Explores Tau pathologies in Alzheimer's and related disorders, covering hyperphosphorylation, propagation, genetic associations, and therapeutic interventions.
Explores protein aggregation in neurodegenerative diseases, emphasizing the need to rethink treatment strategies and understand the role of post-translational modifications.
Explores beta-hairpins in polyglutamine protein aggregation, focusing on Huntington's disease and the molecular mechanisms behind toxic fibril formation.
Covers Parkinson's disease, its symptoms, diagnosis challenges, and current treatment options, emphasizing the need for early biomarkers and disease-modifying therapies.
Delves into chromatin regulation's role in memory formation, genetic and epigenetic influences on learning, and the potential of HDAC inhibitors as cognitive enhancers.