, leaving 85 ...

EPFL2023

Cortical and subcortical changes in resting-state neuronal activity and connectivity in early symptomatic ALS and advanced frontotemporal dementia

Alessandra Griffa

The objective of this study was to examine if patterns of resting-state brain activity and functional connectivity in cortical and subcortical regions in patients with early symptomatic amyotrophic lateral sclerosis (ALS) resemble those of behavioural vari ...

ELSEVIER SCI LTD2022

The various forms of sensorimotor plasticity following limb amputation and their link with rehabilitation strategies

Estelle Emeline Raffin

Limb amputation is characterized by complex and intermingled brain reorganization processes combining sensorimotor deprivation induced by the loss of the limb per se, and compensatory behaviors, such as the over-use of the intact or remaining limb. While a ...

2021

Clustering and control for adaptation uncovers time-warped spike time patterns in cortical networks in vivo

James Bryden Isbister

How information in the nervous system is encoded by patterns of action potentials (i.e. spikes) remains an open question. Multi-neuron patterns of single spikes are a prime candidate for spike time encoding but their temporal variability requires further c ...

Nature Research2021

Structural control energy of resting-state functional brain states reveals less cost-effective brain dynamics in psychosis vulnerability

Dimitri Nestor Alice Van De Ville, Marie Schaer

How the brain's white-matter anatomy constrains brain activity is an open question that might give insights into the mechanisms that underlie mental disorders such as schizophrenia. Chromosome 22q11.2 deletion syndrome (22q11DS) is a neurodevelopmental dis ...

Wiley2021

Resting-State Brain Activity for Early Prediction Outcome in Postanoxic Patients in a Coma with Indeterminate Clinical Prognosis

Dimitri Nestor Alice Van De Ville

The authors used resting-state fMRI in a prospective study to compare whole-brain functional connectivity between patients with good and poor outcomes, implementing support vector machine learning. They automatically predicted coma outcome using resting-st ...

AMER SOC NEURORADIOLOGY2020

Automatic Pathological Speech Intelligibility Assessment Exploiting Subspace-Based Analyses

Hervé Bourlard, Ina Kodrasi, Parvaneh Janbakhshi

Competitive state-of-the-art automatic pathological speech intelligibility measures typically rely on regression training on a large number of features, require a large amount of healthy speech training data, or are applicable only to phonetically balanced ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2020

Perspectives: Hemianopia—Toward Novel Treatment Options Based on Oscillatory Activity?

Friedhelm Christoph Hummel, Estelle Emeline Raffin, Roberto Felipe Salamanca Giron

Stroke has become one of the main causes of visual impairment, with more than 15 million incidences of first-time strokes, per year, worldwide. One-third of stroke survivors exhibit visual impairment, and most of them will not fully recover. Some recovery ...

2019

The Cortical States of Wakefulness

Sylvain Crochet, James Poulet

Cortical neurons process information on a background of spontaneous, ongoing activity with distinct spatiotemporal profiles defining different cortical states. During wakefulness, cortical states alter constantly in relation to behavioral context, attentio ...

2019

Discovery and validation of temporal patterns involved in human brain ketometabolism in cerebral microdialysis fluids of traumatic brain injury patients

Sarah Catherine Sonnay, Anirikh Chakrabarti, Nicolas Christinat, Mojgan Masoodi

Background: Traumatic brain injury (TBI) is recognized as a metabolic disease, characterized by acute cerebral glucose hypo-metabolism. Adaptive metabolic responses to TBI involve the utilization of alternative energy substrates, such as ketone bodies. Cer ...

2019

Resting brain dynamics at different timescales capture distinct aspects of human behavior

Dimitri Nestor Alice Van De Ville, Raphaël Pierre Liégeois

Linking human behavior to resting-state brain function is a central question in systems neuroscience. In particular, the functional timescales at which different types of behavioral factors are encoded remain largely unexplored. The behavioral counterparts ...

Springer2019

Neuroprosthetic Technologies to Evaluate and Train Leg Motor Control in Neurologically Impaired Individuals

Camille Georgette Marie Le Goff-Mignardot

Spinal cord injury (SCI) disrupts many essential sensorimotor and autonomic functions. Consequently, individuals with SCI can face decades with permanent disabilities. Advances in clinical management have decreased morbidity, but no clinical trial has yet ...

EPFL2019

EEG paradigms as a supplemental tool to behavioral assessments of DOC

José del Rocio Millán Ruiz, Serafeim Perdikis, Andrea Serino, Jean-Paul Noel

Introduction Diagnosis and prediction of recovery in the acute phase of disorders of consciousness (DOC) are critical for subsequent medical decisions. However, reliable assessment remains elusive due to the inability of current validated clinical scales t ...

2017

Highly Dynamic Spatiotemporal Organization of Low-Frequency Activities During Behavioral States in the Mouse Cerebral Cortex

Sylvain Crochet, Pierre François Philippe Le Merre

Although low-frequency (LF < 10 Hz) activities have been considered as a hallmark of nonrapid eye movement (NREM) sleep, several studies have recently reported LF activities in the membrane potential of cortical neurons from different areas in awake mice. ...

Oxford University Press2017

Diagnostic approaches to predict persistent post-traumatic symptoms after mild traumatic brain injury - a literature review

Jean-Philippe Thiran, Alessandro Daducci

Mild traumatic brain injury (mTBI) is one of the most frequently diagnosed neurological disorders in emergency departments. Although there are established recommendations for the diagnosis and treatment in the acute stage, there is an on-going debate in wh ...

Taylor & Francis Ltd2016

Total-activation regularized deconvolution of resting-state fMRI leads to reproducible networks with spatial overlap

Dimitri Nestor Alice Van De Ville, Fikret Isik Karahanoglu

Spontaneous activations in resting-state fMRI have been shown to corroborate recurrent intrinsic functional networks. Recent studies have explored integration of brain function in terms of spatially overlapping networks. We have proposed a method to recove ...

IEEE2016

Optimizing drip irrigation for eggplant crops in semi-arid zones using evolving thresholds

Paolo Perona

Field experiments were combined with a numerical model to optimize drip irrigation management based on soil matric potential (SMP) measurements. An experimental crop of eggplant was grown in Burkina Faso from December 2014 to March 2015 and plant response ...

Elsevier2016

Prediction of long-term memory scores in MCI based on resting-state fMRI

Dimitri Nestor Alice Van De Ville, Stephan Morgenthaler, Thomas William Arthur Bolton, Maria Giulia Preti, Djalel Eddine Meskaldji

Resting-state functional MRI (rs-fMRI) opens a window on large-scale organization of brain function. However, establishing relationships between resting-state brain activity and cognitive or clinical scores is still a difficult task, in particular in terms ...

Elsevier Sci Ltd2016