Explores p53's pivotal role in cellular stability, DNA repair, and tumor suppression, emphasizing TP53 mutations and DNA double-strand break repair mechanisms.
Explores the complexity and fundamental capabilities of cancer, focusing on hallmarks like sustained proliferative signaling and evading growth suppressors.
Explores the definition, frequency, classification, and types of cancer, including carcinomas, sarcomas, hematopoietic malignancies, and neuroectodermal tumors.
Explores how inflammation promotes tumor growth and immunosuppression, focusing on the role of inflammatory cells like MDSCs and neutrophils in the tumor microenvironment.
