Publications related to Human subject research

Seeking the new, learning from the unexpected: Computational models of surprise and novelty in the brain

Human babies have a natural desire to interact with new toys and objects, through which they learn how the world around them works, e.g., that glass shatters when dropped, but a rubber ball does not. When their predictions are proven incorrect, such as whe ...

EPFL2024

A First-in-Human Randomized Study to Assess the Safety, Tolerability, Pharmacokinetics, and Neutralization Profile of Two Investigational Long-Acting Anti-SARS-CoV-2 Monoclonal Antibodies

Didier Trono, Norman Lionel Moullan

Introduction: COVID-19 remains a significant risk for the immunocompromised given their lower responsiveness to vaccination or infection. Therefore, passive immunity through long-acting monoclonal antibodies (mAbs) offers a needed approach for pre-exposure ...

2024

Shared functional connectome fingerprints following ritualistic ayahuasca intake

Enrico Amico, Hanna Tolle, Pablo Mallaroni

The knowledge that brain functional connectomes are unique and reliable has enabled behaviourally relevant inferences at a subject level. However, whether such "fingerprints" persist under altered states of consciousness is unknown. Ayahuasca is a potent s ...

Academic Press Inc Elsevier Science2023

A review of time reversal-based methods applied to fault location in power networks

Mario Paolone, Farhad Rachidi-Haeri, Zhaoyang Wang, Reza Razzaghi

Electromagnetic time reversal (EMTR)-based methods have been applied to the problem of fault location in power networks since 2012. Over the past decade, considerable theoretical investigations have led to a continuous improvement of the EMTR method in ter ...

2023

Appropriations and Uses of Travel Time

Ludy Juliana González Villamizar

Time has always been a central factor in understanding the challenges of daily mobility. For a long time, and still today, methods of economic evaluation of transport projects have monetized time savings so that they can be included in the cost–benefit ana ...

ISTE Wiley2023

Health data privacy through homomorphic encryption and distributed ledger computing: an ethical-legal qualitative expert assessment study

Marcello Ienca

Background: Increasingly, hospitals and research institutes are developing technical solutions for sharing patient data in a privacy preserving manner. Two of these technical solutions are homomorphic encryption and distributed ledger technology. Homomorph ...

BMC2022

The role of feedback and guidance as intervention methods to foster computational thinking in educational robotics learning activities for primary school

Francesco Mondada, Jean-Philippe Pellet, Evgeniia Bonnet, Laila Abdelsalam El-Hamamsy, Christian Giang, Vaios Papaspyros, Morgane Solène Denise Chevalier, Bernard Baumberger

Computational thinking (CT) is considered an emerging competence domain linked to 21st-century competences, and educational robotics (ER) is increasingly recognised as a tool to develop CT competences. This is why researchers recommend developing intervent ...

2022

A Wearable Ultrasound Interface for Prosthetic Hand Control

Xingchen Yang

Ultrasound can non-invasively detect muscle deformations and has great potential applications in prosthetic hand control. Traditional ultrasound equipment was usually too bulky to be applied in wearable scenarios. This research presented a compact ultrasou ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2022

Design considerations for robotically assembled through-tenon timber joints

Yves Weinand, Julien Gamerro, Nicolas Henry Pierre Louis Rogeau, Pierre Latteur

This research investigates the robotic assembly of timber structures connected by wood–wood connections. As the digitization of the timber construction sector progresses, digital tools, such as industrial robotic arms and Computer Numerical Control machine ...

2022

Experimental Method to Distinguish between a Solution and a Suspension

Francesco Stellacci, Quy Ong Khac, Xufeng Xu, Ting Mao, Paulo Henrique Jacob Silva

Dispersion of objects in a fluid phase can be classified as solutions (Gibbs free energy of mixing, Delta G(mix) < 0) or suspensions (Delta G(mix) > 0) depending on their thermodynamic stability. Small objects tend to form solutions, larger ones suspension ...

WILEY2022

A data-driven perspective on the colours of metal-organic frameworks

Berend Smit, Luc Patiny, Seyedmohamad Moosavi, Kevin Maik Jablonka, Mehrdad Asgari, Christopher Patrick Ireland

Colour is at the core of chemistry and has been fascinating humans since ancient times. It is also a key descriptor of optoelectronic properties of materials and is often used to assess the success of a synthesis. However, predicting the colour of a materi ...

2021

Children, Robots, and Virtual Agents: Present and Future Challenges

Shruti Chandra, Elmira Yadollahi

Research on child-agent interaction is rapidly expanding. It is, therefore, necessary to converge our collective efforts to broaden our understanding and perspectives of how virtual agents, affect and potentially improve the well-being of children. "Childr ...

ASSOC COMPUTING MACHINERY2021

Adapting Virtual Embodiment through Reinforcement Learning

Olaf Blanke, Ronan Boulic, Bruno Herbelin, Thibault Serge Mario Porssut, Yawen Hou

In Virtual Reality, having a virtual body opens a wide range of possibilities as the participant's avatar can appear to be quite different from oneself for the sake of the targeted application (e.g. for perspective-taking). In addition, the system can part ...

2021

Material surface detection on various body parts: a preliminary study for temperature substitution for upper arm amputees

Silvestro Micera, Solaiman Shokur

Experiments have shown that healthy subjects can detect materials solely relying on the material's thermal properties at their fingertip. We are interested in developing a non-invasive temperature display for sensory substitution for patients with arm ampu ...

IEEE2021

Alpha-synuclein research: defining strategic moves in the battle against Parkinson's disease

Hilal Lashuel, Magdalena Zweckstetter

With the advent of the genetic era in Parkinson's disease (PD) research in 1997, alpha-synuclein was identified as an important player in a complex neurodegenerative disease that affects >10 million people worldwide. PD has been estimated to have an econom ...

NATURE RESEARCH2021

Transformations silencieuses : étude sur l'architecture alpine

Patrick Giromini

This thesis addresses the question of abandonment in architecture, not in its negative sense of desertion, but as a possibility offered to buildings which have lost their original purpose, which is to say those buildings from social and economic contexts w ...

EPFL2021

Learning Symmetry with Tangible Robots

Pierre Dillenbourg, Francesco Mondada, Wafa Monia Benkaouar Johal, Ayberk Özgür, Morgane Solène Denise Chevalier

Robots bring a new potential for embodied learning in classrooms. With our project, we aim to ease the task for teachers and to show the worth of tangible manipulation of robots in educational contexts. In this article, we present the design and the evalua ...

SPRINGER INTERNATIONAL PUBLISHING AG2020

Motivating Innovation: The Effect of Loss Aversion on the Willingness to Persist

Kenneth Younge

We investigate the willingness of individuals to persist at exploration in the face of failure. Prior research suggests that the organization's "tolerance for failure" may motivate greater exploration by the individual. Little is known, however, about how ...

MIT Press2020

The Indoor Chemical Human Emissions and Reactivity (ICHEAR) project: Overview of experimental methodology and preliminary results

Dusan Licina, Shen Yang

With the gradual reduction of emissions from building products, emissions from human occupants become more dominant indoors. The impact of human emissions on indoor air quality is inadequately understood. The aim of the Indoor Chemical Human Emissions and ...

WILEY2020

Stability of flexible thin-film metallization stimulation electrodes: analysis of explants after first-in-human study and improvement ofin vivoperformance

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini

Objective.Micro-fabricated neural interfaces based on polyimide (PI) are achieving increasing importance in translational research. The ability to produce well-defined micro-structures with properties that include chemical inertness, mechanical flexibility ...

2020