Explores DNA replication mechanisms, including speed, errors, proofreading, and semiconservative nature, emphasizing the importance of maintaining DNA fidelity through mismatch repair.
Explores single molecule sequencing strategies, including sequencing by synthesis and real-time sequencing based on zero mode waveguides, as well as DNA translocation through nanopores.
Explores DNA repair mechanisms, focusing on BER and NER, cellular responses to DNA damage, and genetic disorders impacting DNA repair and cancer susceptibility.
Explores DNA repair mechanisms, highlighting the excision repair pathway and the correction of DNA lesions induced by UV radiation and ionizing radiation.
Explores DNA repair mechanisms, including BER, MMR, NER, and repair of double-strand breaks, as well as the impact of UV-induced lesions and resistance to PARP inhibitors.
