Publications related to Family-wise error rate

Transdiagnostic markers across the psychosis continuum: a systematic review and meta-analysis of resting state fMRI studies

Dimitri Nestor Alice Van De Ville, Farnaz Delavari

Psychotic symptoms are among the most debilitating and challenging presentations of severe psychiatric diseases, such as schizophrenia, schizoaffective, and bipolar disorder. A pathophysiological understanding of intrinsic brain activity underlying psychos ...

Frontiers Media Sa2024

Evaluating the Impact of Learner Control and Interactivity in Conversational Tutoring Systems for Persuasive Writing

Tanja Christina Käser Jacober, Thiemo Wambsganss

Conversational tutoring systems (CTSs) offer a promising avenue for individualized learning support, especially in domains like persuasive writing. Although these systems have the potential to enhance the learning process, the specific role of learner cont ...

2024

An Unbiased Method of Measuring the Ratio of Two Data Sets

Jean-Paul Richard Kneib, Huanyuan Shan

In certain cases of astronomical data analysis, the meaningful physical quantity to extract is the ratio R between two data sets. Examples include the lensing ratio, the interloper rate in spectroscopic redshift samples, and the decay rate of gravitational ...

IOP Publishing Ltd2023

Density estimation in RKHS with application to Korobov spaces in high dimensions

Fabio Nobile, Yoshihito Kazashi

A kernel method for estimating a probability density function from an independent and identically distributed sample drawn from such density is presented. Our estimator is a linear combination of kernel functions, the coefficients of which are determined b ...

2023

Social Learning with Disparate Hypotheses

Ali H. Sayed, Virginia Bordignon, Stefan Vlaski, Konstantinos Ntemos

In this paper we study the problem of social learning under multiple true hypotheses and self-interested agents. In this setup, each agent receives data that might be generated from a different hypothesis (or state) than the data other agents receive. In c ...

IEEE2022

Smart pooling: AI-powered COVID-19 informative group testing

Jorge Andres Madrid Wolff

Massive molecular testing for COVID-19 has been pointed out as fundamental to moderate the spread of the pandemic. Pooling methods can enhance testing efficiency, but they are viable only at low incidences of the disease. We propose Smart Pooling, a machin ...

Nature Portfolio2022

Evaluation and optimization of novel extraction algorithms for the automatic detection of atrial activations recorded within the pulmonary veins during atrial fibrillation

Jean-Marc Vesin, Adrian Luca, Yann Prudat, Sasan Yazdani, Etienne Pruvot

Background and objective The automated detection of atrial activations (AAs) recorded from intracardiac electrograms (IEGMs) during atrial fibrillation (AF) is challenging considering their various amplitudes, morphologies and cycle length. Activation time ...

BMC2022

Cortical and subcortical changes in resting-state neuronal activity and connectivity in early symptomatic ALS and advanced frontotemporal dementia

Alessandra Griffa

The objective of this study was to examine if patterns of resting-state brain activity and functional connectivity in cortical and subcortical regions in patients with early symptomatic amyotrophic lateral sclerosis (ALS) resemble those of behavioural vari ...

ELSEVIER SCI LTD2022

Differentiation between benign and malignant vertebral compression fractures using qualitative and quantitative analysis of a single fast spin echo T2-weighted Dixon sequence

Tom Hilbert, Sébastien Bacher

Objectives To determine and compare the qualitative and quantitative diagnostic performance of a single sagittal fast spin echo (FSE) T2-weighted Dixon sequence in differentiating benign and malignant vertebral compression fractures (VCF), using multiple r ...

SPRINGER2021

Multiple testing with test statistics following heavy-tailed distributions

Zhiwen Jiang

In multiple testing problems where the components come from a mixture model of noise and true effect, we seek to first test for the existence of the non-zero components, and then identify the true alternatives under a fixed significance level

\alpha

. Two ...

EPFL2021

FANOK: Knockoffs in Linear Time

Quentin Rebjock

We describe a series of algorithms that efficiently implement Gaussian model-X knockoffs to control the false discovery rate on large-scale feature selection problems. Identifying the knockoff distribution requires solving a large-scale semidefinite progra ...

SIAM PUBLICATIONS2021

Interpreting null models of resting-state functional MRI dynamics: not throwing the model out with the hypothesis

Dimitri Nestor Alice Van De Ville, Raphaël Pierre Liégeois

Null models are useful for assessing whether a dataset exhibits a non-trivial property of interest. These models have recently gained interest in the neuroimaging community as means to explore dynamic properties of functional Magnetic Resonance Imaging (fM ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2021

A comprehensive error rate for multiple testing

Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, Stephan Morgenthaler, Djalel Eddine Meskaldji

Over the last two decades, a large variety of type I error rates and control procedures have been proposed in the field of multiple hypotheses testing. This paper proposes a framework that includes many existing proposals by investigating procedures in whi ...

SPRINGER2020

Learning and Adaptive Data Analysis via Maximal Leakage

Michael Christoph Gastpar, Amedeo Roberto Esposito, Ibrahim Issa

There has been growing interest in studying connections between generalization error of learning algorithms and information measures. In this work, we generalize a result that employs the maximal leakage, a measure of leakage of information, and explore ho ...

IEEE2019

Advantages of fluid and white matter suppression (FLAWS) with MP2RAGE compared with double inversion recovery turbo spin echo (DIR-TSE) at 7T

Tobias Kober

Cerebrospinal fluid (CSF) and white matter (WM) signal suppression techniques allow better visualization of both WM and gray matter (GM) lesions in such disorders as multiple sclerosis and epilepsy. Recently, a technique, FLuid And White matter Suppression ...

ELSEVIER IRELAND LTD2019

Statistical Applications of Random Matrix Theory: Comparison of Two Populations

Rémy Mariétan

During the last twenty years, Random matrix theory (RMT) has produced numerous results that allow a better understanding of large random matrices. These advances have enabled interesting applications in the domain of communication. Although this theory can ...

EPFL2019

Longitudinal analysis of white matter and cortical lesions in multiple sclerosis

Meritxell Bach Cuadra, Tobias Kober, Cristina Granziera, Mario Joao Fartaria de Oliveira

Purpose: The goals of this study were to assess the performance of a novel lesion segmentation tool for longitudinal analyses, as well as to validate the generated lesion progression map between two time points using conventional and non-conventional MR se ...

2019

Statistical inference in ensemble modeling of cellular metabolism

Vassily Hatzimanikatis, Marc-Olivier Boldi, Tuure Eelis Hameri

Kinetic models of metabolism can be constructed to predict cellular regulation and devise metabolic engineering strategies, and various promising computational workflows have been developed in recent years for this. Due to the uncertainty in the kinetic pa ...

2019

The detection of two-component mixture alternatives : Theory and methods

Daria Rukina

In this thesis, we deal with one of the facets of the statistical detection problem. We study a particular type of alternative, the mixture model. We consider testing where the null hypothesis corresponds to the absence of a signal, represented by some kno ...

EPFL2018

Seasonality in cholera dynamics: A rainfall-driven model explains the wide range of patterns in endemic areas

Enrico Bertuzzo, Theo Baracchini

Seasonal patterns in cholera dynamics exhibit pronounced variability across geographical regions, showing single or multiple peaks at different times of the year. Although multiple hypotheses related to local climate variables have been proposed, an unders ...

2017