Publications related to Tremor

Context-Aware Monitoring of Hand Motor Primitives in Daily Life Activities: A Pathway to Objectively Assess Rehabilitation of Patients with Upper-Limb Neurological Impairment

The hands, our silent performers in daily life, face overwhelming challenges when neurological impairments disrupt the simple tasks that compose our daily symphony. This thesis unveils a comprehensive framework for the objective monitoring of upper-limb re ...

EPFL2024

Evaluation of antigravitational support levels provided by a passive upper-limb occupational exoskeleton in repetitive arm movements

Giulia Ramella

Upper-limb occupational exoskeletons to support the workers' upper arms are typically designed to provide antigravitational support. Although typical work activities require workers to perform static and dynamic actions, the majority of the studies in lite ...

Elsevier Sci Ltd2024

Successful MRI-Guided Focused Ultrasound Thalamotomy after Ipsilateral Gamma Knife Radiosurgery for Essential Tremor: A Case Report with Video

Constantin Tuleasca, David Paul Roger Romascano, Damien Schneider

We report the case of a 67-year-old left-handed female patient with disabling medically refractory essential tremor who underwent successful right-sided magnetic resonance-guided focused ultrasound (MRgFUS) of the ventral intermediate nucleus after ipsilat ...

Karger2023

Falls Efficacy Is Associated With Better Gait and Functional Outcomes After Rehabilitation in Older Patients

Kamiar Aminian

Objective: To examine the relationship between falls efficacy and the change in gait speed and functional status in older patients undergoing postacute rehabilitation. ...

W B SAUNDERS CO-ELSEVIER INC2021

Normalization of aberrant pretherapeutic dynamic functional connectivity of extrastriate visual system in patients who underwent thalamotomy with stereotactic radiosurgery for essential tremor: a resting-state functional MRI study

Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, Meritxell Bach Cuadra, Constantin Tuleasca, Thomas William Arthur Bolton, Elena Najdenovska

OBJECTIVE The tremor circuitry has commonly been hypothesized to be driven by one or multiple pacemakers within the cerebello-thalamo-cortical pathway, including the cerebellum, contralateral motor thalamus, and primary motor cortex. However, previous stud ...

2020

A Neural Primitive model with Sensorimotor Coordination for Dynamic Quadruped Locomotion with Malfunction Compensation

Auke Ijspeert, Azhar Aulia Saputra

In the field of quadruped locomotion, dynamic locomotion behavior, and rich integration with sensory feedback represents a significant development. In this paper, we present an efficient neural model, which includes CPG and its sensorimotor coordination, a ...

IEEE2020

ResOT: Resource-Efficient Oblique Trees for Neural Signal Classification

Mahsa Shoaran, Bingzhao Zhu

Classifiers that can be implemented on chip with minimal computational and memory resources are essential for edge computing in emerging applications such as medical and IoT devices. This paper introduces a machine learning model based on oblique decision ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2020

Consensus Paper: Experimental Neurostimulation of the Cerebellum

Traian Popa

The cerebellum is best known for its role in controlling motor behaviors. However, recent work supports the view that it also influences non-motor behaviors. The contribution of the cerebellum towards different brain functions is underscored by its involve ...

Springer2019

Detection of movement onset using EMG signals for upper-limb exoskeletons in reaching tasks

Silvestro Micera

BackgroundTo assist people with disabilities, exoskeletons must be provided with human-robot interfaces and smart algorithms capable to identify the user's movement intentions. Surface electromyographic (sEMG) signals could be suitable for this purpose, bu ...

BioMed Central2019

Pretherapeutic resting-state fMRI profiles are associated with MR signature volumes after stereotactic radiosurgical thalamotomy for essential tremor

Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, Meritxell Bach Cuadra, Thomas William Arthur Bolton, Constantin Tuleasca, Adrien Jean Régis Maurice Hilaire, Elena Najdenovska

OBJECTIVE Essential tremor (ET) is the most common movement disorder. Drug-resistant ET can benefit from standard stereotactic deep brain stimulation or radiofrequency thalamotomy or, alternatively, minimally invasive techniques, including stereotactic rad ...

AMER ASSOC NEUROLOGICAL SURGEONS2018

A Drosophila Model of Essential Tremor

Essential Tremor (ET) is one of the most common neurological diseases, with an estimated 7 million affected individuals in the US; the pathophysiology of the disorder is poorly understood. Recently, we identified a mutation (KCNS2 (Kv9.2), c.1137 T > A, p. ...

Nature Research2018

System Design and Advanced Circuit Techniques for Bi-Directional Brain-Machine Interfaces

Wen-Yang Hsu

Bi-directional brain-machine interfaces (BBMIs) that can capture electrophysiological signals and provide feedback through electrical stimulation are emerging tools with various applica-tions in fundamental neuroscience research as well as in clinical trea ...

EPFL2018

Neuroprosthetics to support impaired hand functions: A multidisciplinary approach combining brain-machine interfaces and wearable exoskeletons

Luca Randazzo

Neuroprosthetics, the discipline that aims at interfacing neural systems to artificially engineered devices, has witnessed in recent years important advancements towards the ultimate goal of augmenting and restoring human functions through technology and a ...

EPFL2018

Non-invasive Cerebellar Stimulation: a Promising Approach for Stroke Recovery?

Friedhelm Christoph Hummel, Maximilian Jonas Wessel

Non-invasive brain stimulation (NIBS) combined with behavioral training is a promising strategy to augment recovery after stroke. Current research efforts have been mainly focusing on primary motor cortex (M1) stimulation. However, the translation from pro ...

2018

Closed-Loop Functional Electrical Stimulation for Gait Training for Patients with Paraplegia

Mohamed Bouri, Solaiman Shokur

This paper presents a novel functional electrical stimulation paradigm to generate locomotion in paraplegic patients. We propose a closed-loop surface functional electrical stimulation (sFES) of 16 lower-limb muscles to produce all subphases of the gait. T ...

IEEE2018

Differential contributions of subthalamic beta rhythms and 1/f broadband activity to motor symptoms in Parkinson’s disease

José del Rocio Millán Ruiz, Stéphanie Martin, Jocelyne Bloch, Ricardo Andres Chavarriaga Lozano, Robert Leeb, Inaki Asier Iturrate Gil, Aleksander Sobolewski

Excessive beta oscillatory activity in the subthalamic nucleus (STN) is linked to Parkinson’s Disease (PD) motor symptoms. However, previous works have been inconsistent regarding the functional role of beta activity in untreated Parkinsonian states, quest ...

2018

Decoding of Self-paced Lower-Limb Movement Intention: A Case Study on the Influence Factors

José del Rocio Millán Ruiz, Ricardo Andres Chavarriaga Lozano, Dong Liu

Brain-machine interfaces (BMIs) have been applied as new rehabilitation tools for motor disabled individuals. Active involvement of cerebral activity has been shown to enhance neuroplasticity and thus to restore mobility. Various studies have focused on th ...

Frontiers Research Foundation2017

Development of Walk Assistive Orthoses for Elderly

Jeremy Olivier

The proportion of elderly people is rapidly growing and the resources to help them will soon be insufficient. An important difficulty faced by the seniors is locomotion. Among the conditions that may be responsible for gait impairment, the reduced muscular ...

EPFL2016

Multicontrast connectometry: A new tool to assess cerebellum alterations in early relapsing‐remitting multiple sclerosis

Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, David Paul Roger Romascano, Alessandro Daducci, Cristina Granziera, Djalel Eddine Meskaldji, Jonas Richiardi, Gunnar Krüger, Alexis Roche, Guillaume Bonnier, Ying-Chia Lin, Gloria Menegaz

Background: Cerebellar pathology occurs in late multiple sclerosis (MS) but little is known about cerebellar changes during early disease stages. In this study, we propose a new multicontrast “connectometry” approach to assess the structural and functional ...

Wiley-Blackwell2015

Wireless Power Transfer and Data Communication for Intracranial Neural Implants Case Study : Epilepsy Monitoring

Gürkan Yilmaz

Recording neural activities plays an important role in numerous applications ranging from brain mapping to implementation of brain-machine interfaces (BMI) to recover lost functions or to understand the mechanisms behind the neurological disorders such as ...

EPFL2014