Publications related to Contrast agent

Functionalization of harmonic nanoparticles for drug release and multimodal imaging applications

Cancer is among the leading causes of death worldwide, and as knowledge of the disease continues to grow there is an increasing interest towards precision medicine: more specifically towards the theranostics field, i.e the development of targeted molecular ...

EPFL2024

Hierarchical Pricing Game for Balancing the Charging of Ride-Hailing Electric Fleets

Nikolaos Geroliminis, Nils Gustav Nilsson, Marko Maljkovic

Due to the ever-increasing popularity of ride-hailing services and the indisputable shift towards alternative fuel vehicles, the intersection of the ride-hailing market and smart electric mobility provides an opportunity to trade different services to achi ...

2023

Processing load, and not stimulus evidence, determines the duration of unconscious visual feature integration

Michael Herzog, Leila Drissi Daoudi - Kleinbauer, Lukas Vogelsang

Integration across space and time is essential for the analysis of motion, low contrast, and many more stimuli. A crucial question is what determines the duration of integration. Based on classical models of decision-making, one might expect that integrati ...

2023

Revealing the complexity of ultra-soft hydrogel re-swelling inside the brain

Stéphanie Lacour, Outman Akouissi, John Martin Kolinski, Michael Shur, Olivier Didier Christian Rizzo

The brain is an ultra-soft viscoelastic matrix. Sub-kPa hydrogels match the brain's mechanical properties but are challenging to manipulate in an implantable format. We propose a simple fabrication and processing sequence, consisting of de-hydration, patte ...

2023

Gd3+-Functionalized Lithium Niobate Nanoparticles for Dual Multiphoton and Magnetic Resonance Bioimaging

Marinella Mazzanti, Sandrine Gerber, Anne-Sophie Chauvin, Katarzyna Pierzchala, Ileana Ozana Jelescu, Jérémy Vuilleumier, Raphaël Jovita De Matos, Laura Camille Louise Nicolle, Adrian Stefan Gheata, Dario Diviani, Luigi Bonacina, Fiorella Lucarini

Harmonic nanoparticles (HNPs) have emerged as appealing exogenous probes for optical bioimaging due to their distinctive features such as long-term photostability and spectral flexibility, allowing multiphoton excitation in the classical (NIR-I) and extend ...

2022

Magnetic regulation of the luminescence of hybrid lanthanide-doped nanoparticles

Jean-Claude Bünzli

The unique optical properties of lanthanide-doped nanomaterials have made them broadly attractive to a wide range of applications in chemical, physical, and biomedical fields. As an external and real-time reg-ulation tool, the magnetic field is highly usef ...

ELSEVIER SCIENCE SA2022

Performance and reproducibility of C-13 and N-15 hyperpolarization using a cryogen-free DNP polarizer

Hikari Ananda Infinity Yoshihara, Arianna Ferrari

The setup, operational procedures and performance of a cryogen-free device for producing hyperpolarized contrast agents using dissolution dynamic nuclear polarization (dDNP) in a preclinical imaging center is described. The polarization was optimized using ...

Nature Portfolio2022

BMAT: An open-source BIDS managing and analysis tool

Meritxell Bach Cuadra, Francesco La Rosa, Maxence Charles F Wynen, Benoît Macq

Magnetic Resonance Imaging (MRI) is an established technique to study in vivo neurological disorders such as Multiple Sclerosis (MS). To avoid errors on MRI data organization and automated processing, a standard called Brain Imaging Data Structure (BIDS) h ...

ELSEVIER SCI LTD2022

Multi-antenna 3D pattern design for millimeter-wave vehicular communications

German Augusto Ramirez Arroyave

The transformation of the automotive industry towards ubiquitous connection of vehicles with all kind of external agents (V2X) motivates the use of a wide range of frequencies for several applications. Millimeter-wave (mmWave) connectivity represents a par ...

2022

Robust Phase Unwrapping via Deep Image Prior for Quantitative Phase Imaging

Michaël Unser, Matthias Lütolf, Nathalie Brandenberg, Thanh-An Michel Pham, Fangshu Yang

Quantitative phase imaging (QPI) is an emerging label-free technique that produces images containing morphological and dynamical information without contrast agents. Unfortunately, the phase is wrapped in most imaging system. Phase unwrapping is the comput ...

2021

3D reconstruction of weakly scattering objects from 2D intensity-only measurements using the Wolf transform

Demetri Psaltis, Joowon Lim, Elizabeth Elena Antoine, Ahmed Ayoub

A new approach to optical diffraction tomography (ODT) based on intensity measurements is presented. By applying the Wolf transform directly to intensity measurements, we observed unexpected behavior in the 3D reconstruction of the sample. Such a reconstru ...

2021

Validation of axial void profile measured by neutron noise techniques in CROCUS

Andreas Pautz, Vincent Pierre Lamirand, Mathieu Hursin, Oskari Ville Pakari, Pavel Frajtag

Recently a joint project has been carried out between the Paul Scherrer Institut, the Ecole Polytechnique Federale de Lausanne and swissnuclear, an industrial partner, in order to determine the axial void distribution in a channel installed in the reflecto ...

2021

Vascular-targeted micelles as a specific MRI contrast agent for molecular imaging of fibrin clots and cancer cells

Anne-Sophie Chauvin, Aurélien Thomas, Vassily Vorobiev

Molecular medical imaging is intended to increase the accuracy of diagnosis, particularly in cardiovascular and cancer-related diseases, where early detection could significantly increase the treatment success rate. In this study, we present mixed micelles ...

ELSEVIER2021

Imaging with Coherent X-rays: From the Early Synchrotron Tests to SYNAPSE

Giorgio Margaritondo

The high longitudinal and lateral coherence of synchrotron X-rays sources radically transformed radiography. Before them, the image contrast was almost only based on absorption. Coherent synchrotron sources transformed radiography into a multi-faceted tool ...

MDPI2021

Biodegradable Harmonophores for Targeted High-Resolution In Vivo Tumor Imaging

Sylvie Roke, Claire Jacqueline Léa Teulon, Ali Yasin Sonay, Shahed Behzadi, Sine Yaganoglu

Optical imaging probes have played a major role in detecting and monitoring a variety of diseases. In particular, nonlinear optical imaging probes, such as second harmonic generating (SHG) nanoprobes, hold great promise as clinical contrast agents, as they ...

2021

Ultrasound Imaging: From Physical Modeling to Deep Learning

Dimitris Perdios

Among the medical imaging modalities, ultrasound (US) imaging is one of the safest, most widespread, and least expensive method used in medical diagnosis. In the past decades, several technological advances enabled the advent of ultrafast US imaging, an ac ...

EPFL2021

Measuring compartmental T-2-orientational dependence in human brain white matter using a tiltable RF coil and diffusion-T-2 correlation MRI

Muhamed Barakovic

The anisotropy of brain white matter microstructure manifests itself in orientational-dependence of various MRI contrasts, and can result in significant quantification biases if ignored. Understanding the origins of this orientation-dependence could enhanc ...

2021

How do visual skills relate to action video game performance?

Michael Herzog, Aline Françoise Cretenoud, Oh-Hyeon Choung, Arthur Barakat

It has been claimed that video gamers possess increased perceptual and cognitive skills compared to non-video gamers. Here, we examined to which extent gaming performance in CS:GO (Counter-Strike: Global Offensive) correlates with visual performance.We tes ...

2021

Brain micro-vasculature imaging: An unsupervised deep learning algorithm for segmenting mouse brain volume probed by high-resolution phase-contrast X-ray tomography

Alessandra Patera, Anne Bonnin, Marco Stampanoni

High-throughput synchrotron-based tomographic microscopy at third generation light sources allows to probe cm-sized samples at micrometer-resolution. In this work, we present an approach to image a full mouse brain. With Indian-ink as a contrast agent, it ...

WILEY2021

Improved susceptibility-weighted imaging for high contrast and resolution thalamic nuclei mapping at 7T

Meritxell Bach Cuadra, João Pedro Forjaco Jorge, Constantin Tuleasca, José Pedro Rebelo Ferreira Marques, Frédéric Gretsch, Daniel Gallichan, Elena Najdenovska

Purpose The thalamus is an important brain structure and neurosurgical target, but its constituting nuclei are challenging to image non-invasively. Recently, susceptibility-weighted imaging (SWI) at ultra-high field has shown promising capabilities for tha ...

Wiley2020