Concept

Intracranial pressure

Related publications (29)

Large-scale in-silico analysis of CSF dynamics within the subarachnoid space of the optic nerve

BackgroundImpaired cerebrospinal fluid (CSF) dynamics is involved in the pathophysiology of neurodegenerative diseases of the central nervous system and the optic nerve (ON), including Alzheimer's and Parkinson's disease, as well as frontotemporal dementia ...

BMC2024

A Tunable Self-Offloading Module for Plantar Pressure Regulation in Diabetic Patients

Yves Perriard, Yoan René Cyrille Civet, Paolo Germano, Christian Köchli, Sofia Lydia Ntella, Kenny Jeanmonod, Bhawnath Tiwari

Plantar pressure plays a crucial role in the pathogenesis of foot ulcers among patients with diabetes and peripheral polyneuropathy. Pressure relief is a key requirement for both the prevention and treatment of plantar ulcers. Conventional medical practice ...

2024

The Cerebellum and Cognitive Function: Anatomical Evidence from a Transdiagnostic Sample

Farnaz Delavari, Charles Laidi

Multiple lines of evidence across human functional, lesion, and animal data point to a cerebellar role, in particular of crus I, crus II, and lobule VIIB, in cognitive function. However, a mapping of distinct facets of cognitive function to cerebellar stru ...

Springer2023

Preserved Corticospinal Tract Revealed by Acute Perfusion Imaging Relates to Better Outcome After Thrombectomy in Stroke

Friedhelm Christoph Hummel, Philipp Johannes Koch

BACKGROUND:The indication for mechanical thrombectomy (MT) in stroke patients with large vessel occlusion has been constantly expanded over the past years. Despite remarkable treatment effects at the group level in clinical trials, many patients remain sev ...

Lippincott Williams & Wilkins2023

Low-Intensity Electrostimulation Enhances Neuroregeneration and Improves Erectile Function in a Rat Model of Cavernous Nerve Injury

Nikolaos Stergiopoulos, Mikaël Nils Sturny, Rodrigo Araujo Fraga Da Silva

Background: Neurogenic erectile dysfunction (ED) following radical prostatectomy (RP) is a frequent complication often leading to erectile tissue remodeling and permanent ED. Low-intensity electrostimulation (LIES) has been shown to enhance peripheral nerv ...

ELSEVIER SCI LTD2022

Apparatus for treating excess intraocular fluid having an elastic membrane

Nikolaos Stergiopoulos, Constantinos Stergiopulos

Apparatus and methods are provided for treating diseases that produce elevated intraocular pressures, such as glaucoma, wherein the device includes a housing shell defining a cavity between a first end and a second end of the housing shell, and an elastic ...

2021

Development and applications of hyperpolarized 13C and 1H MR spectroscopy of cerebral metabolism at ultra-high field

Emmanuelle Ines Flatt

This thesis is composed of four studies centered on investigating cerebral metabolism using magnetic resonance spectroscopy (MRS) of hyperpolarized and non-hyperpolarized compounds at ultra-high field. In the first two chapters, we studied longitudinally t ...

EPFL2021

Neural circuits of idiopathic Normal Pressure Hydrocephalus: A perspective review of brain connectivity and symptoms meta-analysis

Dimitri Nestor Alice Van De Ville, Alessandra Griffa

Idiopathic normal pressure hydrocephalus (iNPH) is a prevalent reversible neurological disorder characterized by impaired locomotion, cognition and urinary control with ventriculomegaly. Symptoms can be relieved with cerebrospinal fluid drainage, which mak ...

PERGAMON-ELSEVIER SCIENCE LTD2020

Forecasting intracranial hypertension using multi-scale waveform metrics

Martin Jaggi, Walter Karlen

Objective: Acute intracranial hypertension is an important risk factor of secondary brain damage after traumatic brain injury. Hypertensive episodes are often diagnosed reactively, leading to late detection and lost time for intervention planning. A pro-ac ...

IOP PUBLISHING LTD2020

Origin and role of the cerebrospinal fluid bidirectional flow in the central canal

François Gallaire, Ludovic Pierre Gustave Keiser

Circulation of the cerebrospinal fluid (CSF) contributes to body axis formation and brain development. Here, we investigated the unexplained origins of the CSF flow bidirectionality in the central canal of the spinal cord of 30 hpf zebrafish embryos and it ...

2020

Transsphenoidal resection for pituitary adenoma in elderly versus younger patients: a systematic review and meta-analysis

Constantin Tuleasca

Introduction Pituitary adenomas (PA) are common intracranial tumors. In the context of the aging of the population, the question is whether postsurgical outcomes are comparable to the younger ones. The primary objective of the present study was to review p ...

2020

EyeWatch Rescue of Refractory Hypotony After Baerveldt Drainage Device Implantation: Description of a New Technique

André Mermoud, Nikolaos Stergiopoulos, Adan Villamarin, Sina Elahi

The most effective way to control glaucoma is by lowering intraocular pressure (IOP) in order to prevent the progression of the disease. Glaucoma drainage devices (GDDs) are surgical option reserved for refractory cases and have been designed to address kn ...

LIPPINCOTT WILLIAMS & WILKINS2020

Apparatus for treating excess intraocular fluid having an elastic membrane

Nikolaos Stergiopoulos, Constantinos Stergiopulos

A device (100) is provided for treating diseases that produce elevated intraocular pressures, such as glaucoma, wherein the device (100) includes a housing shell (101) defining a cavity (107) between a first end (102) and a second end (104) of the housing ...

2020

How Flow Reduction Influences the Intracranial Aneurysm Occlusion: A Prospective 4D Phase-Contrast MRI Study

Mohamed Farhat, Philippe Reymond, Pierre Bouillot

BACKGROUND AND PURPOSE: Flow-diverter stents are widely used for the treatment of wide-neck intracranial aneurysms. Various parameters may influence intracranial aneurysm thrombosis, including the flow reduction induced by flow-diverter stent implantation, ...

American Society of Neuroradiology (ASNR)2019

Longitudinal study of neonatal brain tissue volumes in preterm infants and their ability to predict neurodevelopmental outcome

Djalel Eddine Meskaldji, Laura Ioana Gui, Serafeim Loukas

Premature birth has been associated with poor neurodevelopmental outcomes. However, the relation between such outcomes and brain growth in the neonatal period has not yet been fully elucidated. This study investigates longitudinal brain development between ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2019

3D phase contrast MRI: Partial volume correction for robust blood flow quantification in small intracranial vessels

Mohamed Farhat, Pierre Bouillot

Purpose: Recent advances in 3D-PCMRI (phase contrast MRI) sequences allow for measuring the complex hemodynamics in cerebral arteries. However, the small size of these vessels vs spatial resolution can lead to non-negligible partial volume artifacts, which ...

Wiley2018

Hypertonic Lactate to Improve Cerebral Perfusion and Glucose Availability After Acute Brain Injury

Pierre Magistretti, Jocelyne Bloch

Objectives: Lactate promotes cerebral blood flow and is an efficient substrate for the brain, particularly at times of glucose shortage. Hypertonic lactate is neuroprotective after experimental brain injury; however, human data are limited. ...

LIPPINCOTT WILLIAMS & WILKINS2018

Redox dysregulation as a link between childhood trauma and psychopathological and neurocognitive profile in patients with early psychosis

Alessandra Griffa, Patric Hagmann, Kim Do

Exposure to childhood trauma (CT) increases the risk for psychosis and affects the development of brain structures, possibly through oxidative stress. As oxidative stress is also linked to psychosis, it may interact with CT, leading to a more severe clinic ...

National Academy of Sciences2018

The influence of different hydro-mechanical paths on final properties of saturated MX80 bentonite samples

Lyesse Laloui, Alessio Ferrari, Patrycja Ewelina Baryla

Compacted bentonite is considered to be used for deep geological nuclear waste disposal due to its isolation properties such as low permeability, solute retention and swelling pressure. To ensure that these properties will remain favourable throughout the ...

2018

Distribution of superparamagnetic Au/Fe nanoparticles in an isolated guinea pig brain with an intact blood brain barrier

Francesco Stellacci, Paulo Henrique Jacob Silva

Diagnosis and treatment of brain disorders, such as epilepsy, neurodegenerative diseases and tumors, would benefit from innovative approaches to deliver therapeutic or diagnostic compounds into the brain parenchyma, with either a homogeneous or a targeted ...

ROYAL SOC CHEMISTRY2018