Publications related to Sinoatrial node

Finding information-rich electrocardiographic biomarkers to characterize atrial fibrillation

Atrial fibrillation (AF) is the most common cardiac arrhythmia; it will affect one in four adults worldwide in their lifetime. AF has serious consequences, including drastically increased risk of stroke. Catheter ablation surgery is an established treatmen ...

EPFL2023

Active force generation contributes to the complexity of spontaneous activity and to the response to stretch of murine cardiomyocyte cultures

Stéphanie Lacour

Cardiomyocyte cultures exhibit spontaneous electrical and contractile activity, as in a natural cardiac pacemaker. In such preparations, beat rate variability exhibits features similar to those of heart rate variability in vivo. Mechanical deformations and ...

WILEY2022

Correlation between conduction velocity and frequency analysis in patients with atrial fibrillation using high-density charge mapping

Jean-Marc Vesin, Lam Dang

Spectral analysis of atrial signals has been used to identify regions of interest in atrial fibrillation (AF). However, the relationship to the atrial substrate is unclear. In this study, we compare regions with dominant frequency (DF), simultaneously dete ...

SPRINGER HEIDELBERG2022

Evaluation and optimization of novel extraction algorithms for the automatic detection of atrial activations recorded within the pulmonary veins during atrial fibrillation

Jean-Marc Vesin, Adrian Luca, Yann Prudat, Sasan Yazdani, Etienne Pruvot

Background and objective The automated detection of atrial activations (AAs) recorded from intracardiac electrograms (IEGMs) during atrial fibrillation (AF) is challenging considering their various amplitudes, morphologies and cycle length. Activation time ...

BMC2022

Mathematical and numerical models for the cardiac electromechanical function

Alfio Quarteroni, Francesco Regazzoni

This paper deals with the mathematical model that describes the function of the human heart. More specifically, it addresses the equations that express the electromechanical process, that is the mechanical deformation (contraction and relaxation) of the he ...

EUROPEAN MATHEMATICAL SOC-EMS2021

Association of Heart Rate Variability With Silent Brain Infarcts in Patients With Atrial Fibrillation

Jean-Marc Vesin, Vincent Schlageter

Purpose: Silent brain infarcts (SBI) are frequently detected in patients with atrial fibrillation (AF), but it is unknown whether SBI are linked to autonomic dysfunction. We aimed to explore the association of autonomic dysfunction with SBI in AF patients. ...

FRONTIERS MEDIA SA2021

A Computational Study of the Electrophysiological Substrate in Patients Suffering From Atrial Fibrillation

Alfio Quarteroni, Andrea Manzoni

In the context of cardiac electrophysiology, we propose a novel computational approach to highlight and explain the long-debated mechanisms behind atrial fibrillation (AF) and to reliably numerically predict its induction and sustainment. A key role is pla ...

FRONTIERS MEDIA SA2021

OPF-driven Under Frequency Load Shedding in Low-Inertia Power Grids Hosting Large-scale Battery Energy Storage Systems

Mario Paolone, Asja Derviskadic, Yihui Zuo

The paper describes the formulation and application of an Optimal Power Flow (OPF)-driven Under Frequency Load Shedding (UFLS) scheme in low-inertia power grids hosting large-scale battery energy storage systems. Thanks to the accurate prediction of the sy ...

IEEE2021

Observation of a singular Weyl point surrounded by charged nodal walls in PtGa

Oleg Yazyev, Jan Hugo Dil, Quansheng Wu, Shengnan Zhang

Constrained by the Nielsen-Ninomiya no-go theorem, in all so-far experimentally determined Weyl semimetals (WSMs) the Weyl points (WPs) always appear in pairs in the momentum space with no exception. As a consequence, Fermi arcs occur on surfaces which con ...

Nature Research2021

Heart Rate Variability Triangular Index as a Predictor of Cardiovascular Mortality in Patients With Atrial Fibrillation

Jean-Marc Vesin, Vincent Schlageter

Background Impaired heart rate variability (HRV) is associated with increased mortality in sinus rhythm. However, HRV has not been systematically assessed in patients with atrial fibrillation (AF). We hypothesized that parameters of HRV may be predictive o ...

2020

Outer loop and isthmus in ventricular tachycardia circuits: Characteristics and implications

Alfio Quarteroni, Andrea Manzoni, Luca Dede', Stefano Pagani

BACKGROUND The isthmus of ventricular tachycardia (VT) circuits has been extensively characterized. Few data exist regarding the contribution of the outer loop (OL) to the VT circuit. OBJECTIVE The purpose of this study was to characterize the electrophysi ...

2020

The Cost of Scaling a Reliable Interconnection Topology

Rachid Guerraoui, Alexandre David Olivier Maurer

In distributed computing, many papers try to evaluate the message complexity of a distributed system as a function of the number of nodes n. But what about the cost of building the distributed system itself? Assuming that we want to reliably connect n node ...

2020

Mapping Biological Current Densities With Ultrafast Acoustoelectric Imaging: Application to the Beating Rat Heart

Pierre-Marc Jean Marie Dansette

Ultrafast acoustoelectric imaging (UAI) is a novel method for the mapping of biological current densities, which may improve the diagnosis and monitoring of cardiac activation diseases such as arrhythmias. This paper evaluates the feasibility of performing ...

Institute of Electrical and Electronics Engineers2019

Severe and uniform bi-atrial remodeling measured by dominant frequency analysis in persistent atrial fibrillation unresponsive to ablation

Jean-Marc Vesin, Adrian Luca, Andréa Buttu, Etienne Pruvot

Background High values of ECG and intracardiac dominant frequency (DF) are indicative of significant atrial remodeling in persistent atrial fibrillation (peAF). We hypothesized that patients with peAF unresponsive to ablation display higher ECG and intraca ...

2020

Systems and methods for rate-compatible polar codes for general channels

Seyed Hamed Hassani, Marco Mondelli

According to certain embodiments, a transmit node in a wireless communications system includes a first universal rate-compatible polar encoder and a transmitter. The first universal rate-compatible polar encoder is configured for a family of two or more ty ...

2019

Usefulness of P-Wave Duration and Morphologic Variability to Identify Patients Prone to Paroxysmal Atrial Fibrillation

Jean-Marc Vesin, Adrian Luca, Sasan Yazdani, Lukas Kappenberger

Few data are available on the assessment of P-wave beat-to-beat morphology variability and its ability to identify patients prone to paroxysmal atrial fibrillation (AF) occurrence. Aim of this study was to determine whether electrocardiographic (ECG) param ...

Excerpta Medica Inc-Elsevier Science Inc2017

A Non-linear Filter to Detect Atrial Activation from Intracardiac Electrograms

Jean-Marc Vesin, Sasan Yazdani, Andréa Buttu, Etienne Pruvot

Atrial activation (AA) detection during atrial fibrillation (AF) can be considered as a first step in estimating AF characteristics such as the AF cycle length. The detection of AA from intracardiac electrograms (EGM) remains challenging due to the constan ...

2017

Atrial fibrillation septal pacing: translation of modelling results

Adrian Luca

Aims: Atrial fibrillation (AF) septal pacing consists of rapid pacing from a ring of electrodes around the atrial septum, leading to local capture of both atria during AF. The present model-based study evaluated the impact of the number of stimulation elec ...

Oxford Univ Press2016

Nonlinear analysis of right atrial electrograms predicts termination of persistent atrial fibrillation within the left atrium by catheter ablation

Jean-Marc Vesin, Adrian Luca, Andréa Buttu, Etienne Pruvot

The termination of long-standing persistent atrial fibrillation (LS-pAF) can be achieved by stepwise catheter ablation (step-CA) within the left atrium (LA). Our study aims to applying complexity measures derived from nonlinear time series analysis in orde ...

Institute of Physics2016

How to prevent venous cannula orifice obstruction during extracorporeal circulation

Julien Favre

Venous cannula orifice obstruction is an underestimated problem during augmented cardiopulmonary bypass (CPB), which can potentially be reduced with redesigned, virtually wall-less cannula designs versus traditional percutaneous control venous cannulas. A ...

Sage Publications Ltd2015