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Association between endocrine adjuvant therapy intake timing and disease-free survival in patients with high-risk early breast cancer: results of a sub-study of the UCBG- UNIRAD trial

Background Circadian rhythms regulate cellular physiology and could in fl uence the ef fi cacy of endocrine therapy (ET) in breast cancer (BC). We prospectively tested this hypothesis within the UNIRAD adjuvant phase III trial (NCT01805271). Methods 1278 p ...

Elsevier2024

Targeting the Progesterone Receptor in Breast Cancer: Mind the Short Form!

Cathrin Brisken, Carlos Henrique Venturi Ronchi

The presurgical window of opportunity trial (WOT) MIPRA provides evidence that neoadjuvant treatment with the prog-esterone receptor (PR) antagonist mifepristone (RU486) may benefit patients with estrogen receptor-positive (ER+) breast cancer characterized ...

AMER ASSOC CANCER RESEARCH2023

Adaptive Task-Space Force Control for Humanoid-to-Human Assistance

Anastasia Bolotnikova

We envision a humanoid robot to serve as a source of additional motion-support forces in assistance for frail persons. In this context, we present a control strategy for a humanoid to adaptively regulate its assistive force contribution. First, we identify ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2021

Intent Prediction Based on Biomechanical Coordination of EMG and Vision-Filtered Gaze for End-Point Control of an Arm Prosthesis

Aude Billard, Silvestro Micera, Iason Batzianoulis, Nili Eliana Krausz

We propose a novel controller for powered prosthetic arms, where fused EMG and gaze data predict the desired end-point for a full arm prosthesis, which could drive the forward motion of individual joints. We recorded EMG, gaze, and motion-tracking during p ...

2020

Rapid Recalibration of Peri-Personal Space: Psychophysical, Electrophysiological, and Neural Network Modeling Evidence

Olaf Blanke, Bruno Herbelin, Tommaso Enrico Bertoni, Andrea Serino, Jean-Paul Noel, Elisa Pellencin

Interactions between individuals and the environment occur within the peri-personal space (PPS). The encoding of this space plastically adapts to bodily constraints and stimuli features. However, these remapping effects have not been demonstrated on an ada ...

2020

Learning Recruits Neurons Representing Previously Established Associations in the Corvid Endbrain

Galyna Pidpruzhnykova

Crows quickly learn arbitrary associations. As a neuronal correlate of this behavior, single neurons in the corvid endbrain area nidopallium caudolaterale (NCL) change their response properties during association learning. In crows performing a delayed ass ...

Mit Press2017

In a demanding task, three-handed manipulation is preferred to two-handed manipulation

Hannes Bleuler, Mohamed Bouri, Etienne Burdet, Elahe Abdi

Equipped with a third hand under their direct control, surgeons may be able to perform certain surgical interventions alone; this would reduce the need for a human assistant and related coordination difficulties. However, does human performance improve wit ...

Nature Research2016

Reliability and Adaptive Assistance in Brain-Computer Interfaces

Sareh Saeedi

Brain-computer interfaces (BCIs) aim at offering an interaction modality for people with severe motor disabilities. Despite promising advances, BCIs are still confronted with multiple challenges in determining user's intentions reliably, mainly due to high ...

EPFL2016

Front-crawl stroke descriptors variability assessment for skill characterisation

Kamiar Aminian, Farzin Dadashi, Grégoire Millet

The goal of this article is to character ise front-crawl swimming skill based on variability pattern of technique descriptors. Nine national level and nine recreational swimmers performed three 300 m trials in a 50 m outdoor pool, at 70%, 80% and 90% of th ...

Taylor & Francis2016

Discriminant Brain Connectivity Patterns of Performance Monitoring at Average and Single-Trial Levels

José del Rocio Millán Ruiz, Ricardo Andres Chavarriaga Lozano, Huaijian Zhang

Electrophysiological and neuroimaging evidence suggest the existence of common mechanisms for monitoring erroneous events, independent of the source of errors. Previous works have described modulations of theta activity in the medial frontal cortex elicite ...

Elsevier2015

Prediction of Command Delivery Time for BCI

José del Rocio Millán Ruiz, Ricardo Andres Chavarriaga Lozano, Inaki Asier Iturrate Gil, Tom Edward Carlson, Sareh Saeedi

One of the challenges in using brain computer interfaces over extended periods of time is the uncertainty in the system. This uncertainty can be due to the user's internal states, the non stationarity of the brain signals, or the variation of the class dis ...

2014

Real-time Prediction of Fast and Slow Delivery of Mental Commands in a Motor Imagery BCI: An Entropy-based Approach

José del Rocio Millán Ruiz, Michael Christoph Gastpar, Ricardo Andres Chavarriaga Lozano, Sareh Saeedi

Providing adaptive shared control for Brain- Computer Interfaces (BCIs) can result in better performance while reducing the user’s mental workload. In this respect, online estimation of accuracy and speed of command delivery are important factors. This stu ...

2012

Characterizing the EEG Correlates of Exploratory Behavior

José del Rocio Millán Ruiz, Ricardo Andres Chavarriaga Lozano, Nicolas Bourdaud

This study aims to characterize the EEG correlates of exploratory behavior. Decision making in an uncertain environment raises a conflict between two opposing needs: gathering information about the environment and exploiting this knowledge in order to opti ...

Institute of Electrical and Electronics Engineers2008