Concept

High-content screening

Related lectures (19)

Drug Discovery: Computational Approaches

Explores the EXSCALATE4COV project, focusing on computational drug discovery for COVID-19 treatments and the collaboration between academia and industry.

Interrogating SAR in Medical Chemistry

Delves into the fundamentals of medicinal chemistry, emphasizing the interrogation of Structure-Activity Relationships (SAR) in drug design.

Interrogating SAR: Medicinal Chemistry

Covers medicinal chemistry basics, high-throughput screening, lead discovery milestones, and compound selectivity in drug optimization.

Chemical Biology: High-Throughput and High-Content Screening

Covers Chemical Biology, high-throughput screening, RNA interference, CRISPR-Cas9, and organoid differentiation for drug discovery.

Kidney-on-a-Chip Technologies

Covers the state-of-the-art kidney-on-chip technologies aiming to facilitate pharmaceutical research and eliminate animal testing.

Tissue Engineering for Cancer Research

Explores the complexity of cancer, challenges in research translation, and the applications of tissue engineering for cancer models and drug screening.

DNA-Encoded Libraries

Explores DNA-encoded libraries for drug discovery, covering synthesis techniques, pros and cons, and diverse DEL methods.

The ClpXP Proteolytic Complex: Basic Principles to Drug Discovery

Explores the ClpXP proteolytic complex, its drug targeting potential, and antimicrobial applications through compound screening.

Frontiers in Chemical Biology

Explores the druggable proteome, PROTACS strategy, ubiquitin attachment, and drug development paradigms.

Synthetic Biology: Therapeutic Advancement

Introduces synthetic biology for disease treatment, covering RNA therapeutics, drug discovery, and gene circuits.

Protein Engineering & In vitro Evolution

Explores protein engineering, screening methods, scaffold properties, computational design, and continuous evolution of biomolecules.

COVID-19 Diagnostic Tools

Explores COVID-19 diagnostic tools, SARS-CoV2 biology, and detection strategies for early and accurate diagnosis.

Electrophysiology: Ion Channels and Recordings

Explores electrophysiology principles, ion channels modulation, recording techniques, and analysis of cellular activity.

Protein Engineering & In Vitro Evolution

Explores protein engineering, computational design, and screening protein libraries to generate novel proteins with desired functions.

Fragment-Based Drug Discovery: Concepts & Technologies

Covers the concepts and technologies of fragment-based drug discovery, exploring hit identification, lead optimization, and screening methods.

Ribosome Profiling: Techniques and Applications

Explores ribosome profiling techniques, chemical applications, and translational insights in gene-specific features and behavioral responses.

Deep Generative Models in Drug Discovery

Explores the application of deep generative models in drug discovery, focusing on designing small molecules and optimizing molecular structures.

Understanding Big Data in Neuroscience

Delves into Big Data in neuroscience, analyzing large datasets and addressing challenges in data organization, standardization, integration, and visualization.

Ac-excitation of Josephson Junction currents

Explores ac-excitation of Josephson Junction currents, capacitance impact, thermal fluctuations, and SQUID operation in the voltage state.