Publications related to Physical disability

Early Neuroprotective Effects of Bovine Lactoferrin Associated with Hypothermia after Neonatal Brain Hypoxia-Ischemia in Rats

Neonatal hypoxic-ischemic (HI) encephalopathy (HIE) in term newborns is a leading cause of mortality and chronic disability. Hypothermia (HT) is the only clinically available therapeutic intervention; however, its neuroprotective effects are limited. Lacto ...

MDPI2023

Wearable Robotics for Impaired Upper-Limb Assistance and Rehabilitation: State of the Art and Future Perspectives

Silvestro Micera

Despite more than thirty-five years of research on wearable technologies to assist the upper-limb and a multitude of promising preliminary results, the goal of restoring pre-impairment quality of life of people with physical disabilities has not been fully ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2022

Gait Variability to Phenotype Common Orthopedic Gait Impairments Using Wearable Sensors

Wei Zhang, Amir Muaremi

Mobility impairments are a common symptom of age-related degenerative diseases. Gait features can discriminate those with mobility disorders from healthy individuals, yet phenotyping specific pathologies remains challenging. This study aims to identify if ...

MDPI2022

Fading of brain network fingerprint in Parkinson's disease predicts motor clinical impairment

Enrico Amico, Antonella Romano

The clinical connectome fingerprint (CCF) was recently introduced as a way to assess brain dynamics. It is an approach able to recognize individuals, based on the brain network. It showed its applicability providing network features used to predict the cog ...

Wiley2023

Real-world speed estimation using single trunk IMU: methodological challenges for impaired gait patterns

Kamiar Aminian, Anisoara Ionescu, Abolfazl Soltani

Walking speed (WS) is recognized as an important dimension of functional health and a candidate endpoint for clinical trials. To be adopted as a powerful outcome measure in clinical assessment, WS should be estimated pervasively and accurately in the real- ...

IEEE2020

Probing myelin content of the human brain with MRI: A review

Jean-Philippe Thiran, Tobias Kober, Tom Hilbert, Gian Franco Piredda

Rapid and efficient transmission of electric signals among neurons of vertebrates is ensured by myelin-insulating sheaths surrounding axons. Human cognition, sensation, and motor functions rely on the integrity of these layers, and demyelinating diseases o ...

WILEY2021

Lean synthesis and application to lower-limb exoskeletons

Tristan Hubert Vouga

Mobility impairments are the most prevalent of all disabilities, affecting the life of nearly one in 20 individuals in developed countries. In the most severe cases, they can have dramatic consequences for the social, mental and physical well-being of thos ...

EPFL2019

mano: A Wearable Hand Exoskeleton for Activities of Daily Living and Neurorehabilitation

José del Rocio Millán Ruiz, Luca Randazzo, Inaki Asier Iturrate Gil, Serafeim Perdikis

Hand sensorimotor impairments are among the most common consequences of injuries affecting the central and peripheral nervous systems, leading to a drastic reduction in the quality of life for affected individuals. Combining wearable robotic exoskeletons a ...

Ieee-Inst Electrical Electronics Engineers Inc2018

Brain-Computer Interface meets ROS: A robotic approach to mentally drive telepresence robots

Luca Tonin, Andrea Cimolato

This paper shows and evaluates a novel approach to integrate a non-invasive Brain-Computer Interface (BCI) with the Robot Operating System (ROS) to mentally drive a telepresence robot. Controlling a mobile device by using human brain signals might improve ...

IEEE COMPUTER SOC2018

Fascicular nerve stimulation and recording using a novel double-aisle regenerative electrode

Silvestro Micera

Objective. As artificial prostheses become more refined, they are most often used as a therapeutic option for hand amputation. By contrast to extra- or intraneural interfaces, regenerative nerve electrodes are designed to enable electrical interfaces with ...

Iop Publishing Ltd2017

A Novel Recessive RPGRIP1 Mutation Causing Leber Congenital Amaurosis

Background: Leber congenital amaurosis is an early-onset childhood severe retinal dystrophy, of significant genetic heterogeneity. RPGRIP1 is ubiquitously expressed, but mutations in RPGRIP1 lead to a retina-restricted phenotype, such as Leber congenital a ...

Georg Thieme Verlag Kg2016

Improving activity recognition using a wearable barometric pressure sensor in mobility-impaired stroke patients

Kamiar Aminian, Anisoara Ionescu, Arash Arami, Fabien Massé

Background Stroke survivors often suffer from mobility deficits. Current clinical evaluation methods, including questionnaires and motor function tests, cannot provide an objective measure of the patients’ mobility in daily life. Physical activity performa ...

BioMed Central2015

Unraveling dynamics of human physical activity patterns in chronic pain conditions

Kamiar Aminian, Anisoara Ionescu

Chronic pain is a complex disabling experience that negatively affects the cognitive, affective and physical functions as well as behavior. Although the interaction between chronic pain and physical functioning is a well-accepted paradigm in clinical resea ...

Nature Publishing Group2013

Lifestyle Evaluation Using Wearable Technologies: Opportunities for Stroke Patients

Kamiar Aminian, Anisoara Ionescu, Fabien Massé

Stroke is the leading cause of disabilities in the western world and may cause severe motor impairments. In the current clinical practice, progress during physical rehabilitation is assessed by a therapist for specific motor functions and through questionn ...

Springer2013

Evaluation of Proportional and Discrete Shared Control Paradigms for Low Resolution User Inputs

José del Rocio Millán Ruiz, Robert Leeb, Tom Edward Carlson, Guillaume Monnard

For people with severe physical disabilities, low resolution input devices, such as buttons, sip and puff switches and brain–computer interfaces provide an opportunity to interact with the world. However, it can be difficult to control assistive technology ...

IEEE2011

The Role of Shared-Control in BCI-based Telepresence

José del Rocio Millán Ruiz, Robert Leeb, Serafeim Perdikis, Luca Tonin, Michele Tavella

This paper discusses and evaluates the role of shared control approach in a BCI-based telepresence framework. Driving a mobile device by using human brain signals might improve the quality of life of people suffering from severely physical disabilities. By ...

Ieee Service Center, 445 Hoes Lane, Po Box 1331, Piscataway, Nj 08855-1331 Usa2010

Error-related EEG potentials in brain-computer interfaces

José del Rocio Millán Ruiz, Pierre Ferrez

People with severe motor disabilities (spinal cord injury (SCI), amyotrophic lateral sclerosis (ALS), etc.) but with intact brain functions are somehow prisoners of their own body. They need alternative ways of communication and control to interact with th ...

EPFL2007