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Related publications (28)

Preexisting variation in DNA damage response predicts the fate of single mycobacteria under stress

John McKinney, Neeraj Dhar, Giulia Manina, Lalit Kumar Singh

Clonal microbial populations are inherently heterogeneous, and this diversification is often considered as an adaptation strategy. In clinical infections, phenotypic diversity is found to be associated with drug tolerance, which in turn could evolve into g ...

2019

Development of an AFM-based nanomotion detection device for microbiological samples

Wojciech Chomicki

The main goals of this thesis pertain to the development of a device capable of detecting microorganism viability through monitoring the oscillations of a microscopic cantilever transducer, to improve the presently used device and to attempt to explain in ...

EPFL2019

Conjugating Biotin to Ruthenium(II) Arene Units via Phosphine Ligand Functionalization

Paul Joseph Dyson, Lucinda Kate Batchelor, Andrea Monti

Two-step functionalization of 4-diphenylphosphino benzoic acid with biotin afforded 2-(biotinyloxy)ethyl 4-(diphenylphosphanyl)benzoate (LP), that was subsequently used to synthesize the Ru(II) arene complexes [RuCl2(eta(6)-p-cymene)(LP)] (1), [Ru(C2O4)(et ...

2020

Detection of bacteria

Hubert Girault, Horst Pick, Andreas Stephan Lesch, Milica Jovic, Yingdi Zhu

A method for bacteria detection and the assessment of the antimicrobial susceptibility profile uses a bacterial viability assay based on combining a highly efficient affinity bacteria enrichment/ separation with an electrochemical redox interrogation measu ...

2019

Electrochemical Imaging of Cells and Tissues

Hubert Girault, Tzu-En Lin, Andreas Stephan Lesch

The technological and experimental progress in electrochemical imaging of biological specimens is discussed with a view on potential applications for skin cancer diagnostics, reproductive medicine and microbial testing. The electrochemical analysis of sing ...

2018

Highly Reduced Genome of the New Species Mycobacterium uberis, the Causative Agent of Nodular Thelitis and Tuberculoid Scrotitis in Livestock and a Close Relative of the Leprosy Bacilli

Stewart Cole, Andrej Benjak, Charlotte Avanzi

Nodular thelitis is a chronic enzootic infection affecting dairy cows and goats. The causative agent was recently shown to be related to the leprosy-causing bacilli Mycobacterium leprae and Mycobacterium lepromatosis. In this study, the genome of this path ...

AMER SOC MICROBIOLOGY2018

Optofluidic nanoplasmonic biosensor for label-free live cell analysis in real time

Hatice Altug, Xiaokang Li, Alexander Belushkin, Filiz Yesilköy, Maria Soler Aznar

Cell signaling activities play a critical role in physiological and disease processes. The analysis of the tumor microenvironment or the immune system activation is nowadays providing valuable insights towards disease understanding and novel therapies deve ...

2018

Nanotools and molecular techniques to rapidly identify and fight bacterial infections

Sandor Kasas, Giovanni Longo

Reducing the emergence and spread of antibiotic-resistant bacteria is one of the major healthcare issues of our century. In addition to the increased mortality, infections caused by multi-resistant bacteria drastically enhance the healthcare costs, mainly ...

Elsevier2017

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