Publications related to Urology

System and method for a microfluidic jet generation from a compact device

The invention discloses systems and methods for generation of microfluidic jets providing a tool for very precise and localized delivery of e.g., medicaments. The proposed solution overcomes shortcomings related to miniaturization of a jet injection techno ...

2021

Residual hip dysplasia in children: osseous and cartilaginous acetabular angles to guide further treatment-a pilot study

Katarzyna Pierzchala

Purpose In case of residual hip dysplasia (RHD) in children, pelvic radiographs are sometimes insufficient to precisely evaluate the entire coverage of the femoral head, when trying to decide on the need for further reconstructive procedures. Methods This ...

2019

Development of a biologically inspired in-vitro platform for long-term assessment of commercial and innovative ureteral stents

Yves Perriard, Yoan René Cyrille Civet, Francesco Clavica

Ureteral stents are small flexible tubes which are clinically used to restore the urine drainage in presence of obstructions of the ureteral lumen such as tumours, kidney/ureteral stones. The lifetime risk of developing urinary stones is about 20% in men a ...

2019

Fiber density of collagen grafts impacts rabbit urethral regeneration

Peter Frey, Jeffrey Alan Hubbell, Hans Mattias Larsson, Elif Vardar, Kalitha Pinnagoda, Ganesh Vythilingam

There is a need for efficient and “off-the-shelf” grafts in urethral reconstructive surgery. Currently available surgical techniques require harvesting of grafts from autologous sites, with increased risk of surgical complications and added patient discomf ...

Nature Research2018

Simultaneous Recognition and Pose Estimation of Instruments in Minimally Invasive Surgery

Pascal Fua, Raphael Sznitman, Pablo Marquez Neila

Detection of surgical instruments plays a key role in ensuring patient safety in minimally invasive surgery. In this paper, we present a novel method for 2D vision-based recognition and pose estimation of surgical instruments that generalizes to different ...

2017

IGF-1-containing multi-layered collagen-fibrin hybrid scaffolds for bladder tissue engineering

Jeffrey Alan Hubbell, Peter Frey, Hans Mattias Larsson, Priscilla Suhasna Maithili Briquez, Elif Vardar, Kalitha Pinnagoda

Clinical success of bladder reconstructive procedures could be promoted by the availability of functional biomaterials. In this study, we have developed a multi-layered scaffold consisting of a bioactive fibrin layer laminated between two collagen sheets a ...

Elsevier Sci Ltd2016

New horizons for patient safety: LIGRA (LIfe Guard for Robotic surgery Assistance) An interactive platform centralizing information and control in robotic surgery Operating Rooms

Hannes Bleuler

The present paper describes LIGRA, an innovative technological solution developed in the context of the SAFROS co-funded EU project. Its general goal is to improve patient safety during minimal invasive robotic surgery. Focusing on the risks introduced in ...

Ieee2013

In-vivo performance of high-density collagen gel tubes for urethral regeneration in a rabbit model

Jeffrey Alan Hubbell, Peter Frey, Lionel Ambroise Micol

Congenital malformations or injuries of the urethra can be treated using existing autologous tissue, but these procedures are sometimes associated with severe complications. Therefore, tissue engineering may be advantageous for generating urethral grafts. ...

Elsevier2012

High-density collagen gel tubes as a matrix for primary human bladder smooth muscle cells

Jeffrey Alan Hubbell, Peter Frey, Lionel Ambroise Micol

Tissue-engineered grafts for the urinary tract are being investigated for the potential treatment of several urologic diseases. These grafts, predominantly tubular-shaped, usually require in vitro culture prior to implantation to allow cell engraftment on ...

Elsevier2011

Spinal Cord Stimulation Restores Locomotion in Animal Models of Parkinson's Disease

Miguel Nicolelis

Dopamine replacement therapy is useful for treating motor symptoms in the early phase of Parkinson's disease, but it is less effective in the long term. Electrical deep-brain stimulation is a valuable complement to pharmacological treatment but involves a ...

American Association for the Advancement of Science2009

Fluorescence cystoscopy: Perspective in clinical practice and research

Hubert van den Bergh, Georges Wagnières, Blaise Lovisa

Many studies confirm the clinical interest of photodynamic diagnostics (PDD) in non-muscle invasive bladder cancer management. PDD or fluorescence cystoscopy is not only of great value in occult urothelial cancer detection, but may have a positive impact o ...

Springer Verlag2008

Photodynamic diagnostics in the urinary tract. Consensus paper of the Working Group for Oncology of the German Society for Urology

Hubert van den Bergh

Because of the frequency of occurrence and the long protracted course, bladder carcinoma is the most expensive solid tumor in terms of costs, from diagnosis to death of the patient. The most important cost factor within the total cost is the treatment of r ...

Springer Verlag2008

Notch signaling is required for normal prostatic epithelial cell proliferation and differentiation

Freddy Radtke, Michel Aguet, Zhipeng Tang

Notch pathway is crucial for stem/progenitor cell maintenance, growth and differentiation in a variety of tissues. Using a transgenic cell ablation approach, we found in our previous study that cells expressing Notch1 are crucial for prostate early develop ...

2006