Publications related to Wernicke's area

Driving and suppressing the human language network using large language models

Transformer models such as GPT generate human-like language and are predictive of human brain responses to language. Here, using functional-MRI-measured brain responses to 1,000 diverse sentences, we first show that a GPT-based encoding model can predict t ...

Nature Portfolio2024

Event-related causality in stereo-EEG discriminates syntactic processing of noun phrases and verb phrases

Silvestro Micera, Fiorenzo Artoni

Objective. Syntax involves complex neurobiological mechanisms, which are difficult to disentangle for multiple reasons. Using a protocol able to separate syntactic information from sound information we investigated the neural causal connections evoked by t ...

IOP Publishing Ltd2023

Combined use of intraoperative MRI and awake tailored microsurgical resection to respect functional neural networks: preliminary experience

Constantin Tuleasca

INTRODUCTION: The combined use of intraoperative MRI and awake surgery is a tailored microsurgical resection to respect functional neural networks (mainly the language and motor ones). Intraoperative MRI has been classically considered to increase the exte ...

2023

Fast-Spiking Interneurons of the Premotor Cortex Contribute to Initiation and Execution of Spontaneous Actions

Silvestro Micera, Maria Pasquini

Planning and execution of voluntary movement depend on the contribution of distinct classes of neurons in primary motor and premotor areas. However, timing and pattern of activation of GABAergic cells during specific motor behaviors remain only partly unde ...

SOC NEUROSCIENCE2023

Uncovering the neural encoding of behavior in the adult Drosophila motor system

Chin-Lin Chen

One of the most important goals in neuroscience research has always been to understand how animals control their behavior. However, the long focus on the role of brain neurons in behavioral control might be missing the full story. In fact, brain-wide fluct ...

EPFL2022

Early motor skill acquisition in healthy older adults: functional MRI and connectome correlates

Manon Chloé Durand-Ruel

decrement have been proposed, such as weakened acquisition of the motor skill. While the processes at play during the initial acquisition phase have been well-characterized in young adults, they were only scarcely investigated in older adults. The goal of ...

EPFL2022

Novel Methods for Incorporating Prior Knowledge for Automatic Speech Assessment

Subrahmanya Pavankumar Dubagunta

Speech signal conveys several kinds of information such as a message, speaker identity, emotional state of the speaker and social state of the speaker. Automatic speech assessment is a broad area that refers to using automatic methods to predict human judg ...

EPFL2021

High gamma response tracks different syntactic structures in homophonous phrases

Silvestro Micera, Fiorenzo Artoni

Syntax is a species-specific component of human language combining a finite set of words in a potentially infinite number of sentences. Since words are by definition expressed by sound, factoring out syntactic information is normally impossible. Here, we c ...

Nature Research2020

An intracerebral exploration of functional connectivity during word production

Amandine Grappe

Language is mediated by pathways connecting distant brain regions that have diverse functional roles. For word production, the network includes a ventral pathway, connecting temporal and inferior frontal regions, and a dorsal pathway, connecting parietal a ...

2019

Auditory Brainstem Implants: Recent Progress and Future Perspectives

Stéphanie Lacour, Nicolas Vachicouras

The auditory brainstem implant (ABI) was first developed nearly 40 years ago and provides auditory rehabilitation to patients who are deaf and ineligible for cochlear implant surgery due to abnormalities of the cochlea and cochlear nerve. The aims of the f ...

2019

Reactivation of Recall-Induced Neurons in the Infralimbic Cortex and the Basolateral Amygdala After Remote Fear Memory Attenuation

Johannes Gräff, Ossama Mohamed Salah El-Dien El-Sayed Ibrahim Khalaf

Whether the attenuation of traumatic memories is mediated through the suppression of the original memory trace of fear by a new memory trace of safety, or through an updating of the original fear trace towards safety has been a long-standing question at th ...

2019

Optical sensory and motor mapping of mouse dorsal cortex

Matthieu Pierre Auffret

Throughout species, including mice and humans, we all have to make decisions to fulfill our fundamentals needs: eat, drink, explore, communicate, reproduce... To make those decisions, we have to collect informations from the surrounding world and to proces ...

EPFL2018

Machine Learning in High Energy Physics Community White Paper

João Miguel das Neves Duarte, Siyuan Wang, Sofia Vallecorsa, Wenjing Wu, Igor Lakomov

Machine learning is an important applied research area in particle physics, beginning with applications to high-level physics analysis in the 1990s and 2000s, followed by an explosion of applications in particle and event identification and reconstruction ...

IOP PUBLISHING LTD2018

Understanding and Decoding Imagined Speech using Electrocorticographic Recordings in Humans

Stéphanie Martin

Certain brain disorders, resulting from brainstem infarcts, traumatic brain injury, stroke and amyotrophic lateral sclerosis, limit verbal communication despite the patient being fully aware. People that cannot communicate due to neurological disorders wou ...

EPFL2017

Evaluation of audio source separation in the context of 3D audio

Lukas Rohr

The emergence and broader availability of 3D audio systems allows for new possibilities in mixing, post-production and playback of audio content. Used in movie post-production for cinemas, as special effect by disk jockeys for example and even for live con ...

EPFL2015

MRS glucose mapping and PET joining forces: Re-evaluation of the lumped constant in the rat brain under isoflurane anaesthesia

Rolf Gruetter, João Miguel das Neves Duarte, Hongxia Lei, Malte Alf

Although numerous positron emission tomography (PET) studies with ((8) F-fluoro-deoxyglucose) FDG have reported quantitative results on cerebral glucose kinetics and consumption, there is a large variation between the absolute values found in the literatur ...

Wiley-Blackwell2014

It's All in the Eyes: Subcortical and Cortical Activation during Grotesqueness Perception in Autism

Nouchine Hadjikhani, Loyse Hippolyte, Ophélie Rogier, Britt Russo

Atypical face processing plays a key role in social interaction difficulties encountered by individuals with autism. In the current fMRI study, the Thatcher illusion was used to investigate several aspects of face processing in 20 young adults with high-fu ...

Public Library Science2013

Graph theory reveals dysconnected hubs in 22q11DS and altered nodal efficiency in patients with hallucinations

Jean-Philippe Thiran, Leila Cammoun, Marie Schaer

Schizophrenia is postulated to be the prototypical dysconnection disorder, in which hallucinations are the core symptom. Due to high heterogeneity in methodology across studies and the clinical phenotype, it remains unclear whether the structural brain dys ...

Frontiers Research Foundation2013

Detection of neuronal activity and metabolism in a model of dehydration-induced anorexia in rats at 14.1T using manganese-enhanced MRI and 1H MRS

Rolf Gruetter, Nathalie Just

In this study, hypothalamic activation was performed by dehydration-induced anorexia (DIA) and overnight food suppression (OFS) in female rats. The assessment of the hypothalamic response to these challenges by manganese-enhanced MRI showed increased neuro ...

Wiley-Blackwell2011

Semantic Trajectories : Computing and Understanding Mobility Data

Zhixian Yan

Thanks to the rapid development of mobile sensing technologies (like GPS, GSM, RFID, accelerometer, gyroscope, sound and other sensors in smartphones), the large-scale capture of evolving positioning data (called mobility data or trajectories) generated by ...

EPFL2011