Adrenal insufficiency

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Related publications (30)

Implication of individual differences in glucocorticoid responsiveness to stress in the development of psychopathology-like behaviour and underlying neurobiology

Sophie Elizabeth Walker

The period around puberty is a critical window in development. It is a time of neuroendocrine and neuroanatomical lability, rendering individuals highly sensitive to stress. Indeed, early adversity increases risk for psychopathology. The mechanisms via whi ...

EPFL2016

Glutamate Cysteine Ligase-Modulatory Subunit Knockout Mouse Shows Normal Insulin Sensitivity but Reduced Liver Glycogen Storage

Pierre Magistretti, Kim Do

Glutathione (GSH) deficits have been observed in several mental or degenerative illness, and so has the metabolic syndrome. The impact of a decreased glucose metabolism on the GSH system is well-known, but the effect of decreased GSH levels on the energy m ...

Frontiers Media Sa2016

Isoform switching of steroid receptor co-activator-1 attenuates glucocorticoid-induced anxiogenic amygdala CRH expression

Maladaptive glucocorticoid effects contribute to stress-related psychopathology. The glucocorticoid receptor (GR) that mediates many of these effects uses multiple signaling pathways. We have tested the hypothesis that manipulation of downstream factors (' ...

Nature Publishing Group2016

Intestinal steroidogenesis controls PPAR expression in the colon and is impaired during ulcerative colitis

Johan Auwerx

Background and aims Immune tolerance breakdown during UC involves the peroxisome proliferator-activated receptor- (PPAR), a key factor in mucosal homoeostasis and the therapeutic target of 5-aminosalycilates, which expression is impaired during UC. Here we ...

Bmj Publishing Group2015

No Scope for Social Modulation of Steroid Levels in a Year-Round Territorial Damselfish

Katarina Damjanovic

Both latitude and mating system have been proposed to shape relationships between steroid hormone levels and social behavior. Recently it has been postulated that species with long lasting non-seasonal territorial behavior have low androgen responsiveness. ...

Wiley-Blackwell2015

The effects of extrinsic stress on somatic markers and behavior are dependent on animal housing conditions

Maria del Carmen Sandi Perez, Guillaume Poirier, Michael van der Kooij, Damien Sébastien Huzard

Properties of the environment play an important role in animal wellbeing and may modulate the effects of external threats. Whereas stressors can affect emotion and impair cognition, environmental enrichment may prevent the occurrence of such negative seque ...

Pergamon-Elsevier Science Ltd2015

Vitamin E and Vitamin E Acetate Absorption from Self-assembly Systems under Pancreas Insufficiency Conditions

Martin Kussmann

We determined the bioavailability of vitamin E from self-assembly structures in patients with diagnosed chronic pancreas insufficiency. Vitamin E solubilized in dispersed inverted bicontinuous cubic phase and in micellar formulation was delivered directly ...

Swiss Chemical Soc2014

Role of the HPA axis in the long-term programming of social behaviors by peripuberty stress : behavioral, pharmacological and molecular approaches

Vandana Veenit

Stress during childhood and adolescence enhances the risk of psychopathology later in life. In fact, exposure to stress during this period is known to predispose individuals to the development of psychopathologies such as depression and anxiety disorders l ...

EPFL2013

Personality traits in rats predict vulnerability and resilience to developing stress-induced depression-like behaviors, HPA axis hyper-reactivity and brain changes in pERK1/2 activity

Maria del Carmen Sandi Perez, Maria Isabel Cordero Campana, Jorge Eduardo Castro Cifuentes, Cristina Marquez Vega, Shanaz Diessler

Emerging evidence indicates that certain behavioral traits, such as anxiety, are associated with the development of depression-like behaviors after exposure to chronic stress. However, single traits do not explain the wide variability in vulnerability to s ...

Elsevier2012

Mitochondrial Matrix Calcium Is an Activating Signal for Hormone Secretion

Kristina Schoonjans, Chikage Mataki, Andreas Wiederkehr

Mitochondrial Ca2+ signals have been proposed to accelerate oxidative metabolism and ATP production to match Ca2+-activated energy-consuming processes. Efforts to understand the signaling role of mitochondrial Ca2+ have been hampered by the inability to ma ...

Cell Press2011

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