Publications related to Lateral prefrontal cortex

Linking connectivity of deep brain stimulation of nucleus accumbens area with clinical depression improvements: a retrospective longitudinal case series

Dimitri Nestor Alice Van De Ville, Maria Giulia Preti, Thuy Anh Khoa Nguyen, Katrin Petermann, Simona Leserri

Treatment-resistant depression is a severe form of major depressive disorder and deep brain stimulation is currently an investigational treatment. The stimulation's therapeutic effect may be explained through the functional and structural connectivities be ...

Springer Heidelberg2024

Transcriptomic analysis reveals mitochondrial pathways associated with distinct adolescent behavioral phenotypes and stress response

Maria del Carmen Sandi Perez, Dogukan Hazar Ülgen, Thamyris Silva

Adolescent individuals exhibit great variability in cortical dynamics and behavioral outcomes. The developing adolescent brain is highly sensitive to social experiences and environmental insults, influencing how personality traits emerge. A distinct patter ...

2023

Ultrahigh field in vivo characterization of microstructural abnormalities in the orbitofrontal cortex and amygdala in autism

Elda Fischi Gomez, Cristina Granziera, Nouchine Hadjikhani, Guillaume Bonnier

There are currently no biomarkers for autism spectrum disorder (ASD). This neurodevelopmental condition has previously been associated with histopathological findings, including increased neuronal packing density in the amygdala, abnormal laminar cytoarchi ...

2021

TbCAPs: A toolbox for co-activation pattern analysis

Dimitri Nestor Alice Van De Ville, Thomas William Arthur Bolton, Constantin Tuleasca, Herberto Dhanis Pedro De Barros Camacho, Elenor Morgenroth, Farnaz Delavari, Eva Blondiaux, Baptiste Gauthier, Gwladys Rey, Lukasz Dawid Smigielski, Julian Gaviria

Functional magnetic resonance imaging provides rich spatio-temporal data of human brain activity during task and rest. Many recent efforts have focussed on characterising dynamics of brain activity. One notable instance is co-activation pattern (CAP) analy ...

2020

Amplified engagement of prefrontal cortex during control of voluntary action in Tourette syndrome

Sophie Jacqueline Andrée Betka

Tourette syndrome is characterized by 'unvoluntary' tics, which are compulsive, yet often temporarily suppressible. The inferior frontal gyms is implicated in motor control, including inhibition of pre-potent actions through influences on downstream subcor ...

OXFORD UNIV PRESS2020

Using connectivity-based real-time fMRI neurofeedback to modulate attentional and resting state networks in people with high trait anxiety

Elenor Morgenroth, Francesca Saviola

High levels of trait anxiety are associated with impaired attentional control, changes in brain activity during attentional control tasks and altered network resting state functional connectivity (RSFC). Specifically, dorsolateral prefrontal cortex to ante ...

2020

Lactate measurement by neurochemical profiling in the dorsolateral prefrontal cortex at 7T: accuracy, precision, and relaxation times

Pierre Magistretti, Lijing Xin, Masoumeh Dehghani Moghadam, Kim Do

Purpose This assesses the potential of measuring lactate in the human brain using three non-editing MRS methods at 7T and compares the accuracy and precision of the methods. Methods H-1 MRS data were measured in the right dorsolateral prefrontal cortex usi ...

Wiley2020

Prefrontal-Premotor Pathways and Motor Output in Well-Recovered Stroke Patients

Friedhelm Christoph Hummel

Structural brain imaging has continuously furthered our knowledge how different pathways of the human motor system contribute to residual motor output in stroke patients. Tract-related microstructure of pathways between primary and premotor areas has been ...

2019

Brain networks for engaging oneself in positive-social emotion regulation

Dimitri Nestor Alice Van De Ville, Frank Scharnowski, Yury Koush

Positive emotions facilitate cognitive performance, and their absence is associated with burdening psychiatric disorders. However, the brain networks regulating positive emotions are not well understood, especially with regard to engaging oneself in positi ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2019

Regulation of adenylyl cyclase 5 in striatal neurons confers the ability to detect coincident neuromodulatory signals

Ursula Röthlisberger, Siri Camee van Keulen, Daniele Narzi, Paolo Carloni

Author summary Adenylyl cyclases (ACs) are enzymes that can translate extracellular signals into the intracellular molecule cAMP, which is thus a 2nd messenger of extracellular events. The brain expresses nine membrane-bound AC variants, and AC5 is the dom ...

2019

Stress Impacts the Regulation Neuropeptides in the Rat Hippocampus and Prefrontal Cortex

Gregor Rainer, Laura Lozano Montes, Nan Zhao

Adverse life experience increases the lifetime risk to several stress-related psychopathologies, such as anxiety or depressive–like symptom following stress in adulthood. However, the neurochemical modulations triggered by stress have not been fully charac ...

2018

Cannabis use in early psychosis is associated with reduced glutamate levels in the prefrontal cortex

Rolf Gruetter, Lijing Xin, Kim Do

Recent studies have shown that cannabis may disrupt glutamate (Glu) signaling depressing Glu tone in frequent users. Current evidence have also consistently reported lower Glu-levels in various brain regions, particularly in the medial prefrontal cortex (m ...

Springer Verlag2018

Brain imaging of locomotion in neurological conditions

Dimitri Nestor Alice Van De Ville, Elvira Pirondini

Impaired locomotion is a frequent and major source of disability in patients with neurological conditions. Different neuroimaging methods have been used to understand the brain substrates of locomotion in various neurological diseases (mainly in Parkinson' ...

ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER2018

Alterations in brain microstructure in rats that develop abnormal aggression following peripubertal stress

Maria del Carmen Sandi Perez, Sophie Elizabeth Walker

Exposure to early adversity is implicated in the development of aggressive behaviour later in life in some but not all individuals. The reasons for the variability in response to such experiences are not clear but may relate to pre‐existing individual diff ...

2018

Whole genome grey and white matter DNA methylation profiles in dorsolateral prefrontal cortex

Johannes Gräff, Jose Vicente Sanchez Mut

The brain's neocortex is anatomically organized into grey and white matter, which are mainly composed by neuronal and glial cells, respectively. The neocortex can be further divided in different Brodmann areas according to their cytoarchitectural organizat ...

Wiley-Blackwell2017

Disentangling resting-state BOLD variability and PCC functional connectivity in 22q11.2 deletion syndrome

Dimitri Nestor Alice Van De Ville, Marie Schaer, Daniela Maria Zöller, Maria Carmela Padula

Although often ignored in fMRI studies, moment-to-moment variability of blood oxygenation level dependent (BOLD) signals reveals important information about brain function. Indeed, higher brain signal variability has been associated with better cognitive p ...

Elsevier2017

Harnessing prefrontal cognitive signals for brain-machine interfaces

José del Rocio Millán Ruiz, Ricardo Andres Chavarriaga Lozano

Brain-machine interfaces (BMIs) enable humans to interact with devices by modulating their brain signals. Despite impressive technological advancements, several obstacles remain. The most commonly used BMI control signals are derived from the brain areas i ...

Elsevier2017

Dorsal and ventral stream contributions to form-from-motion perception in a patient with form-from motion deficit: a case report

Olaf Blanke, Manuel Mercier

The main model of visual processing in primates proposes an anatomo-functional distinction between the dorsal stream, specialized in spatio-temporal information, and the ventral stream, processing essentially form information. However, these two pathways a ...

2017

Meta-analysis of real-time fMRI neurofeedback studies using individual participant data: How is brain regulation mediated?

Dimitri Nestor Alice Van De Ville, Rotem Roza Kopel, Kirsten Emmert

An increasing number of studies using real-time fMRI neurofeedback have demonstrated that successful regulation of neural activity is possible in various brain regions. Since these studies focused on the regulated region(s), little is known about the targe ...

Elsevier2016

Graph theory reveals dysconnected hubs in 22q11DS and altered nodal efficiency in patients with hallucinations

Jean-Philippe Thiran, Leila Cammoun, Marie Schaer

Schizophrenia is postulated to be the prototypical dysconnection disorder, in which hallucinations are the core symptom. Due to high heterogeneity in methodology across studies and the clinical phenotype, it remains unclear whether the structural brain dys ...

Frontiers Research Foundation2013